Homo sapiens (human): 5834 Help Entry 5834              CDS       T01001                                  Symbol PYGB, GPBB Name (RefSeq) glycogen phosphorylase B   KO K00688   glycogen phosphorylase [EC:2.4.1.1] Organism hsa  Homo sapiens (human) Pathway hsa00500   Starch and sucrose metabolism hsa01100   Metabolic pathways hsa04217   Necroptosis hsa04910   Insulin signaling pathway hsa04922   Glucagon signaling pathway hsa04931   Insulin resistance Module hsa_M00855   Glycogen degradation, glycogen => glucose-6P Network nt06017  Glycogen metabolism   Element N00718   Glycogen degradation Drug target Ingliforib:  D04537 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00500 Starch and sucrose metabolism     5834 (PYGB)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     5834 (PYGB)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     5834 (PYGB)    04922 Glucagon signaling pathway     5834 (PYGB)  09160 Human Diseases   09167 Endocrine and metabolic disease    04931 Insulin resistance     5834 (PYGB) Enzymes [BR:hsa01000]  2. Transferases   2.4  Glycosyltransferases    2.4.1  Hexosyltransferases     2.4.1.1  glycogen phosphorylase      5834 (PYGB) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Phosphorylase TPR_22 Motif Other DBs NCBI-GeneID:  5834 NCBI-ProteinID:  NP_002853 OMIM:  138550 HGNC:  9723 Ensembl:  ENSG00000100994 UniProt:  P11216 Structure PDBPDBj LinkDB All DBs Position 20:25248085..25298012 Genome browser AA seq 843 aa AA seqDB search MAKPLTDSEKRKQISVRGLAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTV RDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDL EELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEA DDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVN TMRLWSAKAPNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFV VAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKV DWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFP GDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKF QNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQ ENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFV PRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPA ADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVE ALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIVNMLMHHDRFKVFADYEA YMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNI PRD NT seq 2532 nt NT seq  +upstreamnt  +downstreamnt atggcgaagccgctgacggacagcgagaagcggaagcagatcagcgtgcgcggcctggcg gggctaggcgacgtggccgaggtgcggaagagcttcaaccggcacttgcacttcacgctg gtcaaggaccgcaatgtggccacgccccgcgactacttcttcgcgctggcgcacacggtg cgcgaccacctcgtgggccgctggatccgcacgcagcagcactactacgagcgcgacccc aagcgcatttattatctttccctggaattctacatgggtcgcacgctgcagaacacgatg gtgaacctgggccttcagaatgcctgcgatgaagccatctatcagttggggttagacttg gaggaactcgaggagatagaagaagatgctggccttgggaatggaggcctggggaggctg gcagcgtgtttccttgactcaatggctaccttgggcctggcagcatacggctatggaatc cgctatgaatttgggatttttaaccagaagattgtcaatggctggcaggtagaggaggcc gatgactggctgcgctacggcaacccctgggagaaagcgcggcctgagtatatgcttccc gtgcacttctacggacgcgtggagcacacccccgacggcgtgaagtggctggacacacag gtggtgctggccatgccctacgacaccccagtgcccggctacaagaacaacaccgtcaac accatgcggctgtggtccgccaaggctcccaacgacttcaagctgcaggacttcaacgtg ggagactacatcgaggcggtcctggaccggaacttggctgagaacatctccagggtcctg tatccaaatgataacttctttgaggggaaggagctgcggctgaagcaggagtacttcgtg gtggccgccacgctccaggacatcatccgccgcttcaagtcgtccaagttcggctgccgg gaccctgtgagaacctgtttcgagacgttcccagacaaggtggccatccagctgaacgac acccaccccgccctctccatccctgagctcatgcggatcctggtggacgtggagaaggtg gactgggacaaggcctgggaaatcacgaagaagacctgtgcatacaccaaccacactgtg ctgcctgaggccttggagcgctggcccgtgtccatgtttgagaagctgctgccgcggcac ctggagataatctatgccatcaaccagcggcacctggaccacgtggccgcgctgtttccc ggcgatgtggaccgcctgcgcaggatgtctgtgatcgaggagggggactgcaagcggatc aacatggcccacctgtgtgtgattgggtcccatgctgtcaatggtgtggcgaggatccac tcggagatcgtgaaacagtcggtctttaaggatttttatgaactggagccagagaagttc cagaataagaccaatggcatcaccccccgccggtggctgctgctgtgcaacccggggctg gccgataccatcgtggagaaaattggggaggagttcctgactgacctgagccagctgaag aagctgctgccgctggtcagtgacgaggtgttcatcagggacgtggccaaggtcaaacag gagaacaagctcaagttctcggccttcctggagaaggagtacaaggtgaagatcaacccc tcctccatgttcgatgtgcatgtgaagaggatccacgagtacaagcggcagctgctcaac tgcctgcacgtcgtcaccctgtacaatcgaatcaagagagacccggccaaggcttttgtg cccaggactgttatgattgggggcaaggcagcgcccggttaccacatggccaagctgatc atcaagttggtcacctccatcggcgacgtcgtcaatcatgacccagttgtgggtgacagg ttgaaagtgatcttcctggagaactaccgtgtgtccttggctgagaaagtgatcccggcc gctgatctgtcgcagcagatctccactgcaggcaccgaggcctcaggcacaggcaacatg aagttcatgctcaacggggccctcaccatcggcaccatggacggcgccaacgtggagatg gccgaggaggccggggccgagaacctcttcatcttcggcctgcgggtggaggatgtcgag gccttggaccggaaagggtacaatgccagggagtactacgaccacctgcccgagctgaag caggccgtggaccagatcagcagtggctttttttctcccaaggagccagactgcttcaag gacatcgtgaacatgctgatgcaccatgacaggttcaaggtgtttgcagactatgaagcc tacatgcagtgccaggcacaggtggaccagctgtaccggaaccccaaggagtggaccaag aaggtcatcaggaacatcgcctgctcgggcaagttctccagtgaccggaccatcacggag tatgcacgggagatctggggtgtggagccctccgacctgcagatcccgccccccaacatc ccccgggactag

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