Homo sapiens (human): 58508 Help Entry 58508             CDS       T01001                                  Symbol KMT2C, HALR, KLEFS2, MLL3 Name (RefSeq) lysine methyltransferase 2C   KO K09188   [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354] Organism hsa  Homo sapiens (human) Pathway hsa00310   Lysine degradation hsa01100   Metabolic pathways Disease H00907   Kleefstra syndrome H02434   Diffuse large B-cell lymphoma, not otherwise specified Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09105 Amino acid metabolism    00310 Lysine degradation     58508 (KMT2C)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:hsa03036]     58508 (KMT2C) Enzymes [BR:hsa01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.1  Methyltransferases     2.1.1.354  [histone H3]-lysine4 N-trimethyltransferase      58508 (KMT2C) Chromosome and associated proteins [BR:hsa03036]  Eukaryotic type   Histone modification proteins    HMTs (histone methyltransferases)     HKMTs (histone lysine methyltransferases)      58508 (KMT2C)    HMT complexes     MLL3/MLL4 complex      58508 (KMT2C) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PHD SET FYRC FYRN zf-HC5HC2H_2 zf-HC5HC2H PHDvar_NSD HMG_box Motif Other DBs NCBI-GeneID:  58508 NCBI-ProteinID:  NP_733751 OMIM:  606833 HGNC:  13726 Ensembl:  ENSG00000055609 UniProt:  Q8NEZ4 Structure PDBPDBj LinkDB All DBs Position 7:complement(152134925..152436003) Genome browser AA seq 4911 aa AA seqDB search MSSEEDKSVEQPQPPPPPPEEPGAPAPSPAAADKRPRGRPRKDGASPFQRARKKPRSRGK TAVEDEDSMDGLETTETETIVETEIKEQSAEEDAEAEVDNSKQLIPTLQRSVSEESANSL VSVGVEAKISEQLCAFCYCGEKSSLGQGDLKQFRITPGFILPWRNQPSNKKDIDDNSNGT YEKMQNSAPRKQRGQRKERSPQQNIVSCVSVSTQTASDDQAGKLWDELSLVGLPDAIDIQ ALFDSTGTCWAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCCEE KCTQMYHYPCAAGAGTFQDFSHIFLLCPEHIDQAPERSKEDANCAVCDSPGDLLDQFFCT TCGQHYHGMCLDIAVTPLKRAGWQCPECKVCQNCKQSGEDSKMLVCDTCDKGYHTFCLQP VMKSVPTNGWKCKNCRICIECGTRSSSQWHHNCLICDNCYQQQDNLCPFCGKCYHPELQK DMLHCNMCKRWVHLECDKPTDHELDTQLKEEYICMYCKHLGAEMDRLQPGEEVEIAELTT DYNNEMEVEGPEDQMVFSEQAANKDVNGQESTPGIVPDAVQVHTEEQQKSHPSESLDTDS LLIAVSSQHTVNTELEKQISNEVDSEDLKMSSEVKHICGEDQIEDKMEVTENIEVVTHQI TVQQEQLQLLEEPETVVSREESRPPKLVMESVTLPLETLVSPHEESISLCPEEQLVIERL QGEKEQKENSELSTGLMDSEMTPTIEGCVKDVSYQGGKSIKLSSETESSFSSSADISKAD VSSSPTPSSDLPSHDMLHNYPSALSSSAGNIMPTTYISVTPKIGMGKPAITKRKFSPGRP RSKQGAWSTHNTVSPPSWSPDISEGREIFKPRQLPGSAIWSIKVGRGSGFPGKRRPRGAG LSGRGGRGRSKLKSGIGAVVLPGVSTADISSNKDDEENSMHNTVVLFSSSDKFTLNQDMC VVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKITKVVLSKGWRCLECTVCEACGKATDPG RLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGLRCEWQNNYTQCAP CASLSSCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYM PASNVPSSDCCESSLVAQIVTKVKELDPPKTYTQDGVCLTESGMTQLQSLTVTVPRRKRS