KEGG   Homo sapiens (human): 55737
Entry
55737             CDS       T01001                                 
Symbol
VPS35, MEM3, PARK17
Name
(RefSeq) VPS35 retromer complex component
  KO
K18468  vacuolar protein sorting-associated protein 35
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
Disease
H00057  Parkinson disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    55737 (VPS35)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    55737 (VPS35)
Membrane trafficking [BR:hsa04131]
 Endosome - Lysosome transport
  Rab GTPases and associated proteins
   Retromer subcomplex
    55737 (VPS35)
SSDB
Motif
Pfam: Vps35 FerA DUF758 Imm5 ADIP
Other DBs
NCBI-GeneID: 55737
NCBI-ProteinID: NP_060676
OMIM: 601501
HGNC: 13487
Ensembl: ENSG00000069329
Pharos: Q96QK1(Tbio)
UniProt: Q96QK1
Structure
LinkDB
Position
16:complement(46656132..46689178)
AA seq 796 aa
MPTTQQSPQDEQEKLLDEAIQAVKVQSFQMKRCLDKNKLMDALKHASNMLGELRTSMLSP
KSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQYAGNIIPRLYLLITVGVVYVK
SFPQSRKDILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDEGEPTDEETTGDISDSM
DFVLLNFAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQ
IVLTGILEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIII
ALIDRLALFAHREDGPGIPADIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMK
CYPDRVDYVDKVLETTVEIFNKLNLEHIATSSAVSKELTRLLKIPVDTYNNILTVLKLKH
FHPLFEYFDYESRKSMSCYVLSNVLDYNTEIVSQDQVDSIMNLVSTLIQDQPDQPVEDPD
PEDFADEQSLVGRFIHLLRSEDPDQQYLILNTARKHFGAGGNQRIRFTLPPLVFAAYQLA
FRYKENSKVDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHE
TVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERMKCFSEENHEPLRTQCALAASKL
LKKPDQGRAVSTCAHLFWSGRNTDKNGEELHGGKRVMECLKKALKIANQCMDPSLQVQLF
IEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRLR
RESPESEGPIYEGLIL
NT seq 2391 nt   +upstreamnt  +downstreamnt
atgcctacaacacagcagtcccctcaggatgagcaggaaaagctcttggatgaagccata
caggctgtgaaggtccagtcattccaaatgaagagatgcctggacaaaaacaagcttatg
gatgctctaaaacatgcttctaatatgcttggtgaactccggacttctatgttatcacca
aagagttactatgaactttatatggccatttctgatgaactgcactacttggaggtctac
ctgacagatgagtttgctaaaggaaggaaagtggcagatctctacgaacttgtacagtat
gctggaaacattatcccaaggctttaccttttgatcacagttggagttgtatatgtcaag
tcatttcctcagtccaggaaggatattttgaaagatttggtagaaatgtgccgtggtgtg
caacatcccttgaggggtctgtttcttcgaaattaccttcttcagtgtaccagaaatatc
ttacctgatgaaggagagccaacagatgaagaaacaactggtgacatcagtgattccatg
gattttgtactgctcaactttgcagaaatgaacaagctctgggtgcgaatgcagcatcag
ggacatagccgagatagagaaaaaagagaacgagaaagacaagaactgagaattttagtg
ggaacaaatttggtgcgcctcagtcagttggaaggtgtaaatgtggaacgttacaaacag
attgttttgactggcatattggagcaagttgtaaactgtagggatgctttggctcaagaa
tatctcatggagtgtattattcaggttttccctgatgaatttcacctccagactttgaat
ccttttcttcgggcctgtgctgagttacaccagaatgtaaatgtgaagaacataatcatt
gctttaattgatagattagctttatttgctcaccgtgaagatggacctggaatcccagcg
gatattaaactttttgatatattttcacagcaggtggctacagtgatacagtctagacaa
gacatgccttcagaggatgttgtatctttacaagtctctctgattaatcttgccatgaaa
tgttaccctgatcgtgtggactatgttgataaagttctagaaacaacagtggagatattc
aataagctcaaccttgaacatattgctaccagtagtgcagtttcaaaggaactcaccaga
cttttgaaaataccagttgacacttacaacaatattttaacagtcttgaaattaaaacat
tttcacccactctttgagtactttgactacgagtccagaaagagcatgagttgttatgtg
cttagtaatgttctggattataacacagaaattgtctctcaagaccaggtggattccata
atgaatttggtatccacgttgattcaagatcagccagatcaacctgtagaagaccctgat
ccagaagattttgctgatgagcagagccttgtgggccgcttcattcatctgctgcgctct
gaggaccctgaccagcagtacttgattttgaacacagcacgaaaacattttggagctggt
ggaaatcagcggattcgcttcacactgccacctttggtatttgcagcttaccagctggct
tttcgatataaagagaattctaaagtggatgacaaatgggaaaagaaatgccagaagatt
ttttcatttgcccaccagactatcagtgctttgatcaaagcagagctggcagaattgccc
ttaagactttttcttcaaggagcactagctgctggggaaattggttttgaaaatcatgag
acagtcgcatatgaattcatgtcccaggcattttctctgtatgaagatgaaatcagcgat
tccaaagcacagctagctgccatcaccttgatcattggcacttttgaaaggatgaagtgc
ttcagtgaagagaatcacgaacctctgaggactcagtgtgcccttgctgcatccaaactt
ctaaagaaacctgatcagggccgagctgtgagcacctgtgcacatctcttctggtctggc
agaaacacggacaaaaatggggaggagcttcacggaggcaagagggtaatggagtgccta
aaaaaagctctaaaaatagcaaatcagtgcatggacccctctctacaagtgcagcttttt
atagaaattctgaacagatatatctatttttatgaaaaggaaaatgatgcggtaacaatt
caggttttaaaccagcttatccaaaagattcgagaagacctcccgaatcttgaatccagt
gaagaaacagagcagattaacaaacattttcataacacactggagcatttgcgcttgcgg
cgggaatcaccagaatccgaggggccaatttatgaaggtctcatcctttaa

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