Homo sapiens (human): 57647
Help
Entry
57647 CDS
T01001
Symbol
DHX37, DDX37, Dhr1, NEDBAVC, SRXY11
Name
(RefSeq) DEAH-box helicase 37
KO
K14780
ATP-dependent RNA helicase DHX37/DHR1 [EC:
5.6.2.6
]
Organism
hsa
Homo sapiens (human)
Disease
H00607
46,XY gonadal dysgenesis
H02470
Neurodevelopmental disorder with structural brain abnormalities
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03009 Ribosome biogenesis [BR:
hsa03009
]
57647 (DHX37)
Enzymes [BR:
hsa01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.6 RNA 3'-5' helicase
57647 (DHX37)
Ribosome biogenesis [BR:
hsa03009
]
Eukaryotic type
90S particles
Helicases
57647 (DHX37)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DHX37_C
OB_NTP_bind
HA2_C
DEAD
Helicase_C
AAA_22
HA2_N
AAA_19
ResIII
AAA_30
nSTAND3
ATPase
T2SSE
Herpes_ori_bp
Flavi_DEAD
AAA_23
Motif
Other DBs
NCBI-GeneID:
57647
NCBI-ProteinID:
NP_116045
OMIM:
617362
HGNC:
17210
Ensembl:
ENSG00000150990
UniProt:
Q8IY37
Structure
PDB
PDBj
LinkDB
All DBs
Position
12:complement(124946826..124989131)
Genome browser
AA seq
1157 aa
AA seq
DB search
MGKLRRRYNIKGRQQAGPGPSKGPPEPPPVQLELEDKDTLKGVDASNALVLPGKKKKKTK
APPLSKKEKKPLTKKEKKVLQKILEQKEKKSQRAEMLQKLSEVQASEAEMRLFYTTSKLG
TGNRMYHTKEKADEVVAPGQEKISSLSGAHRKRRRWPSAEEEEEEEEESESELEEESELD
EDPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPPAAAPPLPRALAKPAVFIPVN
RSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDSI
IGVTEPRRVAAVAMSQRVAKEMNLSQRVVSYQIRYEGNVTEETRIKFMTDGVLLKEIQKD
FLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVEDFTQNP
RLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVFLTGQA
EVHALCRRLRKAFPPSRARPQEKDDDQKDSVEEMRKFKKSRARAKKARAEVLPQINLDHY
SVLPAGEGDEDREAEVDEEEGALDSDLDLDLGDGGQDGGEQPDASLPLHVLPLYSLLAPE
KQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWV
SQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLILQMKALNVEKV
INFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCPITALGRTMATFPV
APRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDEELTRLKSKRARVAQMK
RTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEANGLRYKAMMEIRRLRGQLTTAVN
AVCPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARRVQSEEMLEDKWRNAYKTPLL
DDPVFIHPSSVLFKELPEFVVYQEIVETTKMYMKGVSSVEVQWIPALLPSYCQFDKPLEE
PAPTYCPERGRVLCHRASVFYRVGWPLPAIEVDFPEGIDRYKHFARFLLEGQVFRKLASY
RSCLLSSPGTMLKTWARLQPRTESLLRALVAEKADCHEALLAAWKKNPKYLLAEYCEWLP
QAMHPDIEKAWPPTTVH
NT seq
3474 nt
NT seq
+upstream
nt +downstream
nt
atggggaagctgcgccggcgctacaacatcaaggggcgccagcaggcgggccccggaccc
tcgaagggcccccccgagccgccccccgtgcagctggaactggaggacaaggacacgttg
aagggagttgatgcaagcaacgcgctcgttctaccggggaagaagaaaaagaagaccaaa
gcccctcccctgtcgaagaaggagaagaagcctctgaccaagaaggagaagaaagtgctg
cagaaaatcttagaacagaaggagaaaaagagccagcgagcagagatgctacagaagctg
agtgaagtccaggcttccgaagctgagatgagactcttttataccacttccaagctaggc
actgggaaccgcatgtatcacaccaaagagaaggctgacgaggtggtagccccgggccag
gagaagatcagtagcctcagcggtgcccaccggaagcgtcgccgctggccctcagctgag
gaggaggaggaggaggaggaggagtcggaatcggagctggaggaggagtcggagctggac
gaggacccagctgctgagccggctgaggctggtgtggggaccaccgtggcacctctgccg
