Homo sapiens (human): 55181
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Entry
55181 CDS
T01001
Symbol
SMG8, ALKUS, C17orf71
Name
(RefSeq) SMG8 nonsense mediated mRNA decay factor
KO
K18734
protein SMG8
Organism
hsa
Homo sapiens (human)
Disease
H02535
Neurodevelopmental disorder with dysmorphic facies
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
55181 (SMG8)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA surveillance and transport factors
Surveillance factors
Other surveillance factors
55181 (SMG8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Smg8_Smg9
Motif
Other DBs
NCBI-GeneID:
55181
NCBI-ProteinID:
NP_060619
OMIM:
613175
HGNC:
25551
Ensembl:
ENSG00000167447
UniProt:
Q8ND04
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:59210035..59215230
Genome browser
AA seq
991 aa
AA seq
DB search
MAGPVSLRDLLMGASAWMGSESPGGSPTEGGGSAAGGPEPPWREDEICVVGIFGKTALRL
NSEKFSLVNTVCDRQVFPLFRHQDPGDPGPGIRTEAGAVGEAGGAEDPGAAAGGSVRGSG
AVAEGNRTEAGSQDYSLLQAYYSQESKVLYLLLTSICDNSQLLRACRALQSGEAGGGLSL
PHAEAHEFWKHQEKLQCLSLLYLFSVCHILLLVHPTCSFDITYDRVFRALDGLRQKVLPL
LKTAIKDCPVGKDWKLNCRPCPPRLLFLFQLNGALKVEPPRNQDPAHPDKPKKHSPKRRL
QHALEDQIYRIFRKSRVLTNQSINCLFTVPANQAFVYIVPGSQEEDPVGMLLDQLRSHCT
VKDPESLLVPAPLSGPRRYQVMRQHSRQQLSFHIDSSSSSSSGQLVDFTLREFLWQHVEL
VLSKKGFDDSVGRNPQPSHFELPTYQKWISAASKLYEVAIDGKEEDLGSPTGELTSKILS
SIKVLEGFLDIDTKFSENRCQKALPMAHSAYQSNLPHNYTMTVHKNQLAQALRVYSQHAR
GPAFHKYAMQLHEDCYKFWSNGHQLCEERSLTDQHCVHKFHSLPKSGEKPEADRNPPVLY
HNSRARSTGACNCGRKQAPRDDPFDIKAANYDFYQLLEEKCCGKLDHINFPVFEPSTPDP
APAKNESSPAPPDSDADKLKEKEPQTQGESTSLSLALSLGQSTDSLGTYPADPQAGGDNP
EVHGQVEVKTEKRPNFVDRQASTVEYLPGMLHSNCPKGLLPKFSSWSLVKLGPAKSYNFH
TGLDQQGFIPGTNYLMPWDIVIRTRAEDEGDLDTNSWPAPNKAIPGKRSAVVMGRGRRRD
DIARAFVGFEYEDSRGRRFMCSGPDKVMKVMGSGPKESALKALNSDMPLYILSSSQGRGL
KPHYAQLMRLFVVVPDAPLQIILMPQVQPGPPPCPVFYPEKQEITLPPDGLWVLRFPYAY
VTERGPCFPPKENVQLMSYKVLRGVLKAVTQ
NT seq
2976 nt
NT seq
+upstream
nt +downstream
nt
atggctggtcccgtgagcttgcgagaccttctaatgggagcatcagcctggatgggctct
gaaagtcccggagggtcccctactgagggcggagggagcgcggctggcggaccggagcct
ccatggcgggaggatgagatctgcgttgtgggaatcttcggcaagacggctctacgcctg
aattccgagaagttctctcttgtgaatacggtgtgcgaccgacaggtctttcctctcttt
cgccaccaagatcctggggatccaggacctggaatcagaactgaggctggcgccgtgggt
gaggccggtggagccgaggaccctggggctgcagccgggggttcagttcggggaagtgga
gctgtcgcggaaggtaaccgaactgaggcaggctcccaggactacagccttctgcaggcc
tactacagtcaggaaagcaaagttctgtatcttctcctcacctccatctgtgacaattca
cagcttctccgggcttgtcgggctcttcagagcggggaagctggaggtggactctcttta
cctcatgcagaagcacacgagttctggaagcatcaagagaagctgcagtgcctcagtctc