KPKLKLKIINQNSVAVLQTPPDIQSEHSRDGEMDDSREGELMDCDGKSESSPEREAVDDE TKGVEGTDGVKKRKRKPYRPGIGGFMVRQRSRTGQGKTKRSVIRKDSSGSISEQLPCRDD GWSEQLPDTLVDESVSVTESTEKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQSK ISLDNLSEDGAQLLYKTNMNTGFLDPSLDPLLSSSSAPTKSGTHGPADDPLADISEVLNT DDDILGIISDDLAKSVDHSDIGPVTDDPSSLPQPNVNQSSRPLSEEQLDGILSPELDKMV TDGAILGKLYKIPELGGKDVEDLFTAVLSPANTQPTPLPQPPPPTQLLPIHNQDAFSRMP LMNGLIGSSPHLPHNSLPPGSGLGTFSAIAQSSYPDARDKNSAFNPMASDPNNSWTSSAP TVEGENDTMSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFPDWTTRVKQIAK LWRKASSQERAPYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSELFKDPL KQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSD TPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPS RIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSA APVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPK SLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGP GPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLT PHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYS QPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQ PPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPG PGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNS PMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKI AGRQEKGSQDSPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPK DQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVSV DMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGS VVEASSNLRHGNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVH SSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQPSDGLEEKLDSDDPSVKELD VKDLEGVEVKDLDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEFDIIAYT DPELDMGDKKSMFNEELDLPIDDKLDNQCVSVEPKKKEQENKTLVLSDKHSPQKKSTVTN EVKTEVLSPNSKVESKCETEKNDENKDNVDTPCSQASAHSDLNDGEKTSLHPCDPDLFEK RTNRETAGPSANVIQASTQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPP PTLPASPSNHVSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTV NHSLGTGKPATQTGPQTSQSGTSSMSGPQQLMIPQTLAQQNRERPLLLEEQPLLLQDLLD QERQEQQQQRQMQAMIRQRSEPFFPNIDFDAITDPIMKAKMVALKGINKVMAQNNLGMPP MVMSRFPFMGQVVTGTQNSEGQNLGPQAIPQDGSITHQISRPNPPNFGPGFVNDSQRKQY EEWLQETQQLLQMQQKYLEEQIGAHRKSKKALSAKQRTAKKAGREFPEEDAEQLKHVTEQ QSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMS QPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPI KTCTPAPGTVSNANPQSGPPPRVEFDDNNPFSESFQERERKERLREQQERQRIQLMQEVD RQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMG QVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLS GTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHGHSYPGSTQSLIQLYSDIIPEE KGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSELPQQADQES VEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKL EKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHL LKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPKT DGGSETKKQRSKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTP PASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLAR ALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPD LSLVKEEPPEPVPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLI SVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHRINPGLEYRQ HLLLRGPPPGSANPPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIAESAALRPQWCCH CKVVILGSGVRKSFKDLTLLNKDSRESTKRVEKDIVFCSNNCFILYSSTAQAKNSENKES IPSLPQSPMRETPSKAFHQYSNNISTLDVHCLPQLPEKASPPASPPIAFPPAFEAAQVEA KPDELKVTVKLKPRLRAVHGGFEDCRPLNKKWRGMKWKKWSIHIVIPKGTFKPPCEDEID EFLKKLGTSLKPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVY ETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDKT MLCPMHKPKGIHEQELSYFAVFRRVYVQRDEVRQIASIVQRGERDHTFRVGSLIFHTIGQ LLPQQMQAFHSPKALFPVGYEASRLYWSTRYANRRCRYLCSIEEKDGRPVFVIRIVEQGH EDLVLSDISPKGVWDKILEPVACVRKKSEMLQLFPAYLKGEDLFGLTVSAVARIAESLPG VEACENYTFRYGRNPLMELPLAVNPTGCARSEPKMSAHVKRFVLRPHTLNSTSTSKSFQS TVTGELNAPYSKQFVHSKSSQYRKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEY IGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVV TFERGHKIIISSSRRIQKGEELCYDYKFDFEDDQHKIPCHCGAVNCRKWMN NT seq 14736 nt NT seq  +upstreamnt  +downstreamnt atgtcgtcggaggaggacaagagcgtggagcagccgcagccgccgccaccaccccccgag gagcctggagccccggccccgagccccgcagccgcagacaaaagacctcggggccggcct cgcaaagatggcgcttcccctttccagagagccagaaagaaacctcgaagtagggggaaa actgcagtggaagatgaggacagcatggatgggctggagacaacagaaacagaaacgatt gtggaaacagaaatcaaagaacaatctgcagaagaggatgctgaagcagaagtggataac agcaaacagctaattccaactcttcagcgatctgtgtctgaggaatcggcaaactccctg gtctctgttggtgtagaagccaaaatcagtgaacagctctgcgctttttgttactgtggg gaaaaaagttccttaggacaaggagacttaaaacaattcagaataacgcctggatttatc ttgccatggagaaaccaaccttctaacaagaaggacattgatgacaacagcaatggaacc tatgagaaaatgcaaaactcagcaccacgaaaacaaagaggacagagaaaagaacgatct cctcagcagaatatagtatcttgtgtaagtgtaagcacccagacagcttcagatgatcaa gctggtaaactgtgggatgaactcagtctggttgggcttccagatgccattgatatccaa gccttatttgattctacaggcacttgttgggctcatcaccgttgtgtggagtggtcacta ggagtatgccagatggaagaaccattgttagtgaacgtggacaaagctgttgtctcaggg agcacagaacgatgtgcattttgtaagcaccttggagccactatcaaatgctgtgaagag aaatgtacccagatgtatcattatccttgtgctgcaggagccggcacctttcaggatttc agtcacatcttcctgctttgtccagaacacattgaccaagctcctgaaagatcgaaggaa gatgcaaactgtgcagtgtgcgacagcccgggagacctcttagatcagttcttttgtact acttgtggtcagcactatcatggaatgtgcctggatatagcggttactccattaaaacgt gcaggttggcaatgtcctgagtgcaaagtgtgccagaactgcaaacaatcgggagaagat agcaagatgctagtgtgtgatacgtgtgacaaagggtatcatactttttgtcttcaacca gttatgaaatcagtaccaaccaatggctggaaatgcaaaaattgcagaatatgtatagag tgtggcacacggtctagttctcagtggcaccacaattgcctgatatgtgacaattgttac caacagcaggataacttatgtcccttctgtgggaagtgttatcatccagaattgcagaaa