Homo sapiens (human): 57505
Help
Entry
57505 CDS
T01001
Symbol
AARS2, AARSL, COXPD8, LKENP, MT-ALARS, MTALARS
Name
(RefSeq) alanyl-tRNA synthetase 2, mitochondrial
KO
K01872
alanyl-tRNA synthetase [EC:
6.1.1.7
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00970
Aminoacyl-tRNA biosynthesis
Disease
H00891
Combined oxidative phosphorylation deficiency
H02200
Leukoencephalopathy, progressive, with ovarian failure
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09122 Translation
00970 Aminoacyl-tRNA biosynthesis
57505 (AARS2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01007 Amino acid related enzymes [BR:
hsa01007
]
57505 (AARS2)
09182 Protein families: genetic information processing
03016 Transfer RNA biogenesis [BR:
hsa03016
]
57505 (AARS2)
Enzymes [BR:
hsa01000
]
6. Ligases
6.1 Forming carbon-oxygen bonds
6.1.1 Ligases forming aminoacyl-tRNA and related compounds
6.1.1.7 alanine---tRNA ligase
57505 (AARS2)
Amino acid related enzymes [BR:
hsa01007
]
Aminoacyl-tRNA synthetase
Class II (C/G)
57505 (AARS2)
Transfer RNA biogenesis [BR:
hsa03016
]
Eukaryotic type
Aminoacyl-tRNA synthetases (AARSs)
Other AARSs
57505 (AARS2)
Prokaryotic type
57505 (AARS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
tRNA-synt_2c
tRNA_SAD
Motif
Other DBs
NCBI-GeneID:
57505
NCBI-ProteinID:
NP_065796
OMIM:
612035
HGNC:
21022
Ensembl:
ENSG00000124608
UniProt:
Q5JTZ9
Structure
PDB
PDBj
LinkDB
All DBs
Position
6:complement(44298731..44313347)
Genome browser
AA seq
985 aa
AA seq
DB search
MAASVAAAARRLRRAIRRSPAWRGLSHRPLSSEPPAAKASAVRAAFLNFFRDRHGHRLVP
SASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSEMAGFRRVANSQKCVRAGGHHNDLED
VGRDLSHHTFFEMLGNWAFGGEYFKEEACNMAWELLTQVYGIPEERLWISYFDGDPKAGL
DPDLETRDIWLSLGVPASRVLSFGPQENFWEMGDTGPCGPCTEIHYDLAGGVGAPQLVEL
WNLVFMQHNREADGSLQPLPQRHVDTGMGLERLVAVLQGKHSTYDTDLFSPLLNAIQQGC
RAPPYLGRVGVADEGRTDTAYRVVADHIRTLSVCISDGIFPGMSGPPLVLRRILRRAVRF
SMEILKAPPGFLGSLVPVVVETLGDAYPELQRNSAQIANLVSEDEAAFLASLERGRRIID
RTLRTLGPSDMFPAEVAWSLSLCGDLGLPLDMVELMLEEKGVQLDSAGLERLAQEEAQHR
ARQAEPVQKQGLWLDVHALGELQRQGVPPTDDSPKYNYSLRPSGSYEFGTCEAQVLQLYT
EDGTAVASVGKGQRCGLLLDRTNFYAEQGGQASDRGYLVRAGQEDVLFPVARAQVCGGFI
LHEAVAPECLRLGDQVQLHVDEAWRLGCMAKHTATHLLNWALRQTLGPGTEQQGSHLNPE
QLRLDVTTQTPLTPEQLRAVENTVQEAVGQDEAVYMEEVPLALTAQVPGLRSLDEVYPDP
VRVVSVGVPVAHALDPASQAALQTSVELCCGTHLLRTGAVGDLVIIGDRQLSKGTTRLLA
VTGEQAQQARELGQSLAQEVKAATERLSLGSRDVAEALRLSKDIGRLIEAVETAVMPQWQ
RRELLATVKMLQRRANTAIRKLQMGQAAKKTQELLERHSKGPLIVDTVSAESLSVLVKVV
RQLCEQAPSTSVLLLSPQPMGKVLCACQVAQGAMPTFTAEAWALAVCSHMGGKAWGSRVV
AQGTGSTTDLEAALSIAQTYALSQL
NT seq
2958 nt
NT seq
+upstream
nt +downstream
nt
atggcagcgtcagtggcagctgcagcccggaggctgcggcgggccattcgaaggtcgccc
gcatggcggggcctcagccatcggccgctctcatcggagccccctgcagccaaggcctcg
gccgtgagggccgcctttctgaacttctttcgggaccgccatggccaccggctggtgccc
tccgcttccgtgcggccccgcggcgaccccagtttgctttttgtcaatgcgggcatgaac
