KEGG   Homo sapiens (human): 5538
Entry
5538              CDS       T01001                                 
Symbol
PPT1, CLN1, INCL, PPT
Name
(RefSeq) palmitoyl-protein thioesterase 1
  KO
K01074  palmitoyl-protein thioesterase [EC:3.1.2.22]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00062  Fatty acid elongation
hsa01100  Metabolic pathways
hsa01212  Fatty acid metabolism
hsa04142  Lysosome
Disease
H00149  Neuronal ceroid lipofuscinosis
H02277  Santavuori-Haltia disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    5538 (PPT1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    5538 (PPT1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:hsa01004]
    5538 (PPT1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.2  Thioester hydrolases
    3.1.2.22  palmitoyl[protein] hydrolase
     5538 (PPT1)
Lipid biosynthesis proteins [BR:hsa01004]
 Fatty acid synthase
  Component type
   5538 (PPT1)
SSDB
Motif
Pfam: Palm_thioest
Other DBs
NCBI-GeneID: 5538
NCBI-ProteinID: NP_000301
OMIM: 600722
HGNC: 9325
Ensembl: ENSG00000131238
UniProt: P50897
Structure
LinkDB
Position
1:complement(40071461..40097252)
AA seq 306 aa
MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGDSCCNPLSMGAIKKMVEK
KIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQF
LRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERL
VQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVD
SEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAH
IIPFLG
NT seq 921 nt   +upstreamnt  +downstreamnt
atggcgtcgcccggctgcctgtggctcttggctgtggctctcctgccatggacctgcgct
tctcgggcgctgcagcatctggacccgccggcgccgctgccgttggtgatctggcatggg
atgggagacagctgttgcaatcccttaagcatgggtgctattaaaaaaatggtggagaag
aaaatacctggaatttacgtcttatctttagagattgggaagaccctgatggaggacgtg
gagaacagcttcttcttgaatgtcaattcccaagtaacaacagtgtgtcaggcacttgct
aaggatcctaaattgcagcaaggctacaatgctatgggattctcccagggaggccaattt
ctgagggcagtggctcagagatgcccttcacctcccatgatcaatctgatctcggttggg
ggacaacatcaaggtgtttttggactccctcgatgcccaggagagagctctcacatctgt
gacttcatccgaaaaacactgaatgctggggcgtactccaaagttgttcaggaacgcctc
gtgcaagccgaatactggcatgaccccataaaggaggatgtgtatcgcaaccacagcatc
ttcttggcagatataaatcaggagcggggtatcaatgagtcctacaagaaaaacctgatg
gccctgaagaagtttgtgatggtgaaattcctcaatgattccattgtggaccctgtagat
tcggagtggtttggattttacagaagtggccaagccaaggaaaccattcccttacaggag
acctccctgtacacacaggaccgcctggggctaaaggaaatggacaatgcaggacagcta
gtgtttctggctacagaaggggaccatcttcagttgtctgaagaatggttttatgcccac
atcataccattccttggatga

DBGET integrated database retrieval system