gacatgcttcattgtaatatgtgcaaaaggtgggttcacctagagtgtgacaaaccaaca gatcatgaactggatactcagctcaaagaagagtatatctgcatgtattgtaaacacctg ggagctgagatggatcgtttacagccaggtgaggaagtggagatagctgagctcactaca gattataacaatgaaatggaagttgaaggccctgaagatcaaatggtattctcagagcag gcagctaataaagatgtcaacggtcaggagtccactcctggaattgttccagatgcggtt caagtccacactgaagagcaacagaagagtcatccctcagaaagtcttgacacagatagt cttcttattgctgtatcatcccaacatacagtgaatactgaattggaaaaacagatttct aatgaagttgatagtgaagacctgaaaatgtcttctgaagtgaagcatatttgtggcgaa gatcaaattgaagataaaatggaagtgacagaaaacattgaagtcgttacacaccagatc actgtgcagcaagaacaactgcagttgttagaggaacctgaaacagtggtatccagagaa gaatcaaggcctccaaaattagtcatggaatctgtcactcttccactagaaaccttagtg tccccacatgaggaaagtatttcattatgtcctgaggaacagttggttatagaaaggcta caaggagaaaaggaacagaaagaaaattctgaactttctactggattgatggactctgaa atgactcctacaattgagggttgtgtgaaagatgtttcataccaaggaggcaaatctata aagttatcatctgagacagagtcatcattttcatcatcagcagacataagcaaggcagat gtgtcttcctccccaacaccttcttcagacttgccttcgcatgacatgctgcataattac ccttcagctcttagttcctctgctggaaacatcatgccaacaacttacatctcagtcact ccaaaaattggcatgggtaaaccagctattactaagagaaaattttctcctggtagacct cggtccaaacagggggcttggagtacccataatacagtgagcccaccttcctggtcccca gacatttcagaaggtcgggaaatttttaaacccaggcagcttcctggcagtgccatttgg agcatcaaagtgggccgtgggtctggatttccaggaaagcggagacctcgaggtgcagga ctgtcggggcgaggtggccgaggcaggtcaaagctgaaaagtggaatcggagctgttgta ttacctggggtgtctactgcagatatttcatcaaataaggatgatgaagaaaactctatg cacaatacagttgtgttgttttctagcagtgacaagttcactttgaatcaggatatgtgt gtagtttgtggcagttttggccaaggagcagaaggaagattacttgcctgttctcagtgt ggtcagtgttaccatccatactgtgtcagtattaagatcactaaagtggttcttagcaaa ggttggaggtgtcttgagtgcactgtgtgtgaggcctgtgggaaggcaactgacccagga agactcctgctgtgtgatgactgtgacataagttatcacacctactgcctagaccctcca ttgcagacagttcccaaaggaggctggaagtgcaaatggtgtgtttggtgcagacactgt ggagcaacatctgcaggtctaagatgtgaatggcagaacaattacacacagtgcgctcct tgtgcaagcttatcttcctgtccagtctgctatcgaaactatagagaagaagatcttatt ctgcaatgtagacaatgtgatagatggatgcatgcagtttgtcagaacttaaatactgag gaagaagtggaaaatgtagcagacattggttttgattgtagcatgtgcagaccctatatg cctgcgtctaatgtgccttcctcagactgctgtgaatcttcacttgtagcacaaattgtc acaaaagtaaaagagctagacccacccaagacttatacccaggatggtgtgtgtttgact gaatcagggatgactcagttacagagcctcacagttacagttccaagaagaaaacggtca aaaccaaaattgaaattgaagattataaatcagaatagcgtggccgtccttcagacccct ccagacatccaatcagagcattcaagggatggtgaaatggatgatagtcgagaaggagaa cttatggattgtgatggaaaatcagaatctagtcctgagcgggaagctgtggatgatgaa actaagggagtggaaggaacagatggtgtcaaaaagagaaaaaggaaaccatacagacca ggtattggtggatttatggtgcggcaaagaagtcgaactgggcaagggaaaaccaaaaga tctgtgatcagaaaagattcctcaggctctatttccgagcagttaccttgcagagatgat ggctggagtgagcagttaccagatactttagttgatgaatctgtttctgttactgaaagc actgaaaaaataaagaagagataccgaaaaaggaaaaataagcttgaagaaactttccct