Homo sapiens (human): 56339
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Entry
56339 CDS
T01001
Symbol
METTL3, IME4, M6A, MT-A70, Spo8, hMETTL3
Name
(RefSeq) methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit
KO
K05925
mRNA m6A methyltransferase catalytic subunit [EC:
2.1.1.348
]
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
56339 (METTL3)
Enzymes [BR:
hsa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.348 mRNA m6A methyltransferase
56339 (METTL3)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA processing factors
3' end processing
N6-methyltransferase complex
56339 (METTL3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MT-A70
DUF445
Motif
Other DBs
NCBI-GeneID:
56339
NCBI-ProteinID:
NP_062826
OMIM:
612472
HGNC:
17563
Ensembl:
ENSG00000165819
UniProt:
Q86U44
Structure
PDB
PDBj
LinkDB
All DBs
Position
14:complement(21498138..21511340)
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AA seq
580 aa
AA seq
DB search
MSDTWSSIQAHKKQLDSLRERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSGG
PKPSTASAVPELATDPELEKKLLHHLSDLALTLPTDAVSICLAISTPDAPATQDGVESLL
QKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRA
EQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSK
KVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFR
RIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVG
GDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIP
VLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGK
EHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNV
QPNWITLGNQLDGIHLLDPDVVARFKQRYPDGIISKPKNL
NT seq
1743 nt
NT seq
+upstream
nt +downstream
nt
atgtcggacacgtggagctctatccaggcccacaagaagcagctggactctctgcgggag
aggctgcagcggaggcggaagcaggactcggggcacttggatctacggaatccagaggca
gcattgtctccaaccttccgtagtgacagcccagtgcctactgcacccacctctggtggc
cctaagcccagcacagcttcagcagttcctgaattagctacagatcctgagttagagaag
aagttgctacaccacctctctgatctggccttaacattgcccactgatgctgtgtccatc
tgtcttgccatctccacgccagatgctcctgccactcaagatggggtagaaagcctcctg
cagaagtttgcagctcaggagttgattgaggtaaagcgaggtctcctacaagatgatgca
catcctactcttgtaacctatgctgaccattccaagctctctgccatgatgggtgctgtg
gcagaaaagaagggccctggggaggtagcagggactgtcacagggcagaagcggcgtgca
gaacaggactcgactacagtagctgcctttgccagttcgttagtctctggtctgaactct
tcagcatcggaaccagcaaaggagccagccaagaaatcaaggaaacatgctgcctcagat
gttgatctggagatagagagccttctgaaccaacagtccactaaggaacaacagagcaag
aaggtcagtcaggagatcctagagctattaaatactacaacagccaaggaacaatccatt
gttgaaaaatttcgctctcgaggtcgggcccaagtgcaagaattctgtgactatggaacc
aaggaggagtgcatgaaagccagtgatgctgatcgaccctgtcgcaagctgcacttcaga
cgaattatcaataaacacactgatgagtctttaggtgactgctctttccttaatacatgt
ttccacatggatacctgcaagtatgttcactatgaaattgatgcttgcatggattctgag
gcccctggcagcaaagaccacacgccaagccaggagcttgctcttacacagagtgtcgga
ggtgattccagtgcagaccgactcttcccacctcagtggatctgttgtgatatccgctac
ctggacgtcagtatcttgggcaagtttgcagttgtgatggctgacccaccctgggatatt
cacatggaactgccctatgggaccctgacagatgatgagatgcgcaggctcaacataccc
gtactacaggatgatggctttctcttcctctgggtcacaggcagggccatggagttgggg
agagaatgtctaaacctctgggggtatgaacgggtagatgaaattatttgggtgaagaca
aatcaactgcaacgcatcattcggacaggccgtacaggtcactggttgaaccatgggaag
gaacactgcttggttggtgtcaaaggaaatccccaaggcttcaaccagggtctggattgt
gatgtgatcgtagctgaggttcgttccaccagtcataaaccagatgaaatctatggcatg
attgaaagactatctcctggcactcgcaagattgagttatttggacgaccacacaatgtg
caacccaactggatcacccttggaaaccaactggatgggatccacctactagacccagat
gtggttgcacggttcaagcaaaggtacccagatggtatcatctctaaacctaagaattta
tag
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integrated database retrieval system
