Homo sapiens (human): 5771
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Entry
5771 CDS
T01001
Symbol
PTPN2, PTN2, PTPT, TC-PTP, TC45, TC48, TCELLPTP, TCPTP
Name
(RefSeq) protein tyrosine phosphatase non-receptor type 2
KO
K18026
tyrosine-protein phosphatase non-receptor type 2 [EC:
3.1.3.48
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04630
JAK-STAT signaling pathway
Disease
H00408
Type 1 diabetes mellitus
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
5771 (PTPN2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
5771 (PTPN2)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
5771 (PTPN2)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
5771 (PTPN2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
PTP-SAK
DSPc
Synaptobrevin
Tc-R-P
IKKbetaNEMObind
CHASE3
Motif
Other DBs
NCBI-GeneID:
5771
NCBI-ProteinID:
NP_002819
OMIM:
176887
HGNC:
9650
Ensembl:
ENSG00000175354
UniProt:
P17706
Q59F91
Structure
PDB
PDBj
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All DBs
Position
18:complement(12785478..12884237)
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AA seq
415 aa
AA seq
DB search
MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK
LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES
VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW
PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD
DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA
FDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKAT
TAQKVQQMKQRLNENERKRKRWLYWQPILTKMGFMSVILVGAFVGWTLFFQQNAL
NT seq
1248 nt
NT seq
+upstream
nt +downstream
nt
atgcccaccaccatcgagcgggagttcgaagagttggatactcagcgtcgctggcagccg
ctgtacttggaaattcgaaatgagtcccatgactatcctcatagagtggccaagtttcca
gaaaacagaaatcgaaacagatacagagatgtaagcccatatgatcacagtcgtgttaaa
ctgcaaaatgctgagaatgattatattaatgccagtttagttgacatagaagaggcacaa
aggagttacatcttaacacagggtccacttcctaacacatgctgccatttctggcttatg
gtttggcagcagaagaccaaagcagttgtcatgctgaaccgcattgtggagaaagaatcg
gttaaatgtgcacagtactggccaacagatgaccaagagatgctgtttaaagaaacagga
ttcagtgtgaagctcttgtcagaagatgtgaagtcgtattatacagtacatctactacaa
ttagaaaatatcaatagtggtgaaaccagaacaatatctcactttcattatactacctgg
ccagattttggagtccctgaatcaccagcttcatttctcaatttcttgtttaaagtgaga
gaatctggctccttgaaccctgaccatgggcctgcggtgatccactgtagtgcaggcatt
gggcgctctggcaccttctctctggtagacacttgtcttgttttgatggaaaaaggagat
gatattaacataaaacaagtgttactgaacatgagaaaataccgaatgggtcttattcag
accccagatcaactgagattctcatacatggctataatagaaggagcaaaatgtataaag
ggagattctagtatacagaaacgatggaaagaactttctaaggaagacttatctcctgcc
tttgatcattcaccaaacaaaataatgactgaaaaatacaatgggaacagaataggtcta
gaagaagaaaaactgacaggtgaccgatgtacaggactttcctctaaaatgcaagataca
atggaggagaacagtgagagtgctctacggaaacgtattcgagaggacagaaaggccacc
acagctcagaaggtgcagcagatgaaacagaggctaaatgagaatgaacgaaaaagaaaa
aggtggttatattggcaacctattctcactaagatggggtttatgtcagtcattttggtt
ggcgcttttgttggctggacactgttttttcagcaaaatgccctataa
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