Homo sapiens (human): 57449
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Entry
57449 CDS
T01001
Symbol
PLEKHG5, ARHGEF45, CMTRIC, DSMA4, GEF720, HMNR4, Syx, Tech
Name
(RefSeq) pleckstrin homology and RhoGEF domain containing G5
KO
K19464
pleckstrin homology domain-containing family G member 5
Organism
hsa
Homo sapiens (human)
Pathway
hsa05200
Pathways in cancer
Disease
H00264
Charcot-Marie-Tooth disease
H00856
Distal hereditary motor neuropathies
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
57449 (PLEKHG5)
Domain-containing proteins not elsewhere classified [BR:
hsa04990
]
Pleckstrin homology (PH) domain-containing proteins
Other PH domain-containing proteins
57449 (PLEKHG5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RhoGEF
SOS1_NGEF_PH
PH_10
PH_16
PH_5
PH_13
PH
RHG20_PH
Motif
Other DBs
NCBI-GeneID:
57449
NCBI-ProteinID:
NP_001036129
OMIM:
611101
HGNC:
29105
Ensembl:
ENSG00000171680
UniProt:
O94827
LinkDB
All DBs
Position
1:complement(6467122..6520092)
Genome browser
AA seq
1006 aa
AA seq
DB search
MHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEESSVDGKGDRKSTGLKLS
KKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDI
YLDQSNTPLSLTFEAYRFGGHYLRVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPP
ALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQEPPTPSSCSLPSGSSGSTNTGD
SWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGKLHTYSLFGLPRLPRGLRFDHDSWE
EEYDEDEDEDNACLRLEDSWRELIDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIIN
LFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTRALLQPGD
FLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDM
LAKPHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAA
VVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRMKEGKDSK
MDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVG
AYTFQASGQALCRGWVDTIYNAQNQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEE
EEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVEPGDTLSSPEFDSGPF
SSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPTSLQDFVAPGPMAELV
PRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSR
SLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSHRKRCGDL
PSGASPRVQPEPPPGVSAQHRKLTLAQLYRIRTTLLLNSTLTASEV
NT seq
3021 nt
NT seq
+upstream
nt +downstream
nt
atgcattatgatgggcatgtccgcttcgaccttcccccacaaggctctgtgctggcccgg
aacgtgtccacccggtcatgcccgccgcgcaccagccccgcagtggacttggaggaggag
gaggaggagagctctgtggatggcaaaggggaccggaagagcacaggcctgaaactctcc
aagaagaaagcaaggaggagacacacggatgacccaagcaaggaatgcttcactctgaaa
tttgacctgaatgtggacattgagacagagatcgtcccagccatgaagaagaagtcactg
ggggaggtgctgctgcctgtatttgaaaggaagggcattgcgctgggcaaagtggacatc
tacctggaccagtccaacacacccctgtccctcaccttcgaggcctacaggttcggggga
cactaccttcgtgtcaaagccccagccaagcctggagatgagggcaaggtggagcagggc
atgaaggactccaagtccctgagtttgccgattctgcggccagctgggaccgggcccccc
gccctggagcgtgtggacgcccagagccgccgggagagcctggacatcttggcccctggc
cgccgccgcaagaacatgtcggagttcctgggggaggcgagcatccccgggcaggagccc
cccacgccctccagctgctctctgcccagcggcagcagtggcagcaccaacactggcgac
agctggaagaaccgggcggccagtcgcttcagcggctttttcagctccggccccagcacc
agcgcctttggccgggaggtagacaagatggagcagctggagggcaagctgcacacctac
agcctcttcgggctgcccaggctgccccgggggctgcgcttcgaccatgactcctgggag
gaggagtacgatgaagacgaggatgaggacaatgcctgcctgaggctggaggacagctgg
cgggagctcattgatgggcatgagaagctgacccggcggcagtgccaccagcaggaggcg
gtgtgggagctgctgcacacggaggcctcctacatcaggaaactgcgggtgatcatcaac
ctgttcctgtgctgcctcctgaacctgcaagagtcagggctgctgtgtgaggtggaggcg
gagcgcctgttcagcaacatcccggagatcgcgcagctgcaccgcaggctgtgggctagc
gtgatggcgccggtgctggagaaggcgcggcgcacgcgagcgctgctacagcccggggac
ttcctcaaaggcttcaagatgttcggctcgctcttcaagccctacatccgctactgcatg
gaggaggagggctgcatggagtacatgcgcggcctgctgcgcgacaacgacctcttccgg
gcctacatcacgtgggcggagaagcacccacagtgccagaggctgaagctgagcgacatg
ctggccaaaccccaccagcggctcaccaagtacccgctgctgctcaagtcggtgctgagg
aagaccgaggagccgcgcgccaaggaggccgtcgtcgccatgatcggctccgtggagcgc
ttcatccaccacgtgaacgcgtgcatgcggcagcggcaggagcggcagcggctggcggcc
gtggtgagccgcatcgacgcctacgaggtggtggaaagcagcagcgacgaagtggacaag
ctcctgaaggaatttctgcacctggacttgacagcgcccatccctggcgcctccccggag
gagacgcggcagctgctgctggaggggagcctgaggatgaaggaggggaaggacagcaag
atggatgtgtactgcttcctcttcacggatctgctgttggtgaccaaagcagtgaagaag
gcagagaggaccagggtcatcaggccacccctgctcgtggacaagattgtgtgccgggag
ctacgggaccctgggtccttcctccttatctacctgaatgagtttcacagtgctgtaggg
gcctacacgttccaggccagtggccaggccttgtgccgtggctgggtggacaccatttac
aatgcccagaaccagctgcaacagctgcgtgcacaggagcccccaggcagtcagcagccc
ctgcagagcctggaagaggaggaggatgagcaggaggaggaagaggaggaggaggaggag
gaggaggaaggcgaggacagtggcacttcagctgccagctcccctaccatcatgcggaaa
agcagcggcagccccgactctcagcactgtgcctcagatggctccacggagaccctggcc
atggttgtggtagagcctggggacacgctgtcctcccccgagttcgacagcggtcctttc
agctcccagtctgatgagacctctctcagcaccactgcctcatctgccacgcccaccagt
gagctgctgcccctgggtccggtggacggccgctcctgctccatggactctgcctacggc
accctctccccaacctccttacaagactttgtggccccaggcccaatggcagagctagtg
cctcgggccccagagtccccacgagttccttcccctccaccctcgccccgtctccgccgc
cgcacccctgtccagctgttgagctgcccgccccacctgctcaagtctaagtccgaggcc
agcctcctccagctgctggcaggggctggcacccatgggacaccctctgcccccagccgc
agcctgtcagagctctgcctggctgttccagccccaggtattaggactcagggctcccct
caggaagctgggcccagctgggattgccgaggggcccctagccctggcagcggtcctggg
ctagtcggctgcctggccggggaacctgcaggctcccacaggaagaggtgtggagacctg
ccctcgggggcctctcccagggtccagcctgagcccccaccaggggtctctgcccagcac
aggaagctgaccctggcccagctctaccgaatcaggaccaccctgctgcttaactccacg
ctcactgcctcggaggtctga
DBGET
integrated database retrieval system
