KEGG   Homo sapiens (human): 5818
Entry
5818              CDS       T01001                                 
Symbol
NECTIN1, CD111, CLPED1, ED4, HIgR, HV1S, HVEC, OFC7, PRR, PRR1, PVRL1, PVRR, PVRR1, SK-12, nectin-1
Name
(RefSeq) nectin cell adhesion molecule 1
  KO
K06081  poliovirus receptor-related protein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa03266  Virion - Herpesvirus
hsa04514  Cell adhesion molecules
hsa04517  IgSF CAM signaling
hsa04520  Adherens junction
hsa05168  Herpes simplex virus 1 infection
Network
nt06546  IgSF CAM signaling
  Element
N01949  NECTIN1 interanctions
N01951  NECTIN3 interactions
N01952  NECTIN4 interactions
N01953  NECL1 interactions
N01955  CD96 interactions
Disease
H00516  Cleft lip and/or cleft palate
H02456  Ectodermal dysplasia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03266 Virion - Herpesvirus
    5818 (NECTIN1)
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    5818 (NECTIN1)
   04517 IgSF CAM signaling
    5818 (NECTIN1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    5818 (NECTIN1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    5818 (NECTIN1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:hsa04515]
    5818 (NECTIN1)
   04090 CD molecules [BR:hsa04090]
    5818 (NECTIN1)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  Nectin family
   5818 (NECTIN1)
CD molecules [BR:hsa04090]
 Proteins
  5818 (NECTIN1)
SSDB
Motif
Pfam: C2-set_2 V-set Ig_3 Ig_2 ig I-set TM_ErbB1
Other DBs
NCBI-GeneID: 5818
NCBI-ProteinID: NP_002846
OMIM: 600644
HGNC: 9706
Ensembl: ENSG00000110400
UniProt: Q15223
Structure
LinkDB
Position
11:complement(119638098..119729200)
AA seq 517 aa
MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV
KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG
VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP
SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT
LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL
FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGV
AGSILLVLIVVGGIVVALRRRRHTFKGDYSTKKHVYGNGYSKAGIPQHHPPMAQNLQYPD
DSDDEKKAGPLGGSSYEEEEEEEEGGGGGERKVGGPHPKYDEDAKRPYFTVDEAEARQDG
YGDRTLGYQYDPEQLDLAENMVSQNDGSFISKKEWYV
NT seq 1554 nt   +upstreamnt  +downstreamnt
atggctcggatggggcttgcgggcgccgctggacgctggtggggactcgctctcggcttg
accgcattcttcctcccaggcgtccactcccaggtggtccaggtgaacgactccatgtat
ggcttcatcggcacagacgtggttctgcactgcagctttgccaacccgcttcccagcgtg
aagatcacccaggtcacatggcagaagtccaccaatggctccaagcagaacgtggccatc
tacaacccatccatgggcgtgtccgtgctggctccctaccgcgagcgtgtggaattcctg
cggccctccttcaccgatggcactatccgcctctcccgcctggagctggaggatgagggt
gtctacatctgcgagtttgctaccttccctacgggcaatcgagaaagccagctcaatctc
acggtgatggccaaacccaccaattggatagagggtacccaggcagtgcttcgagccaag
aaggggcaggatgacaaggtcctggtggccacctgcacctcagccaatgggaagcctccc
agtgtggtatcctgggaaactcggttaaaaggtgaggcagagtaccaggagatccggaac
cccaatggcacagtgacggtcatcagccgctaccgcctggtgcccagcagggaagcccac
cagcagtccttggcctgcatcgtcaactaccacatggaccgcttcaaggaaagcctcact
ctcaacgtgcagtatgagcctgaggtaaccattgaggggtttgatggcaactggtacctg
cagcggatggacgtgaagctcacctgcaaagctgatgctaaccccccagccactgagtac
cactggaccacgctaaatggctctctccccaagggtgtggaggcccagaacagaaccctc
ttcttcaagggacccatcaactacagcctggcagggacctacatctgtgaggccaccaac
cccatcggtacacgctcaggccaggtggaggtcaatatcacagaattcccctacaccccg
tctcctcccgaacatgggcggcgcgccgggccggtgcccacggccatcattgggggcgtg
gcggggagcatcctgctggtgttgattgtggtcggcgggatcgtggtcgccctgcgtcgg