ctttacctattctctgtctgtcatatcttgcttctggtccatcccacttgttcctttgat
atcacttatgatcgagtattcagagccctggatgggctgagacagaaggtcctgccgctc
cttaaaacagccattaaggattgtccagttggcaaagactggaagctaaactgccgacct
tgcccacctagactccttttcctctttcaactcaatggagccctcaaggtagaacctcct
cggaaccaagacccagctcatccagacaagcccaagaaacattctcccaaaaggaggctg
cagcatgccctggaggaccagatctatagaatcttccggaagagtcgtgtcttgactaat
cagagcatcaactgcctctttactgtgcctgccaaccaagctttcgtgtacatagtaccg
ggaagccaggaggaggacccagtaggtatgttgctggaccaacttaggagtcattgtact
gtgaaggacccggaatctttgctggtgcctgcacccctttctgggcctaggcgataccag
gtgatgaggcagcacagccgacaacaactttcctttcacattgacagcagcagttccagt
tcttcaggccagctagtggatttcactcttcgggaattcctatggcagcatgtggagcta
gttctaagcaagaaaggtttcgatgacagtgtgggcaggaacccacagccttcccatttt
gaacttcctacttatcagaagtggatctcagcagcttcaaaactgtatgaggtggctatt
gatgggaaagaagaggacttggggtcacccactggagagctaacatctaagattttaagc
agtattaaagtcttggaaggatttttggatattgacacaaaattctcagaaaaccgatgc
caaaaagctttacccatggcccacagtgcctaccagtcaaatttgcctcataattacaca
atgactgtccataagaatcagcttgcccaggctcttcgagtgtacagtcaacatgctaga
ggtccagcatttcacaaatacgccatgcagttacatgaggactgctacaaattttggagc
aatggccatcagctctgtgaggagaggagtttaactgatcaacactgtgtgcacaaattt
cactcattacctaaatcaggagaaaaaccagaggctgatagaaatccgcctgtgctatat
cacaatagccgagctcgatctactggtgcttgcaactgtggaaggaaacaagcacctcga
gatgatccctttgatatcaaagcagccaattatgacttctatcagcttctggaagaaaag
tgttgtggaaaattggatcatatcaatttcccagtatttgaaccaagtactccagatcct
gctcctgctaaaaatgaatcctctcctgctcctccagattcggatgctgataaacttaaa
gaaaaagaacctcaaacccaaggagagagcacgagcctgagtttagctttgagtttgggc
caatccacagatagcttaggtacctatccagctgatccacaagcaggaggagataatcca
gaagttcatggtcaagtagaagtgaaaactgagaagaggccaaacttcgttgatcgacag
gcatccacagttgagtatctcccaggcatgctacattcaaattgccctaaaggtctccta
cccaaattctccagctggtctttggttaaactaggccctgctaagtcttataactttcat
acaggtttggaccaacagggctttattccaggaacaaattatcttatgccttgggacatt
gtcatcaggactagagctgaagatgaaggagacttagacacaaactcttggcctgctcca
aataaagctattcctggaaagagaagtgcggttgtaatgggaagaggaagacggcgagat
gacatagctcgagcttttgtgggctttgaatatgaagactctcgaggtcggagattcatg
tgctctgggcctgacaaagtaatgaaagtaatgggaagtgggccaaaggaatcagcttta
aaagccctaaatagtgacatgcccttatatattctgtcatcctctcaaggtagagggctg
aaacctcattatgctcaacttatgaggctttttgttgtggttcctgatgctcctttgcag
ataatactaatgcctcaggttcagccaggcccaccaccatgtccggtattctacccagaa
aaacaagaaatcacccttccacctgatggcctttgggttttgagatttccttatgcatat
gtgactgagagaggaccttgtttcccccctaaggaaaatgtgcagttaatgagctacaag
gtgctccgtggggttcttaaggcagtaacacaataa
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