KEGG   Homo sapiens (human): 56950
Entry
56950             CDS       T01001                                 
Symbol
SMYD2, HSKM-B, KMT3C, ZMYND14
Name
(RefSeq) SET and MYND domain containing 2
  KO
K11426  [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00310  Lysine degradation
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    56950 (SMYD2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    56950 (SMYD2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.354  [histone H3]-lysine4 N-trimethyltransferase
     56950 (SMYD2)
    2.1.1.357  [histone H3]-lysine36 N-dimethyltransferase
     56950 (SMYD2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     56950 (SMYD2)
SSDB
Motif
Pfam: zf-MYND SET MYND_ZMYND11_ZMYD8 TPR_10 TPR_12 TPR_8 TPR_NPHP3 Rgg_C Tautomerase TPR_CcmH_CycH
Other DBs
NCBI-GeneID: 56950
NCBI-ProteinID: NP_064582
OMIM: 610663
HGNC: 20982
Ensembl: ENSG00000143499
UniProt: Q9NRG4
Structure
LinkDB
Position
1:214281159..214337131
AA seq 433 aa
MRAEGLGGLERFCSPGKGRGLRALQPFQVGDLLFSCPAYAYVLTVNERGNHCEYCFTRKE
GLSKCGRCKQAFYCNVECQKEDWPMHKLECSPMVVFGENWNPSETVRLTARILAKQKIHP
ERTPSEKLLAVKEFESHLDKLDNEKKDLIQSDIAALHHFYSKHLGFPDNDSLVVLFAQVN
CNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIKPGEEVFTSY
IDLLYPTEDRNDRLRDSYFFTCECQECTTKDKDKAKVEIRKLSDPPKAEAIRDMVRYARN
VIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDWEGAL
QYGQKIIKPYSKHYPLYSLNVASMWLKLGRLYMGLEHKAAGEKALKKAIAIMEVAHGKDH
PYISEIKQEIESH
NT seq 1302 nt   +upstreamnt  +downstreamnt
atgagggccgagggcctcggcggcctggagcgcttctgcagcccgggcaaaggccggggg
ctgcgggctctgcagcccttccaggtgggggacttgctgttctcctgcccggcctatgcc
tacgtgctcacggtcaacgagcggggcaaccactgcgagtactgcttcaccaggaaagaa
ggattgtccaaatgtggaagatgcaagcaggcattttactgcaatgtggagtgtcagaaa
gaagattggcccatgcacaagctggaatgttctcccatggttgtttttggggaaaactgg
aatccctcggagactgtaagactaacagcaaggattctggccaaacagaaaatccaccca
gagagaacaccttcggaaaaattgttagctgtgaaggagtttgaatcacatctggataag
ttagacaatgagaagaaggatttgattcagagtgacatagctgctctccatcacttttac
tccaagcatctcggattccctgacaatgatagcctcgtagtactctttgcacaggttaac
tgtaatggcttcacaattgaagatgaagaactttctcatttgggatcagcgatatttcct
gatgttgcattgatgaatcatagctgttgccccaatgtcattgtgacctacaaagggacc
ctggcagaagtcagagctgtacaggaaatcaagccgggagaggaggtttttaccagctat
attgatctcctgtacccaacggaagatagaaatgaccggttaagagattcttatttcttt
acctgtgagtgccaggagtgtaccaccaaggacaaggataaggccaaggtggaaatccgg
aagctcagcgatcccccaaaggcagaagccatccgagacatggtcagatatgcacgcaac
gtcattgaagagttccggagggccaagcactataaatcccctagtgagctgctggagatc
tgcgagctcagccaggagaagatgagctctgtgtttgaggacagtaacgtgtacatgttg
cacatgatgtaccaggccatgggtgtctgcttgtacatgcaggactgggaaggagccctg
caatatggacagaaaatcattaagccctacagtaagcactatcctttgtactccctcaac
gtggcctccatgtggttgaagctagggagactctacatgggcctggaacacaaagccgca
ggggagaaagccctgaagaaggccattgcaatcatggaagtagctcacggcaaagatcat
ccatatatttctgagatcaaacaggaaattgaaagccactga

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