Homo sapiens (human): 57176
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Entry
57176 CDS
T01001
Symbol
VARS2, COXPD20, VALRS, VARS2L, VARSL
Name
(RefSeq) valyl-tRNA synthetase 2, mitochondrial
KO
K01873
valyl-tRNA synthetase [EC:
6.1.1.9
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00970
Aminoacyl-tRNA biosynthesis
Disease
H00891
Combined oxidative phosphorylation deficiency
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09122 Translation
00970 Aminoacyl-tRNA biosynthesis
57176 (VARS2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01007 Amino acid related enzymes [BR:
hsa01007
]
57176 (VARS2)
09182 Protein families: genetic information processing
03016 Transfer RNA biogenesis [BR:
hsa03016
]
57176 (VARS2)
Enzymes [BR:
hsa01000
]
6. Ligases
6.1 Forming carbon-oxygen bonds
6.1.1 Ligases forming aminoacyl-tRNA and related compounds
6.1.1.9 valine---tRNA ligase
57176 (VARS2)
Amino acid related enzymes [BR:
hsa01007
]
Aminoacyl-tRNA synthetase
Class I (U)
57176 (VARS2)
Transfer RNA biogenesis [BR:
hsa03016
]
Eukaryotic type
Aminoacyl-tRNA synthetases (AARSs)
Other AARSs
57176 (VARS2)
Prokaryotic type
57176 (VARS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
tRNA-synt_1
Anticodon_1
tRNA-synt_1g
tRNA-synt_1_2
tRNA-synt_1e
FmiP_Thoc5
tRNA-synt_1b
tRNA-synt_1f
Motif
Other DBs
NCBI-GeneID:
57176
NCBI-ProteinID:
NP_065175
OMIM:
612802
HGNC:
21642
Ensembl:
ENSG00000137411
UniProt:
Q5ST30
B4E0K6
B4DG77
LinkDB
All DBs
Position
6:30914238..30926459
Genome browser
AA seq
1063 aa
AA seq
DB search
MPHLPLASFRPPFWGLRHSRGLPRFHSVSTQSEPHGSPISRRNREAKQKRLREKQATLEA
EIAGESKSPAESIKAWRPKELVLYEIPTKPGEKKDVSGPLPPAYSPRYVEAAWYPWWVRE
GFFKPEYQARLPQATGETFSMCIPPPNVTGSLHIGHALTVAIQDALVRWHRMRGDQVLWV
PGSDHAGIATQAVVEKQLWKERGVRRHELSREAFLREVWQWKEAKGGEICEQLRALGASL
DWDRECFTMDVGSSVAVTEAFVRLYKAGLLYRNHQLVNWSCALRSAISDIEVENRPLPGH
TQLRLPGCPTPVSFGLLFSVAFPVDGEPDAEVVVGTTRPETLPGDVAVAVHPDDSRYTHL
HGRQLRHPLMGQPLPLITDYAVQPHVGTGAVKVTPAHSPADAEMGARHGLSPLNVIAEDG
TMTSLCGDWLQGLHRFVAREKIMSVLSEWGLFRGLQNHPMVLPICSRSGDVIEYLLKNQW
FVRCQEMGARAAKAVESGALELSPSFHQKNWQHWFSHIGDWCVSRQLWWGHQIPAYLVVE
DHAQGEEDCWVVGRSEAEAREVAAELTGRPGAELTLERDPDVLDTWFSSALFPFSALGWP
QETPDLARFYPLSLLETGSDLLLFWVGRMVMLGTQLTGQLPFSKVLLHPMVRDRQGRKMS
KSLGNVLDPRDIISGVEMQVLQEKLRSGNLDPAELAIVAAAQKKDFPHGIPECGTDALRF
TLCSHGVQAGDLHLSVSEVQSCRHFCNKIWNALRFILNALGEKFVPQPAEELSPSSPMDA
WILSRLALAAQECERGFLTRELSLVTHALHHFWLHNLCDVYLEAVKPVLWHSPRPLGPPQ
VLFSCADLGLRLLAPLMPFLAEELWQRLPPRPGCPPAPSISVAPYPSACSLEHWRQPELE
RRFSRVQEVVQVLRALRATYQLTKARPRVLLQSSEPGDQGLFEAFLEPLGTLGYCGAVGL
LPPGAAAPSGWAQAPLSDTAQVYMELQGLVDPQIQLPLLAARRYKLQKQLDSLTARTPSE
GEAGTQRQQKLSSLQLELSKLDKAASHLRQLMDEPPAPGSPEL
NT seq
3192 nt
NT seq
+upstream
nt +downstream
nt
atgcctcatttgcctctcgcctcttttcgaccaccattttgggggctgaggcactcacgg
ggcctccccaggtttcactccgtttctacacagtcggagccccatggatctcccatctcc
cggaggaaccgtgaagccaaacagaagcgcctgcgagagaagcaggcgactctggaggct
gagatagcaggggagagcaagtcacctgcagaatccattaaggcctggaggcctaaggag
ttagtattgtatgaaatccctacgaaacccggtgaaaagaaagatgtctctgggcccctg
