Homo sapiens (human): 57572
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Entry
57572 CDS
T01001
Symbol
DOCK6, AOS2, ZIR1
Name
(RefSeq) dedicator of cytokinesis 6
KO
K21852
dedicator of cytokinesis protein 6/7/8
Organism
hsa
Homo sapiens (human)
Disease
H01413
Adams-Oliver syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
57572 (DOCK6)
Membrane trafficking [BR:
hsa04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
57572 (DOCK6)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DHR-2_Lobe_A
DOCK-C2
DHR-2_Lobe_C
DOCK_C-D_N
DHR-2_Lobe_B
Motif
Other DBs
NCBI-GeneID:
57572
NCBI-ProteinID:
NP_065863
OMIM:
614194
HGNC:
19189
Ensembl:
ENSG00000130158
UniProt:
Q96HP0
B7Z9U8
LinkDB
All DBs
Position
19:complement(11199295..11262524)
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AA seq
2047 aa
AA seq
DB search
MAASERRAFAHKINRTVAAEVRKQVSRERSGSPHSSRRCSSSLGVPLTEVVEPLDFEDVL
LSRPPDAEPGPLRDLVEFPADDLELLLQPRECRTTEPGIPKDEKLDAQVRAAVEMYIEDW
VIVHRRYQYLSAAYSPVTTDTQRERQKGLPRQVFEQDASGDERSGPEDSNDSRRGSGSPE
DTPRSSGASSIFDLRNLAADSLLPSLLERAAPEDVDRRNETLRRQHRPPALLTLYPAPDE
DEAVERCSRPEPPREHFGQRILVKCLSLKFEIEIEPIFGILALYDVREKKKISENFYFDL
NSDSMKGLLRAHGTHPAISTLARSAIFSVTYPSPDIFLVIKLEKVLQQGDISECCEPYMV
LKEVDTAKNKEKLEKLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSSAGQLDRDSDSEGE
RRPAWTDRRRRGPQDRASSGDDACSFSGFRPATLTVTNFFKQEAERLSDEDLFKFLADMR
RPSSLLRRLRPVTAQLKIDISPAPENPHFCLSPELLHIKPYPDPRGRPTKEILEFPAREV
YAPHTSYRNLLYVYPHSLNFSSRQGSVRNLAVRVQYMTGEDPSQALPVIFGKSSCSEFTR
EAFTPVVYHNKSPEFYEEFKLHLPACVTENHHLLFTFYHVSCQPRPGTALETPVGFTWIP
LLQHGRLRTGPFCLPVSVDQPPPSYSVLTPDVALPGMRWVDGHKGVFSVELTAVSSVHPQ
DPYLDKFFTLVHVLEEGAFPFRLKDTVLSEGNVEQELRASLAALRLASPEPLVAFSHHVL
DKLVRLVIRPPIISGQIVNLGRGAFEAMAHVVSLVHRSLEAAQDARGHCPQLAAYVHYAF
RLPGTEPSLPDGAPPVTVQAATLARGSGRPASLYLARSKSISSSNPDLAVAPGSVDDEVS
RILASKLLHEELALQWVVSSSAVREAILQHAWFFFQLMVKSMALHLLLGQRLDTPRKLRF
PGRFLDDITALVGSVGLEVITRVHKDVELAEHLNASLAFFLSDLLSLVDRGFVFSLVRAH
YKQVATRLQSSPNPAALLTLRMEFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTSQ
SSTFSSQAPDPKVTSMFELSGPFRQQHFLAGLLLTELALALEPEAEGAFLLHKKAISAVH
SLLCGHDTDPRYAEATVKARVAELYLPLLSIARDTLPRLHDFAEGPGQRSRLASMLDSDT
EGEGDIAGTINPSVAMAIAGGPLAPGSRASISQGPPTASRAGCALSAESSRTLLACVLWV
LKNTEPALLQRWATDLTLPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFKKSLDMKAR
LEEAILGTIGARQEMVRRSRERSPFGNPENVRWRKSVTHWKQTSDRVDKTKDEMEHEALV
EGNLATEASLVVLDTLEIIVQTVMLSEARESVLGAVLKVVLYSLGSAQSALFLQHGLATQ
RALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRTHASASLYLLMRQNFEIGHNFA
RVKMQVTMSLSSLVGTTQNFSEEHLRRSLKTILTYAEEDMGLRDSTFAEQVQDLMFNLHM
ILTDTVKMKEHQEDPEMLIDLMYRIARGYQGSPDLRLTWLQNMAGKHAELGNHAEAAQCM
VHAAALVAEYLALLEDHRHLPVGCVSFQNISSNVLEESAISDDILSPDEEGFCSGKHFTE
LGLVGLLEQAAGYFTMGGLYEAVNEVYKNLIPILEAHRDYKKLAAVHGKLQEAFTKIMHQ
SSGWERVFGTYFRVGFYGAHFGDLDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVE
IIKDSNPVDKSKLDSQKAYIQITYVEPYFDTYELKDRVTYFDRNYGLRTFLFCTPFTPDG
RAHGELPEQHKRKTLLSTDHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELAFAT
EQDPPDAKMLQMVLQGSVGPTVNQGPLEVAQVFLAEIPEDPKLFRHHNKLRLCFKDFCKK
CEDALRKNKALIGPDQKEYHRELERNYCRLREALQPLLTQRLPQLMAPTPPGLRNSLNRA
SFRKADL
NT seq
6144 nt
NT seq
+upstream
nt +downstream
nt
atggctgcctccgagcgccgcgccttcgcgcacaagatcaacaggacggtggccgcagag
gtgcggaagcaggtgtcccgggaacgcagtggctccccccactccagcaggcgctgcagc
agctccctgggggtcccactgactgaagttgtcgagcccctggactttgaggatgtactt
ctgagccggccaccagatgctgagcccgggcccctcagggacctggtagaattcccagct
gatgacttggagctgctgctgcagccccgggaatgccggaccacggagcccgggatcccc
aaggatgaaaaactggatgcccaggtgagggccgcggtggagatgtatattgaggactgg
gtcattgtccacagaaggtatcagtacctgagtgcagcatacagccccgtcaccacagac
acacagcgggagcgacagaagggcctcccccgccaggtctttgagcaggatgcttctgga
gacgagaggtccggccctgaggactcgaatgactcccggcgtggctcgggctccccggaa
gacacccctcgaagcagtggtgcctctagcatcttcgacctgaggaacctggcagctgac
tcattgctgccctctctgctagagcgggcggccccagaagatgtggaccggcgcaatgaa
acccttcgacggcagcaccggcccccggccctgctcaccctctacccggcacctgacgag
gatgaagccgtggaacgctgtagccgcccagagccaccccgcgagcactttggacaaagg
atcttggtcaagtgtctgtcgctcaagttcgagattgaaattgagcccatctttgggatc
ttggctctgtatgatgtgcgggagaaaaagaagatctcggagaacttctacttcgacctg
aactcggactccatgaaggggctgcttcgggctcatggcacccaccctgccatctccacc
ctggcccgctctgccatcttctctgtgacctacccctcacctgacatcttcctggtcatc
aagttggagaaggtgcttcagcaaggggacatcagtgagtgctgtgagccttacatggtg
ttgaaagaagtggacacagccaagaacaaagagaagctagagaagctgcgcctggcggcc
gagcagttctgcacccgcctgggccgctaccgcatgcccttcgcctggacggccgtgcac
ttggccaacatcgtgagcagcgctgggcagctggaccgggactctgactcggagggcgag
cgccggccagcctggacagaccgccgccgtcgggggccccaggaccgggcgagtagtggg
gacgacgcctgcagcttctctggcttccgtccagccacgctaactgtcacaaacttcttt
aagcaggaggctgagcgactcagtgacgaggacctcttcaagttcctggctgacatgagg
cgcccgtcgtccctgctgcggcgactacgtcctgtgactgcccagctcaagatcgacatt
tctccggctcctgaaaatccccacttctgcctctcccctgagctgcttcatatcaagccc
tacccggaccccaggggccggcccaccaaggagattctggagttccccgcccgcgaagtc