gcctatttacaagaagctttctttggaaaagatcttctagatacaagtagacaaagcaag ataagtttagataatctgtcagaagatggagctcagcttttatataaaacaaacatgaac acaggtttcttggatccttccttagatccactacttagttcatcctcggctccaacaaaa tctggaactcacggtcctgctgatgacccattagctgatatttctgaagttttaaacaca gatgatgacattcttggaataatttcagatgatctagcaaaatcagttgatcattcagat attggtcctgtcactgatgatccttcctctttgcctcagccaaatgtcaatcagagttca cgaccattaagtgaagaacagctagatgggatcctcagtcctgaactagacaaaatggtc acagatggagcaattcttggaaaattatataaaattccagagcttggcggaaaagatgtt gaagacttatttacagctgtacttagtcctgcgaacactcagccaactccattgccacag cctcccccaccaacacagctgttgccaatacacaatcaggatgctttttcacggatgcct ctcatgaatggccttattggatccagtcctcatctcccacataattctttgccacctgga agcggactgggaactttctctgcaattgcacaatcctcttatcctgatgccagggataaa aattcagcctttaatccaatggcaagtgatcctaacaactcttggacatcatcagctccc actgtggaaggagaaaatgacacaatgtcgaatgcccagagaagcacgcttaagtgggag aaagaggaggctctgggtgaaatggcaactgttgccccagttctctacaccaatattaat ttccccaacttaaaggaagaattccctgattggactactagagtgaagcaaattgccaaa ttgtggagaaaagcaagctcacaagaaagagcaccatatgtgcaaaaagccagagataac agagctgctttacgcattaataaagtacagatgtcaaatgattccatgaaaaggcagcaa cagcaagatagcattgatcccagctctcgtattgattcggagctttttaaagatccttta aagcaaagagaatcagaacatgaacaggaatggaaatttagacagcaaatgcgtcagaaa agtaagcagcaagctaaaattgaagccacacagaaacttgaacaggtgaaaaatgagcag cagcagcagcaacaacagcaatttggttctcagcatcttctggtgcagtctggttcagat acaccaagtagtgggatacagagtcccttgacacctcagcctggcaatggaaatatgtct cctgcacagtcattccataaagaactgtttacaaaacagccacccagtacccctacgtct acatcttcagatgatgtgtttgtaaagccacaagctccacctcctcctccagccccatcc cggattcccatccaggatagtctttctcaggctcagacttctcagccaccctcaccgcaa gtgttttcacctgggtcctctaactcacgaccaccatctccaatggatccatatgcaaaa atggttggtacccctcgaccacctcctgtgggccatagtttttccagaagaaattctgct gcaccagtggaaaactgtacacctttatcatcggtatctaggccccttcaaatgaatgag acaacagcaaataggccatcccctgtcagagatttatgttcttcttccacgacaaataat gacccctatgcaaaacctccagacacacctaggcctgtgatgacagatcaatttcccaaa tccttgggcctatcccggtctcctgtagtttcagaacaaactgcaaaaggccctatagca gctggaaccagtgatcactttactaaaccatctcctagggcagatgtgtttcaaagacaa aggatacctgactcatatgcacgacccttgttgacacctgcacctcttgatagtggtcct ggaccttttaagactccaatgcaacctcctccatcctctcaggatccttatggatcagtg tcacaggcatcaaggcgattgtctgttgacccttatgaaaggcctgctttgacaccaaga cctatagataatttttctcataatcagtcaaatgatccatatagtcagcctccccttacc ccacatccagcagtgaatgaatcttttgcccatccttcaagggctttttcccagcctgga accatatcaaggccaacatctcaggacccatactcccaacccccaggaactccacgacct gttgtagattcttattcccaatcttcaggaacagctaggtccaatacagacccttactct caacctcctggaactccccggcctactactgttgacccatatagtcagcagccccaaacc ccaagaccatctacacaaactgacttgtttgttacacctgtaacaaatcagaggcattct gatccatatgctcatcctcctggaacaccaagacctggaatttctgtcccttactctcag ccaccagcaacaccaaggccaaggatttcagagggttttactaggtcctcaatgacaaga ccagtcctcatgccaaatcaggatcctttcctgcaagcagcacaaaaccgaggaccagct