Homo sapiens (human): 5787
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Entry
5787 CDS
T01001
Symbol
PTPRB, HPTP-BETA, HPTPB, PTPB, R-PTP-BETA, VEPTP
Name
(RefSeq) protein tyrosine phosphatase receptor type B
KO
K05694
receptor-type tyrosine-protein phosphatase beta [EC:
3.1.3.48
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04520
Adherens junction
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
5787 (PTPRB)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
5787 (PTPRB)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
5787 (PTPRB)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Receptor PTPs
5787 (PTPRB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
fn3
Y_phosphatase
Ig_ILCR1
FN3_Tor_3rd
Fn3_Dep-1_4th
PTP_tm
Tc-R-P
PTP-SAK
PTP-NADK
DSPc
Fn3_ELFN
Y_phosphatase3
Glyco_hydro_66
PTPlike_phytase
CR_prot_dom_plant
Motif
Other DBs
NCBI-GeneID:
5787
NCBI-ProteinID:
NP_002828
OMIM:
176882
HGNC:
9665
Ensembl:
ENSG00000127329
UniProt:
P23467
Structure
PDB
PDBj
LinkDB
All DBs
Position
12:complement(70515870..70637429)
Genome browser
AA seq
1997 aa
AA seq
DB search
MLSHGAGLALWITLSLLQTGLAEPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSS
DTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERTVVLQTDPLPPARFGVSK
EKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYN
IAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKG
ILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTND
GSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSC
VSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFNDSVVLL
NITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVPLAVLQLRVKHANE
TSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISG
DLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNES
ISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYL
SVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYE
NHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPK
SENECVFVQLVPGRLYSVTVTTKSGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWS
GANGDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAF
IEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFE
HTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAA
GVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTE
GRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFS
FQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASGD
FDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAESRTA
PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVY
GLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDS
DFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDS
TITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDE
LKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNSNSKSFNIKLGAEMESLGGKCD
PTQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAI
EGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTS
CPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYD
ATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVM
VTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLI
RHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRI
LQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPI
YENVNPEYHRDPVYSRH
NT seq
5994 nt
NT seq
+upstream
nt +downstream
nt
atgctgagccatggagccgggttggccttgtggatcacactgagcctgctgcagactgga
ctggcggagccagagagatgtaacttcaccctggcggagtccaaggcctccagccattct
gtgtctatccagtggagaattttgggctcaccctgtaactttagcctcatctatagcagt
gacaccctgggggccgcgttgtgccctacctttcggatagacaacaccacatacggatgt
aaccttcaagatttacaagcaggaaccatctataacttcaggattatttctctggatgaa
gagagaacagtggtcttgcaaacagatcctttacctcctgctaggtttggagtcagtaaa
gagaagacgacttcaaccagcttgcatgtttggtggactccttcttccggaaaagtcacc
tcatatgaggtgcaattatttgatgaaaataaccaaaagatacagggggttcaaattcaa
gaaagtacttcatggaatgaatacacttttttcaatctcactgctggtagtaaatacaat
attgccatcacagctgtttctggaggaaaacgttctttttcagtttataccaatggatca
acagtgccatctccagtgaaagatattggtatttccacaaaagccaattctctcctgatt
tcctggtcccatggttctgggaatgtggaacgataccggctgatgctaatggataaaggg
atcctagttcatggcggtgttgtggacaaacatgctacttcctatgcttttcacgggctg
acccctggctacctctacaacctcactgttatgactgaggctgcagggctgcaaaactac
aggtggaaactagtcaggacagcccccatggaagtctcaaatctgaaggtgacaaatgat
ggcagtttgacctctctaaaagtcaaatggcaaagacctcctggaaatgtggattcttac
aatatcaccctgtctcacaaagggaccatcaaggaatccagagtattagcaccttggatt
actgaaactcactttaaagagttagtccccggtcgactttatcaagttactgtcagctgt
gtctctggtgaactgtctgctcagaagatggcagtgggcagaacatttccagacaaagtt
gcaaacctggaggcaaacaataatggcaggatgaggtctcttgtagtgagctggtcgccc
cctgctggagactgggagcagtatcggatcctactcttcaatgattctgtggtgctgctc
aacatcactgtgggaaaggaagaaacacagtatgtcatggatgacacggggctcgtaccg
ggaagacagtatgaggtggaagtcattgttgagagtggaaatttgaagaattctgagcgt
tgccaaggcaggacagtccccctggctgtcctccagcttcgtgtcaaacatgccaatgaa
acctcactgagtatcatgtggcagacccctgtagcagaatgggagaaatacatcatttcc
ctagctgacagagacctcttactgatccacaagtcactctccaaagatgccaaagaattc
acttttactgacctggtgcctggacgaaaatacatggctacagtcaccagtattagtgga
gacttaaaaaattcctcttcagtaaaaggaagaacagtgcctgcccaagtgactgacttg
catgtggccaaccaaggaatgaccagtagtctgtttactaactggacccaggcacaagga
gacgtagaattttaccaagtcttactgatccatgaaaatgtggtcattaaaaatgaaagc
atctccagtgagaccagcagatacagcttccactctctcaagtccggcagcctgtactcc
gtggtggtaacaacagtgagtggagggatctcttcccgacaagtggttgtggagggaaga
acagtcccttccagtgtgagtggagtaacggtgaacaattccggtcgtaatgactacctc
agcgtttcctggctgctggcgcccggagatgtggataactatgaggtaacattgtctcat
gacggcaaggtggttcagtcccttgtcattgccaagtctgtcagagaatgttccttcagc
tccctcaccccaggccgcctctacaccgtgaccataactacaaggagtggcaagtatgaa
aatcactccttcagccaagagcggacagtgcctgacaaagtccagggagtcagtgttagc
aactcagccaggagtgactatttaagggtatcctgggtgcatgccactggagactttgat
cactatgaagtcaccattaaaaacaaaaacaacttcattcaaactaaaagcattcccaag
tcagaaaacgaatgtgtatttgttcagctagtccctggacggttgtacagtgtcactgtt
actacaaaaagtggacaatatgaagccaatgaacaagggaatgggagaacaattccagag
cctgttaaggatctaacattgcgcaacaggagcactgaggacttgcatgtgacttggtca
ggagctaatggggatgtcgaccaatatgagatccagctgctcttcaatgacatgaaagta
tttcctccttttcaccttgtaaataccgcaaccgagtatcgatttacttccctaacacca
ggccgccaatacaaaattcttgtcttgacgattagcggggatgtacagcagtcagccttc
attgagggcttcacagttcctagtgctgtcaaaaatattcacatttctcccaatggagca
acagatagcctgacggtgaactggactcctggtgggggagacgttgattcctacacggtg
tcggcattcaggcacagtcaaaaggttgactctcagactattcccaagcacgtctttgag
cacacgttccacagactggaggccggggagcagtaccagatcatgattgcctcagtcagc
gggtccctgaagaatcagataaatgtggttgggcggacagttccagcatctgtccaagga