tatgccccccataccagctacaggaacctgctgtacgtgtacccgcacagcctcaacttc
agcagccgccagggctccgtgcgcaaccttgctgtgcgagtgcagtacatgacaggcgag
gaccccagccaggctctgccggtcatctttggcaagtccagctgcagtgaatttacccgc
gaggccttcacaccggtggtctaccataacaagtcccccgagttctacgaggagttcaag
ctgcatcttccagcctgcgtgacagagaaccatcacctgctgttcaccttctaccatgtc
agctgccagccccggccgggcactgccctggagacacccgtgggctttacttggatccca
ctgctgcagcacgggcgcctgaggaccggccccttctgtctcccagtgtctgtggaccag
ccgccgcccagctattccgtgctcacacccgatgtggcgcttccgggcatgcgctgggtg
gacggtcacaagggcgtgttcagtgtggagctcacagccgtgtcctctgtgcacccccag
gacccctacctggacaaattcttcaccctggtgcacgtcctggaggagggagccttccca
ttccggctcaaggacactgtgctgagcgagggcaacgtggagcaggagctgcgggccagt
cttgcagcactgcgcctggccagccccgaaccccttgtggccttctcccaccacgtgctg
gacaagctcgtgcgtctggtcatcaggcccccgatcatcagtggccagattgtgaacctg
ggccgtggagcctttgaagcaatggcccatgtagtcagccttgttcaccggagcctggag
gcagcccaggatgcccgcggtcactgcccacagctggctgcctacgtccactacgccttt
cgccttcctggcactgagcccagcctcccggatggggcccctccagtgacagtgcaggct
gccacactggcccgtggctctggtcgccccgcaagcctctacctggcgcgttccaagagc
atcagcagcagcaaccctgacctcgccgtggcccctggctctgtggatgacgaggtttcc
cgcatcctggccagcaagctgcttcacgaggagctggctctgcagtgggtggtcagcagc
agtgccgtacgcgaggccatcctccagcacgcctggttcttcttccagctcatggtgaag
agtatggcgctgcacctgctgcttggccagcgactagacacaccccgcaagctgcgcttc
cccggacgcttcctggacgacatcactgccttggtgggctctgtgggcctggaggtcatc
acccgtgtccacaaggatgtggagctggccgagcacctcaacgccagcctggctttcttc
ctcagtgaccttctgtccctggtggaccggggctttgtcttcagcctggtccgggcccac
tacaagcaggtggccacgcggctccagtcgtcccctaatccagcagccctgctgaccctg
cgcatggaattcacccgcatcctgtgcagccacgagcactacgtgaccctcaacctcccc
tgctgccccctgtcacctccagcctcgccctccccctctgtgtcctccaccacctcccag
agctccaccttctccagccaagccccggaccccaaggtgaccagcatgttcgaactgagt
ggaccattccggcagcagcacttcctagctgggctcctgctgacggagctggcactggcc
ctcgaacctgaggctgaaggggcattcctgttgcacaagaaggccatcagtgctgtgcac
agcctgctatgtggccatgacactgacccccgctacgccgaggccactgtgaaggctcgt
gtggccgagctgtacctgccactgctatcgattgcacgggataccttgccacggctgcat
gactttgctgagggcccaggtcagcggtcaagactggcctcaatgcttgactcagacaca
gaaggcgaaggggacattgcgggtaccatcaacccctctgtggccatggccattgctggt
ggccccctagcccctggctcccgggccagcatctcccaggggccaccaacggcttctcgc
gcaggctgtgccctctctgctgagtcaagccggaccttgctggcgtgtgtgctgtgggtg
ctgaaaaacaccgagccggcgctcctgcagcgctgggccactgacctgacactcccccag
ctgggacgtctgttggatttgctgtacctttgcctagctgcctttgagtacaaggggaaa