ttacctggcccgttggtaaggccacctgatacatgttcccagacacctaggccccctgga cctggtctttcagacacatttagccgtgtttccccatctgctgcccgtgatccctatgat cagtctccaatgactccaagatctcagtctgactcttttggaacaagtcaaactgcccat gatgttgctgatcagccaaggcctggatcagaggggagcttctgtgcatcttcaaactct ccaatgcactcccaaggccagcagttctctggtgtctcccaacttcctggacctgtgcca acttcaggagtaactgatacacagaatactgtaaatatggcccaagcagatacagagaaa ttgagacagcggcagaagttacgtgaaatcattctccagcagcaacagcagaagaagatt gcaggtcgacaggagaaggggtcacaggactcacccgcagtgcctcatccagggcctctt caacactggcaaccagagaatgttaaccaggctttcaccagacccccacctccctatcct gggaacattaggtctcctgttgcccctcctttaggacctagatatgctgttttcccaaaa gatcagcgtggaccctatcctcctgatgttgctagtatggggatgagacctcatggattt agatttggatttccaggaggtagtcatggtaccatgccgagtcaagagcgcttccttgtg cctcctcagcaaatacagggatctggagtttctccacagctaagaagatcagtatctgta gatatgcctaggcctttaaataactcacaaatgaataatccagttggacttcctcagcat ttttcaccacagagcttgccagttcagcagcacaacatactgggccaagcatatattgaa ctgagacatagggctcctgacggaaggcaacggctgcctttcagtgctccacctggcagc gttgtagaggcatcttctaatctgagacatggaaacttcattccccggccagactttccg ggccctagacacacagaccccatgcgacgacctccccagggtctacctaatcagctacct gtgcacccagatttggaacaagtgccaccatctcaacaagagcaaggtcattctgtccat tcatcttctatggtcatgaggactctgaaccatccactaggtggtgaattttcagaagct cctttgtcaacatctgtaccgtctgaaacaacgtctgataatttacagataaccacccag ccttctgatggtctagaggaaaaacttgattctgatgacccttctgtgaaggaactggat gttaaagaccttgagggggttgaagtcaaagacttagatgatgaagatcttgaaaactta aatttagatacagaggatggcaaggtagttgaattggatactttagataatttggaaact aatgatcccaacctggatgacctcttaaggtcaggagagtttgatatcattgcatataca gatccagaacttgacatgggagataagaaaagcatgtttaatgaggaactagaccttcca attgatgataagttagataatcagtgtgtatctgttgaaccaaaaaaaaaggaacaagaa aacaaaactctggttctctctgataaacattcaccacagaaaaaatccactgttaccaat gaggtaaaaacggaagtactgtctccaaattctaaggtggaatccaaatgtgaaactgaa aaaaatgatgagaataaagataatgttgacactccttgctcacaggcttctgctcactca gacctaaatgatggagaaaagacttctttgcatccttgtgatccagatctatttgagaaa agaaccaatcgagaaactgctggccccagtgcaaatgtcattcaggcatccactcaacta cctgctcaagatgtaataaactcttgtggcataactggatcaactccagttctctcaagt ttacttgctaatgagaaatctgataattcagacattaggccatcggggtctccaccacca ccaactctgccggcctccccatccaatcatgtgtcaagtttgcctcctttcatagcaccg cctggccgtgttttggataatgccatgaattctaatgtgacagtagtctctagggtaaac catgttttttctcagggtgtgcaggtaaacccagggctcattccaggtcaatcaacagtt aaccacagtctggggacaggaaaacctgcaactcaaactgggcctcaaacaagtcagtct ggtaccagtagcatgtctggaccccaacagctaatgattcctcaaacattagcacagcag aatagagagaggccccttcttctagaagaacagcctctacttctacaggatcttttggat caagaaaggcaagaacagcagcagcaaagacagatgcaagccatgattcgtcagcgatca gaaccgttcttccctaatattgattttgatgcaattacagatcctataatgaaagccaaa atggtggcccttaaaggtataaataaagtgatggcacaaaacaatctgggcatgccacca atggtgatgagcaggttcccttttatgggccaggtggtaactggaacacagaacagtgaa