cgccggcacaccttcaagggtgactacagcaccaagaagcacgtgtatggcaacggctac
agcaaggcaggcatcccccagcaccacccaccaatggcacagaacctgcagtaccccgac
gactcagacgacgagaagaaggccggcccactgggtggaagcagctatgaggaggaggag
gaggaggaggagggcggtggagggggcgagcgcaaggtgggcggcccccaccccaaatat
gacgaggacgccaagcggccctacttcaccgtggatgaggccgaggcccgtcaggacggc
tacggggaccggactctgggctaccagtacgaccctgagcagctggacttggctgagaac
atggtttctcagaacgacgggtctttcatttccaagaaggagtggtacgtgtag

KEGG   Homo sapiens (human): 5817
Entry
5817              CDS       T01001                                 
Symbol
PVR, CD155, HVED, NECL5, Necl-5, PVS, TAGE4
Name
(RefSeq) PVR cell adhesion molecule
  KO
K06539  poliovirus receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa04514  Cell adhesion molecules
hsa04517  IgSF CAM signaling
Network
nt06546  IgSF CAM signaling
  Element
N01951  NECTIN3 interactions
N01955  CD96 interactions
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03263 Virion - Enterovirus
    5817 (PVR)
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    5817 (PVR)
   04517 IgSF CAM signaling
    5817 (PVR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:hsa04515]
    5817 (PVR)
   04090 CD molecules [BR:hsa04090]
    5817 (PVR)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  Nectin family
   5817 (PVR)
CD molecules [BR:hsa04090]
 Proteins
  5817 (PVR)
SSDB
Motif
Pfam: C2-set_2 Ig_3 ig V-set I-set Ig_2
Other DBs
NCBI-GeneID: 5817
NCBI-ProteinID: NP_006496
OMIM: 173850
HGNC: 9705
Ensembl: ENSG00000073008
UniProt: P15151 A0A0C4DG49 A8K4I1
Structure
LinkDB
Position
19:44643910..44666162
AA seq 417 aa
MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH
VSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN
YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH
SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV
YYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIR
PVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGMSRNAIIFLVLGILVFLILLG
IGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR
NT seq 1254 nt   +upstreamnt  +downstreamnt
atggcccgagccatggccgccgcgtggccgctgctgctggtggcgctactggtgctgtcc
tggccacccccaggaaccggggacgtcgtcgtgcaggcgcccacccaggtgcccggcttc
ttgggcgactccgtgacgctgccctgctacctacaggtgcccaacatggaggtgacgcat
gtgtcacagctgacttgggcgcggcatggtgaatctggcagcatggccgtcttccaccaa
acgcagggccccagctattcggagtccaaacggctggaattcgtggcagccagactgggc
gcggagctgcggaatgcctcgctgaggatgttcgggttgcgcgtagaggatgaaggcaac
tacacctgcctgttcgtcacgttcccgcagggcagcaggagcgtggatatctggctccga
gtgcttgccaagccccagaacacagctgaggttcagaaggtccagctcactggagagcca
gtgcccatggcccgctgcgtctccacagggggtcgcccgccagcccaaatcacctggcac
tcagacctgggcgggatgcccaatacgagccaggtgccagggttcctgtctggcacagtc
actgtcaccagcctctggatattggtgccctcaagccaggtggacggcaagaatgtgacc
tgcaaggtggagcacgagagctttgagaagcctcagctgctgactgtgaacctcaccgtg
tactaccccccagaggtatccatctctggctatgataacaactggtaccttggccagaat
gaggccaccctgacctgcgatgctcgcagcaacccagagcccacaggctataattggagc
acgaccatgggtcccctgccaccctttgctgtggcccagggcgcccagctcctgatccgt
cctgtggacaaaccaatcaacacaactttaatctgcaacgtcaccaatgccctaggagct
cgccaggcagaactgaccgtccaggtcaaagagggacctcccagtgagcactcaggcatg
tcccgtaacgccatcatcttcctggttctgggaatcctggtttttctgatcctgctgggg
atcgggatttatttctattggtccaaatgttcccgtgaggtcctttggcactgtcatctg
tgtccctcgagtacagagcatgccagcgcctcagctaatgggcatgtctcctattcagct
gtgagcagagagaacagctcttcccaggatccacagacagagggcacaaggtga

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