gtaattgcagacaatgcatacagcagttattccttaatagtaagttggcaaaaagctgct
ggtgtggcagaaagatatgatatcctgcttctaactgaaaatggaatccttctgcgcaac
acatcagagccagccaccactaagcaacacaaatttgaagatctaacaccaggcaagaaa
tacaagatacagatcctaactgtcagtggaggcctctttagcaaggaagcccagactgaa
ggccgaacagtcccagcagctgtcaccgacctgaggatcacagagaactccaccaggcac
ctgtccttccgctggaccgcctcagagggggagctcagctggtacaacatctttttgtac
aacccagatgggaatctccaggagagagctcaagttgacccactagtccagagcttctct
ttccagaacttgctacaaggcagaatgtacaagatggtgattgtaactcacagtggggag
ctgtctaatgagtctttcatatttggtagaacagtcccagcctctgtgagtcatctcagg
gggtccaatcggaacacgacagacagcctttggttcaactggagtccagcctctggggac
tttgacttttatgagctgattctctataatcccaatggcacaaagaaggaaaactggaaa
gacaaggacctgacggagtggcggtttcaaggccttgttcctggaaggaagtacgtgctg
tgggtggtaactcacagtggagatctcagcaataaagtcacagcggagagcagaacagct
ccaagtcctcccagtcttatgtcatttgctgacattgcaaacacatccttggccatcacg
tggaaagggcccccagactggacagactacaacgactttgagctgcagtggttgcccaga
gatgcacttactgtcttcaacccctacaacaacagaaaatcagaaggacgcattgtgtat
ggtcttcgtccagggagatcctatcaattcaacgtcaagactgtcagtggtgattcctgg
aaaacttacagcaaaccaatttttggatctgtgaggacaaagcctgacaagatacaaaac
ctgcattgccggcctcagaactccacggccattgcctgttcttggatccctcctgattct
gactttgatggttatagtattgaatgccggaaaatggacacccaagaagttgagttttcc
agaaagctggagaaagaaaaatctctgctcaacatcatgatgctagtgccccataagagg
tacctggtgtccatcaaagtgcagtcggccggcatgaccagcgaggtggttgaagacagc
actatcacaatgatagaccgcccccctcctccacccccacacattcgtgtgaatgaaaag
gatgtgctaattagcaagtcttccatcaactttactgtcaactgcagctggttcagcgac
accaatggagctgtgaaatacttcacagtggtggtgagagaggctgatggcagtgatgag
ctgaagccagaacagcagcaccctctcccttcctacctggagtacaggcacaatgcctcc
attcgggtgtatcagactaattattttgccagcaaatgtgccgaaaatcctaacagcaac
tccaagagttttaacattaagcttggagcagagatggagagcctaggtggaaaatgcgat
cccactcagcaaaaattctgtgatggaccactgaagccacacactgcctacagaatcagc
attcgagcttttacacagctctttgatgaggacctgaaggaattcacaaagccactctat
tcagacacatttttttctttacccatcactactgaatcagagcccttgtttggagctatt
gaaggtgtgagtgctggtctgtttttaattggcatgctagtggctgttgttgccttattg
atctgcagacagaaagtgagccatggtcgagaaagaccctctgcccgtctgagcattcgt
agggatcgaccattatctgtccacttaaacctgggccagaaaggtaaccggaaaacttct
tgtccaataaaaataaatcagtttgaagggcatttcatgaagctacaggctgactccaac
taccttctatccaaggaatacgaggagttaaaagacgtgggccgaaaccagtcatgtgac
attgcactcttgccggagaatagagggaaaaatcgatacaacaatatattgccctatgat
gccacgcgagtgaagctctccaatgtagatgatgatccttgctctgactacatcaatgcc
agctacatccctggcaacaacttcagaagagaatacattgtcactcagggaccgcttcct
ggcaccaaggatgacttctggaaaatggtgtgggaacaaaacgttcacaacatcgtcatg
gtgacccagtgtgttgagaagggccgagtaaagtgtgatcattactggccagcggaccag
gattccctctactatggggacctcatcctgcagatgctctcagagtccgtcctgcctgag
tggaccatccgggagtttaagatatgcggtgaggaacagcttgatgcacacagactcatc
cgccactttcactatacggtgtggccagaccatggagtcccagaaaccacccagtctctg
atccagtttgtgagaactgtcagggactacatcaacagaagcccgggtgctgggcccact
gtggtgcactgcagtgctggtgtgggtaggactggaacctttattgcattggaccgaatc
ctccagcagttagactccaaagactctgtggacatttatggagcagtgcacgacctaaga
cttcacagggttcacatggtccagactgagtgtcagtatgtctacctacatcagtgtgta
agagatgtcctcagagcaagaaagctacggagtgaacaagaaaaccccttgtttccaatc
tatgaaaatgtgaatccagagtatcacagagatccagtctattcaaggcattga
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integrated database retrieval system
