Homo sapiens (human): 5596
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Entry
5596 CDS
T01001
Symbol
MAPK4, ERK-4, ERK4, PRKM4, p63-MAPK, p63MAPK
Name
(RefSeq) mitogen-activated protein kinase 4
KO
K06855
mitogen-activated protein kinase 4/6 [EC:
2.7.11.24
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04657
IL-17 signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04657 IL-17 signaling pathway
5596 (MAPK4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
5596 (MAPK4)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
5596 (MAPK4)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
5596 (MAPK4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
5596
NCBI-ProteinID:
NP_002738
OMIM:
176949
HGNC:
6878
Ensembl:
ENSG00000141639
UniProt:
P31152
LinkDB
All DBs
Position
18:50559612..50731826
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AA seq
587 aa
AA seq
DB search
MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT
LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS
HKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQL
ILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDR
LTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVS
LSSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAF
EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTG
AREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLD
VFISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atggctgagaagggtgactgcatcgccagtgtctatgggtatgacctcggtgggcgcttt
gttgacttccaacccctgggcttcggtgtcaatggtttggtgctgtcggccgtggacagc
cgggcctgccggaaggtcgctgtgaagaagattgccctgagcgatgcccgcagcatgaag
cacgcgctccgagagatcaagatcattcggcgcctggaccacgacaacatcgtcaaagtg
tacgaggtgctcggtcccaagggcactgacctgcagggtgagctgttcaagttcagcgtg
gcgtacatcgtccaggagtacatggagaccgacctggcacgcctgctggagcagggcacg
ctggcagaagagcatgccaagctgttcatgtaccagctgctccgcgggctcaagtacatc
cactccgccaacgtgctgcacagggacctgaagcccgccaacatcttcatcagcacagag
gacctcgtgctcaagattggggatttcgggttggcaaggatcgttgatcagcattactcc
cacaagggttatctgtcagaagggttggtaacaaagtggtaccgttccccacgactgctc
ctttcccccaataactacaccaaagccatcgacatgtgggccgccggctgcatcctggct
gagatgcttacggggagaatgctctttgctggggcccatgagctggagcagatgcaactc
atcctggagaccatccctgtaatccgggaggaagacaaggacgagctgctcagggtgatg
ccttcctttgtcagcagcacctgggaggtgaagaggcctctgcgcaagctgctccctgaa
gtgaacagtgaagccatcgactttctggagaagatcctgacctttaaccccatggatcgc
ctaacagctgagatggggctgcaacacccctacatgagcccatactcgtgccctgaggac
gagcccacctcacaacaccccttccgcattgaggatgagatcgacgacatcgtgctgatg
gccgctaaccagagccagctgtccaactgggacacgtgcagttccaggtaccctgtgagc
ctgtcgtcggacctggagtggcggcctgaccggtgccaggacgccagcgaggtacagcgc
gacccgcgcgcgggttcggcgccactggctgaggacgtgcaggtggacccgcgcaaggac
tcgcacagcagctccgagcgcttcctagagcagtcgcactcgtccatggagcgcgccttc
gaggccgactacgggcgctcctgcgactacaaggtggggtcgccgtcctacctggacaag
ctgctgtggcgcgacaacaagccgcaccactactcggagcccaagctcatcctggacctg
tcgcactggaagcaggcggccggcgcgccccccacggccacggggctggcggacacgggg
gcgcgcgaggacgagccggccagcctcttcctggagatcgcgcagtgggtcaagagcacg
cagggcggcccagagcacgccagcccgcccgccgacgaccccgagcgccgcttgtctgcc
tcgccccccggccgcccggccccggtggacggcggcgccagcccccagttcgacctggac
gtgttcatctcccgcgccctgaagctctgcaccaagcccgaggacctgccggacaataaa
ctgggcgacctcaatggtgcgtgcatccccgagcaccctggcgacctcgtgcagaccgag
gccttctccaaagaaaggtggtga
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