ccagctccagcacccagcagtcagcccgtgccggctgggatgactgttcctcctcctcca
gctgcagccccaccactgcccagggccctggctaagcccgccgtcttcatccccgtgaac
cgctccccggaaatgcaggaggaacggctgaagctcccaattctctccgaagaacaagta
atcatggaggctgtggccgagcaccccatcgtcatcgtgtgtggtgagaccggcagcggg
aagaccacacaggtgcctcagtttctctatgaagcaggcttcagcagtgaagacagcatc
atcggtgtcacggagccccgccgagtggccgccgtggccatgtcccagcgagtggccaag
gagatgaatctgtcccagcgggtcgtctcctaccagatccggtatgaaggaaacgtgaca
gaggagaccagaatcaagttcatgacggatggtgtgctgcttaaagaaatccagaaggac
ttcctgctgctgcggtacaaggtggtgatcatcgacgaggcccacgagaggagcgtgtac
acggacatcctcatcggcctcctgtcccgcattgtgactctccgggctaagaggaacctg
ccactcaagctgctcatcatgtcggccacgctgcgggtggaggacttcacccagaaccca
cggctcttcgccaagccgccgccggtcatcaaggtggaatccaggcagttcccagtgact
gtgcatttcaacaagcggacaccgctggaagactacagtggcgagtgcttccggaaggtc
tgcaagatccaccggatgctgcccgcaggtggcatcctggtgttcctgacggggcaggct
gaggtgcatgcgctgtgccgcaggctcaggaaggctttcccaccctccagagcccggcca
caagaaaaggacgacgatcagaaagactcggtggaggaaatgcggaagtttaagaagtca
agggccagggccaagaaggcgcgggctgaggtgctgccccagatcaacttggatcattac
tcggtgttaccggcaggcgaaggcgatgaggacagggaggcagaagtggatgaggaagag
ggggccctggactccgacctcgatctggacctgggggatggcgggcaagatggaggtgag
cagccggatgcctccctcccgctccacgtgctcccgctgtactctctgctggccccagag
aagcaagcacaggtctttaagcctccaccggaggggactcggttgtgtgttgtggccacc
aatgtggccgagacgtcgcttaccatccctggcatcaagtacgtggtggactgtgggaag
gtcaagaaacgctactacgaccgcgtcactggcgtatcctccttccgtgtcacctgggtc
tcccaggcatcagctgaccagcgagcgggcagagcaggacggacggagcccggccactgc
tacaggctgtattcatctgcggtttttggtgacttcgagcagtttcctcctccagaaatc
acccggaggcctgttgaagacttaatccttcaaatgaaggcgctcaacgttgaaaaggtc
atcaacttccccttcccgacgcccccctccgtggaagcccttcttgccgccgaggagctg
ttgatcgcactgggtgccctgcaaccgccccagaaagcagaaagggtgaagcaactgcag
gagaaccggctgagctgccccatcactgcgctgggccggacaatggccacattccccgtg
gcaccccgctacgctaagatgctggcactgagccgacaacacggctgcctgccctatgcc
atcaccatcgtggccagcatgacggtgcgggagctgtttgaggagctggacagaccagcg
gccagtgacgaggagctcaccaggctgaagagcaagcgggcccgggtggcccagatgaag
aggacctgggcagggcagggggcttctctgaagctcggcgacctcatggtgctgctgggc
gccgtgggagcctgtgagtatgccagctgcacaccccagttttgcgaagccaacgggctg
cggtacaaagccatgatggagatccggcgcctgcggggccagctgaccaccgcagtcaat
gccgtgtgccccgaggctgagctcttcgtggatcccaagatgcagccgcccaccgagagc
caggtgacctacctgcgacagatcgtgacggcaggcctgggggaccacttggcccgcagg
gtccagagcgaggagatgctggaggacaagtggaggaacgcctacaagacccctctcctc
gacgaccctgtcttcatccaccccagctccgtccttttcaaagagctccccgagtttgtg
gtctaccaggaaatcgtggagaccactaagatgtacatgaaaggcgtctctagcgtggag
gtccagtggatcccggccctgctgccctcttactgccagtttgacaagcccctggaggaa
ccagcccctacatactgccccgagcgggggcgggtgctgtgtcaccgggccagcgtgttc
tatcgcgtgggctggccgctccccgccatcgaggtggattttccagaggggattgaccgc
tacaagcactttgcccggttcctgctggaagggcaggtcttccgcaagctggcctcatac
cggagctgtctgctgtccagccccggcaccatgctgaagacgtgggccaggctgcagccc
cgtacggagagccttctgcgagccctggttgcagagaaggctgactgccatgaagccttg
ctggctgcttggaagaaaaaccccaaatacctgctggctgagtactgtgagtggcttcca
caggccatgcaccccgatatcgagaaagcctggccccccaccactgtccactga
DBGET
integrated database retrieval system