cctcctgcatacagcccccgatatgttgaggctgcctggtacccgtggtgggtacgagag
ggcttcttcaaaccagaatatcaggcccggctgccccaagctacaggggagaccttttcc
atgtgtatcccacctcccaatgtcactggctccctgcacattggccacgcactcacggtg
gccatacaggatgccctcgtgcgctggcaccggatgcgtggggatcaagtgctgtgggtc
cctggttcagatcatgcaggaattgctacacaagctgtggtggagaaacaactgtggaag
gaacggggagtgaggagacatgagctgagccgggaggccttccttagggaggtgtggcag
tggaaggaggcgaaaggtggagagatctgtgagcagctgcgagctctgggtgcctccctg
gactgggatcgagagtgttttaccatggatgttggctcctcagtggctgtgactgaagct
tttgtgcggctctacaaggcggggttgctgtaccggaaccatcagcttgtcaactggtca
tgtgctttaagatcagccatctcggacattgaggtggagaaccggcccctgcctggccac
acacagcttcgactgcctggctgccccacccccgtgtcttttggcctcctattttctgtt
gccttccccgtggatggagagcctgatgcagaggttgtggtaggaaccacaaggccagag
acgctgcctggagatgtggctgtggccgttcatccagacgactcgcgatacacacatcta
cacgggcgacagcttcgtcaccccttgatggggcagcctcttcccctcatcacagactat
gctgttcagccacatgtgggcacgggggcagtgaaggtgactccagctcacagtcctgcc
gatgctgagatgggggcccgacatggcttgagccccttgaatgtcattgcggaggatggg
accatgacctccctctgcggggactggctgcagggtcttcaccggtttgtggcccgggaa
aagataatgtctgtgctgagtgaatggggcctgttccggggcctccagaaccaccccatg
gtactgcccatctgcagccgttctggggatgtgatagaatacctgctgaagaaccagtgg
tttgtccgctgccaggaaatgggggcccgagctgccaaggctgtggagtcgggggccctg
gagctcagtccctccttccaccagaagaactggcagcactggttttcccatattggggac
tggtgtgtctcccggcagctgtggtggggccatcagattccagcctacctggttgtagag
gaccatgcgcagggagaagaggactgttgggtggttgggcggtcagaggctgaggccaga
gaggtagcagcggaactgacagggaggccaggggcagagctgaccctggagagggatcct
gatgtcctagacacatggttttcttctgccctgttccccttttctgccctgggctggccc
caagagaccccagaccttgctcgtttctaccccctgtcacttttggaaacgggcagcgac
cttctgctgttctgggtgggccgcatggtcatgttggggacccagctcacagggcagctg
cccttcagcaaggtgcttcttcatcccatggttcgggacaggcagggccggaagatgagc
aagtccctggggaatgtgctggacccaagagacatcatcagtggggtggagatgcaggtg
ctgcaggaaaagctgagaagcggaaatttggaccctgcagagctggccattgtggctgca
gcacagaaaaaggactttcctcacgggatccctgagtgtgggacagatgccctgagattc
acactctgctcccatggagttcaggcgggcgacttgcacctgtcagtctctgaggtccag
agctgccgacatttctgcaacaagatctggaatgctcttcgctttatcctcaatgcttta
ggggagaaatttgtgccacagcctgctgaggagctgtctccctcctccccgatggatgcc
tggatcctgagccgccttgccctggctgcccaggagtgtgagcggggcttcctcacccga
gagctctcgctcgtcactcatgccctgcaccacttctggcttcacaacctctgtgacgtc
tacctggaggctgtgaagcccgtgctgtggcactcgccccgccccctggggccccctcag
gtcctgttctcctgcgctgacctcggcctccgcctcctggccccactgatgcccttcctg
gctgaagagctctggcagaggctgccccccaggcctggttgcccccctgcccccagcatc
tcggttgccccctaccccagcgcctgcagcttggagcactggcgccagccagagctggag
cggcgcttctcccgggtccaagaggtcgtgcaggtgctaagggctctccgagccacgtac
cagctcaccaaagcccggccccgagtgctgctgcagagctcagagcctggggaccagggc
ctcttcgaggccttcttggagcccctgggcaccctgggctactgtggggctgtgggcctg
ttacccccaggcgcagcagctccctccggctgggcccaggctccactcagtgacacggct
caagtctacatggagctgcagggcctggtggacccgcagatccagctacctctgttagcc
gcccgaaggtacaagttgcagaagcagcttgacagcctcacagccaggaccccatcagaa
ggggaggcagggactcagaggcaacaaaagctttcttccctccagctggaattgtcaaaa
ctggacaaggcagcctctcacctccggcagctgatggatgagcctccagccccagggagc
ccggagctctaa
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