ggacagaaccttggaccacaggccattcctcaggatggcagtataacacatcagatttct aggcctaatcctccaaattttggtccaggctttgtcaatgattcacagcgtaagcagtat gaagagtggctccaggagacccaacagctgcttcaaatgcagcagaagtatcttgaagaa caaattggtgctcacagaaaatctaagaaggccctttcagctaaacaacgtactgccaag aaagctgggcgtgaatttccagaggaagatgcagaacaactcaagcatgttactgaacag caaagcatggttcagaaacagctagaacagattcgtaaacaacagaaagaacatgctgaa ttgattgaagattatcggatcaaacagcagcagcaatgtgcaatggccccacctaccatg atgcccagtgtccagccccagccacccctaattccaggtgccactccacccaccatgagc caacccacctttcccatggtgccacagcagcttcagcaccagcagcacacaacagttatt tctggccatactagccctgttagaatgcccagtttacctggatggcaacccaacagtgct cctgcccacctgcccctcaatcctcctagaattcagcccccaattgcccagttaccaata aaaacttgtacaccagccccagggacagtctcaaatgcaaatccacagagtggaccacca cctcgggtagaatttgatgacaacaatccctttagtgaaagttttcaagaacgggaacgt aaggaacgtttacgagaacagcaagagagacaacggatccaactcatgcaggaggtagat agacaaagagctttgcagcagaggatggaaatggagcagcatggtatggtgggctctgag ataagtagtagtaggacatctgtgtcccagattcccttctacagttccgacttaccttgt gattttatgcaacctctaggaccccttcagcagtctccacaacaccaacagcaaatgggg caggttttacagcagcagaatatacaacaaggatcaattaattcaccctccacccaaact ttcatgcagactaatgagcgaaggcaggtaggccctccttcatttgttcctgattcacca tcaatccctgttggaagcccaaatttttcttctgtgaagcagggacatggaaatctttct gggaccagcttccagcagtccccagtgaggccttcttttacacctgctttaccagcagca cctccagtagctaatagcagtctcccatgtggccaagattctactataacccatggacac agttatccgggatcaacccaatcgctcattcagttgtattctgatataatcccagaggaa aaagggaaaaagaaaagaacaagaaagaagaaaagagatgatgatgcagaatccaccaag gctccatcaactccccattcagatataactgccccaccgactccaggcatctcagaaact acctctactcctgcagtgagcacacccagtgagcttcctcaacaagccgaccaagagtcg gtggaaccagtcggcccatccactcccaatatggcagcaggccagctatgtacagaatta gagaacaaactgcccaatagtgatttctcacaagcaactccaaatcaacagacgtatgca aattcagaagtagacaagctctccatggaaacccctgccaaaacagaagagataaaactg gaaaaggctgagacagagtcctgcccaggccaagaggagcctaaattggaggaacagaat ggtagtaaggtagaaggaaacgctgtagcctgtcctgtctcctcagcacagagtcctccc cattctgctggggcccctgctgccaaaggagactcagggaatgaacttctgaaacacttg ttgaaaaataaaaagtcatcttctcttttgaatcaaaaacctgagggcagtatttgttca gaagatgactgtacaaaggataataaactagttgagaagcagaacccagctgaaggactg caaactttgggggctcaaatgcaaggtggttttggatgtggcaaccagttgccaaaaaca gatggaggaagtgaaaccaagaaacagcgaagcaaacggactcagaggacgggtgagaaa gcagcacctcgctcaaagaaaaggaaaaaggacgaagaggagaaacaagctatgtactct agcactgacacgtttacccacttgaaacagcagaataatttaagtaatcctccaacaccc cctgcctctcttcctcctacaccacctcctatggcttgtcagaagatggccaatggtttt gcaacaactgaagaacttgctggaaaagccggagtgttagtgagccatgaagttaccaaa actctaggacctaaaccatttcagctgcccttcagaccccaggacgacttgttggcccga gctcttgctcagggccccaagacagttgatgtgccagcctccctcccaacaccacctcat aacaatcaggaagaattaaggatacaggatcactgtggtgatcgagatactcctgacagt tttgttccctcatcctctcctgagagtgtggttggggtagaagtgagcaggtatccagat ctgtcattggtcaaggaggagcctccagaaccggtgccgtcccccatcattccaattctt