aaggcctttgaacgcatcaacagcctcacattcaaaaaatctctggatatgaaggcgcgg
ctagaggaagccattctgggtaccatcggagctcgacaagaaatggttcggcgaagtcgt
gagaggagcccgtttgggaatccggagaatgtgcgctggcggaagagcgtcacacactgg
aagcaaacctcagaccgcgtggacaagaccaaggatgaaatggaacacgaggccttggtg
gaagggaacctggcaaccgaggcaagcctagtggttctggacacactggagatcatcgtg
cagacggtgatgctttcagaagcccgggagagcgtcttgggggcagtgctgaaggttgtg
ctgtacagcctgggcagtgcccagagtgccctcttcttgcagcatggcctggccacccag
agggcccttgtgtccaagttcccggagctgctgttcgaggaggacacggagctgtgtgcc
gacctgtgcctgaggctcctacgacactgtggcagccgcatcagcaccatccgcacgcac
gccagcgcctcgctgtacctgctcatgcgacagaacttcgagatcggccacaactttgcc
cgtgtgaagatgcaggtcaccatgtctctctcgtccctggtggggacgacgcagaacttc
agtgaagagcacctgcgacgttcactcaaaaccatcctcacctatgctgaggaggacatg
gggctgcgggacagcaccttcgcagagcaggtccaggacctgatgttcaacctgcacatg
atcctgacggacacggtgaagatgaaggaacaccaggaggaccctgagatgctcatcgac
ctcatgtacagaattgcccggggctaccagggctcaccggaccttcggctgacctggttg
cagaacatggccgggaagcacgcggagctgggcaaccacgccgaggccgcccagtgcatg
gtgcacgcggccgccctcgtggctgagtacctcgccctgctcgaggaccaccgccacctg
cccgtgggctgcgtttccttccagaacatctcatccaacgtgctagaggagtccgccatc
tccgacgacatcctgtcgcccgacgaggagggcttctgctccgggaagcacttcactgag
ctggggctggtagggttgctggaacaggcagccggctacttcaccatgggcgggctctac
gaggcggtgaatgaggtctacaagaacctcatccccatcctggaagcccaccgtgactac
aagaagctggccgcggtgcacggcaaactgcaggaggccttcaccaagatcatgcaccag
agttccggctgggagcgcgtgttcgggacgtatttccgcgtgggcttctacggcgcccac
ttcggtgacctggatgagcaggagtttgtgtacaaggagccatcgatcacgaagctggca
gagatctcacaccggctggaggagttctacacggagagatttggcgacgacgtcgttgag
attatcaaagactctaaccctgtggacaagtccaagcttgactcacaaaaggcctacatc
cagatcacgtatgtggaaccgtactttgatacctacgagctcaaggaccgggtgacctac
tttgaccgcaactatgggcttcgcacattcctgttctgcacgccgttcacgccggatggg
cgcgcacacggggagctgcccgagcaacacaagcgtaagacgctgctcagcaccgaccac
gccttcccctacatcaagactcgcatccgtgtgtgccaccgggaggagacggtgctgacg
ccagtggaggtggccatcgaggacatgcagaagaagacacgggagctggcctttgccacc
gagcaggacccaccagatgctaagatgctacagatggtgcttcagggctctgtagggccc
accgtgaaccagggtcccctggaggtggcccaggtgtttttagcagagatcccggaagac
cccaagctcttccggcatcacaacaaattgcggctctgcttcaaggacttctgcaagaaa
tgtgaggatgcgctgcggaaaaataaggccctgattgggccggaccagaaggagtaccac
cgtgagctggagcgcaactactgccgcctgcgggaggctctgcagcccctgcttacccag
cgcctgccccagctgatggcacccaccccacccggcctcaggaactccttgaacagagca
agtttccgaaaggcagacctctga
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integrated database retrieval system