cagttcaagccaatctttctgggcaccgtggatccacgaagcgagatggcaggcttccga
cgtgtggccaacagccagaaatgtgtgagagctggaggacaccataacgacctggaagat
gtgggtcgagacctttcccatcataccttctttgaaatgcttggcaattgggcctttggg
ggtgaatattttaaggaggaggcttgtaacatggcctgggaactgctgactcaggtctat
gggatccctgaggaaaggctctggatctcctactttgatggtgaccccaaggcagggctg
gacccagacctggagaccagggacatctggctgagcttaggggtgcctgctagccgtgtg
ctttcctttggaccacaagagaacttctgggagatgggggatactggcccttgtgggccc
tgtactgagatccactacgaccttgctggtggggtgggagccccccagctggtagagctt
tggaacctggtcttcatgcaacacaacagagaggcagatggaagcctgcagcccctgccc
cagcggcatgtggacacaggaatgggcctggaaaggctggtggctgtgctgcaaggcaaa
cactccacctatgacactgacctcttttccccgctgctcaacgccatacagcagggctgc
agggcacccccttacttgggccgagtaggggtggcagacgaggggcgcacagacacagcg
taccgcgtggtggctgaccacatccgcacactcagtgtctgcatctctgatggcatcttc
cctgggatgtcaggtcccccgctggttcttcgtcggatcctgcgtcgagctgtgcgtttc
tccatggagatcttaaaggcaccacctggcttcctaggcagcctggtacctgtagtggtg
gagacactgggagatgcttatccagaactgcaaaggaactcagcccagatcgccaacctg
gtgtcagaggacgaggcagccttcctggcctccctggagcggggtaggcggatcattgat
cggactctgaggaccctggggccttcagatatgttccctgctgaagtggcctggtccttg
tcactgtgtggagacctgggactccccttggacatggtagagctgatgctggaggagaaa
ggggtccagctagactccgctggactggagcggttggcccaagaggaggcccagcaccgg
gcacggcaggctgagccagttcagaagcagggattgtggcttgatgtccatgcgcttggg
gagctgcagcgccaaggagtgcccccaactgacgacagccccaagtacaactactccctg
cgacccagcggaagttatgagttcggcacctgtgaggcccaggtgttgcaactgtataca
gaggacgggacagcagtggcctccgtggggaaaggccagcgctgtggcctcctcttggac
aggaccaacttctacgcagaacaggggggccaggcttcagaccgtggctacctggtgcgg
gcagggcaagaggacgtgctgttcccagtagcccgggcccaggtctgtggaggtttcatc
ctgcatgaggcagtagcccctgagtgcctgcggttaggggaccaggtgcagctgcatgtg
gatgaggcctggcgtctaggctgcatggcgaagcatacggccacccacctgctgaactgg
gcactgaggcagaccctgggccctggcacagagcagcagggctcccatctcaatcctgag
cagctgcgcttggatgtgaccacccagaccccattgaccccagagcagctccgggcagtg
gagaacactgtgcaggaggccgtggggcaggatgaggctgtgtacatggaggaggtgccc
ctggcgctcactgcccaggtccctggcctgcgctctctggatgaggtttacccagaccct
gtgcgggtggtatcagtgggggtgcccgtggcccatgcattggacccagcctcccaagcc
gcactgcagacctctgtggagctatgctgtgggacgcacctgttacgtactggggctgta
ggggacctggttatcatcggggaccgccagctttccaagggcactacccgcctgctggcc
gtcactggggagcaggcccagcaggcccgagagctaggccagagcctggcccaggaagtg
aaagcggccactgagcggctgagtctggggagccgggatgtggcggaggcactgaggctg
tccaaggacataggacgactcattgaagctgtggaaactgctgtgatgccccagtggcag
cggcgggagctgctggccacagtgaagatgctgcagcggcgtgccaacactgccatccgt
aagctgcaaatgggacaggctgcaaagaaaactcaggagctgctggagcggcactcgaag
gggcctctgattgtggacacagtctctgctgagtctctctcagtgctggtgaaggtggta
cggcagctgtgtgagcaggcccccagcacgtctgtgctcctactcagcccccagcccatg
gggaaggtgctgtgtgcctgtcaggtggcccagggtgccatgcccaccttcacagcagag
gcctgggcactggcagtgtgcagccacatggggggcaaggcgtggggctcacgagtggtg
gcccaaggcaccggaagcactactgacctggaagctgccctcagtatagcccaaacctat
gccctcagccagctctga
DBGET
integrated database retrieval system