cctagcactgctgggaaaagttcagaatcaagaaggaatgacatcaaaactgagccaggc actttatattttgcgtcaccttttggtccttccccaaatggtcccagatcaggtcttata tctgtagcaattactctgcatcctacagctgctgagaacattagcagtgttgtggctgca ttttccgaccttcttcacgtccgaatccctaacagctatgaggttagcagtgctccagat gtcccatccatgggtttggtcagtagccacagaatcaacccgggtttggagtatcgacag catttacttctccgtgggcctccgccaggatctgcaaaccctcccagattagtgagctct taccggctgaagcagcctaatgtaccatttcctccaacaagcaatggtctttctggatat aaggattctagtcatggtattgcagaaagcgcagcactcagaccacagtggtgttgtcat tgtaaagtggttattcttggaagtggtgtgcggaaatctttcaaagatctgacccttttg aacaaggattcccgagaaagcaccaagagggtagagaaggacattgtcttctgtagtaat aactgctttattctttattcatcaactgcacaagcgaaaaactcagaaaacaaggaatcc attccttcattgccacaatcacctatgagagaaacgccttccaaagcatttcatcagtac agcaacaacatctccactttggatgtgcactgtctcccccagctcccagagaaagcttct ccccctgcctcaccacccatcgccttccctcctgcttttgaagcagcccaagtcgaggcc aagccagatgagctgaaggtgacagtcaagctgaagcctcggctaagagctgtccatggt gggtttgaagattgcaggccgctcaataaaaaatggagaggaatgaaatggaagaagtgg agcattcatattgtaatccctaaggggacatttaaaccaccttgtgaggatgaaatagat gaatttctaaagaaattgggcacttcccttaaacctgatcctgtgcccaaagactatcgg aaatgttgcttttgtcatgaagaaggtgatggattgacagatggaccagcaaggctactc aaccttgacttggatctgtgggtccacttgaactgcgctctgtggtccacggaggtctat gagactcaggctggtgccttaataaatgtggagctagctctgaggagaggcctacaaatg aaatgtgtcttctgtcacaagacgggtgccactagtggatgccacagatttcgatgcacc aacatttatcacttcacttgcgccattaaagcacaatgcatgttttttaaggacaaaact atgctttgccccatgcacaaaccaaagggaattcatgagcaagaattaagttactttgca gtcttcaggagggtctatgttcagcgtgatgaggtgcgacagattgctagcatcgtgcaa cgaggagaacgggaccatacctttcgcgtgggtagcctcatcttccacacaattggtcag ctgcttccacagcagatgcaagcattccattctcctaaagcactcttccctgtgggctat gaagccagccggctgtactggagcactcgctatgccaataggcgctgccgctacctgtgc tccattgaggagaaggatgggcgcccagtgtttgtcatcaggattgtggaacaaggccat gaagacctggttctaagtgacatctcacctaaaggtgtctgggataagattttggagcct gtggcatgtgtgagaaaaaagtctgaaatgctccagcttttcccagcgtatttaaaagga gaggatctgtttggcctgaccgtctctgcagtggcacgcatagcggaatcacttcctggg gttgaggcatgtgaaaattataccttccgatacggccgaaatcctctcatggaacttcct cttgccgttaaccccacaggttgtgcccgttctgaacctaaaatgagtgcccatgtcaag aggtttgtgttaaggcctcacaccttaaacagcaccagcacctcaaagtcatttcagagc acagtcactggagaactgaacgcaccttatagtaaacagtttgttcactccaagtcatcg cagtaccggaagatgaaaactgaatggaaatccaatgtgtatctggcacggtctcggatt caggggctgggcctgtatgctgctcgagacattgagaaacacaccatggtcattgagtac atcgggactatcattcgaaacgaagtagccaacaggaaagagaagctttatgagtctcag aaccgtggtgtgtacatgttccgcatggataacgaccatgtgattgacgcgacgctcaca ggagggcccgcaaggtatatcaaccattcgtgtgcacctaattgtgtggctgaagtggtg acttttgagagaggacacaaaattatcatcagctccagtcggagaatccagaaaggagaa gagctctgctatgactataagtttgactttgaagatgaccagcacaagattccgtgtcac tgtggagctgtgaactgccggaagtggatgaactga

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