Homo sapiens (human): 5754
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Entry
5754 CDS
T01001
Symbol
PTK7, CCK-4, CCK4
Name
(RefSeq) protein tyrosine kinase 7 (inactive)
KO
K05127
PTK7 protein tyrosine kinase 7 [EC:
2.7.10.1
]
Organism
hsa
Homo sapiens (human)
Drug target
Cofetuzumab:
D11119
Cofetuzumab pelidotin:
D11118
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
5754 (PTK7)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
5754 (PTK7)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
5754 (PTK7)
Protein kinases [BR:
hsa01001
]
Receptor tyrosine kinases (RTK)
CCK family
5754 (PTK7)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
5754 (PTK7)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ig_3
I-set
PK_Tyr_Ser-Thr
Ig_2
ig
Pkinase
V-set
C2-set_2
Ig_6
BiPBP_C
C1-set
Motif
Other DBs
NCBI-GeneID:
5754
NCBI-ProteinID:
NP_002812
OMIM:
601890
HGNC:
9618
Ensembl:
ENSG00000112655
UniProt:
Q13308
Structure
PDB
PDBj
LinkDB
All DBs
Position
6:43076314..43161715
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AA seq
1070 aa
AA seq
DB search
MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGP
VHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFN
IKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSS
KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYE
EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR
CIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLPEPSVWWEHAG
VRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQD
SQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYR
CMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERAD
GSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPER
TTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSG
RYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAAVAYIIAVL
GLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATN
KRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQ
LDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQ
PLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEY
YHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQ
AGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSKP
NT seq
3213 nt
NT seq
+upstream
nt +downstream
nt
atgggagctgcgcggggatccccggccagaccccgccggttgcctctgctcagcgtcctg
ctgctgccgctgctgggcggtacccagacagccattgtcttcatcaagcagccgtcctcc
caggatgcactgcaggggcgccgggcgctgcttcgctgtgaggttgaggctccgggcccg
gtacatgtgtactggctgctcgatggggcccctgtccaggacacggagcggcgtttcgcc
cagggcagcagcctgagctttgcagctgtggaccggctgcaggactctggcaccttccag
tgtgtggctcgggatgatgtcactggagaagaagcccgcagtgccaacgcctccttcaac
atcaaatggattgaggcaggtcctgtggtcctgaagcatccagcctcggaagctgagatc
cagccacagacccaggtcacacttcgttgccacattgatgggcaccctcggcccacctac
caatggttccgagatgggacccccctttctgatggtcagagcaaccacacagtcagcagc
aaggagcggaacctgacgctccggccagctggtcctgagcatagtgggctgtattcctgc
tgcgcccacagtgcttttggccaggcttgcagcagccagaacttcaccttgagcattgct
gatgaaagctttgccagggtggtgctggcaccccaggacgtggtagtagcgaggtatgag
gaggccatgttccattgccagttctcagcccagccacccccgagcctgcagtggctcttt
gaggatgagactcccatcactaaccgcagtcgccccccacacctccgcagagccacagtg
tttgccaacgggtctctgctgctgacccaggtccggccacgcaatgcagggatctaccgc
tgcattggccaggggcagaggggcccacccatcatcctggaagccacacttcacctagca
gagattgaagacatgccgctatttgagccacgggtgtttacagctggcagcgaggagcgt
gtgacctgccttccccccaagggtctgccagagcccagcgtgtggtgggagcacgcggga
gtccggctgcccacccatggcagggtctaccagaagggccacgagctggtgttggccaat
attgctgaaagtgatgctggtgtctacacctgccacgcggccaacctggctggtcagcgg
agacaggatgtcaacatcactgtggccactgtgccctcctggctgaagaagccccaagac
agccagctggaggagggcaaacccggctacttggattgcctgacccaggccacaccaaaa
cctacagttgtctggtacagaaaccagatgctcatctcagaggactcacggttcgaggtc
ttcaagaatgggaccttgcgcatcaacagcgtggaggtgtatgatgggacatggtaccgt
tgtatgagcagcaccccagccggcagcatcgaggcgcaagcccgtgtccaagtgctggaa
aagctcaagttcacaccaccaccccagccacagcagtgcatggagtttgacaaggaggcc
acggtgccctgttcagccacaggccgagagaagcccactattaagtgggaacgggcagat
gggagcagcctcccagagtgggtgacagacaacgctgggaccctgcattttgcccgggtg
actcgagatgacgctggcaactacacttgcattgcctccaacgggccgcagggccagatt
cgtgcccatgtccagctcactgtggcagtttttatcaccttcaaagtggaaccagagcgt
acgactgtgtaccagggccacacagccctactgcagtgcgaggcccagggggaccccaag
ccgctgattcagtggaaaggcaaggaccgcatcctggaccccaccaagctgggacccagg
atgcacatcttccagaatggctccctggtgatccatgacgtggcccctgaggactcaggc
cgctacacctgcattgcaggcaacagctgcaacatcaagcacacggaggcccccctctat
gtcgtggacaagcctgtgccggaggagtcggagggccctggcagccctcccccctacaag
atgatccagaccattgggttgtcggtgggtgccgctgtggcctacatcattgccgtgctg
ggcctcatgttctactgcaagaagcgctgcaaagccaagcggctgcagaagcagcccgag
ggcgaggagccagagatggaatgcctcaacggtgggcctttgcagaacgggcagccctca
gcagagatccaagaagaagtggccttgaccagcttgggctccggccccgcggccaccaac
aaacgccacagcacaagtgataagatgcacttcccacggtctagcctgcagcccatcacc
acgctggggaagagtgagtttggggaggtgttcctggcaaaggctcagggcttggaggag
ggagtggcagagaccctggtacttgtgaagagcctgcagagcaaggatgagcagcagcag
ctggacttccggagggagttggagatgtttgggaagctgaaccacgccaacgtggtgcgg
ctcctggggctgtgccgggaggctgagccccactacatggtgctggaatatgtggatctg
ggagacctcaagcagttcctgaggatttccaagagcaaggatgaaaaattgaagtcacag
cccctcagcaccaagcagaaggtggccctatgcacccaggtagccctgggcatggagcac
ctgtccaacaaccgctttgtgcataaggacttggctgcgcgtaactgcctggtcagtgcc
cagagacaagtgaaggtgtctgccctgggcctcagcaaggatgtgtacaacagtgagtac
taccacttccgccaggcctgggtgccgctgcgctggatgtcccccgaggccatcctggag
ggtgacttctctaccaagtctgatgtctgggccttcggtgtgctgatgtgggaagtgttt
acacatggagagatgccccatggtgggcaggcagatgatgaagtactggcagatttgcag
gctgggaaggctagacttcctcagcccgagggctgcccttccaaactctatcggctgatg
cagcgctgctgggccctcagccccaaggaccggccctccttcagtgagattgccagcgcc
ctgggagacagcaccgtggacagcaagccgtga
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