Homo sapiens (human): 5871
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Entry
5871 CDS
T01001
Symbol
MAP4K2, BL44, GCK, RAB8IP
Name
(RefSeq) mitogen-activated protein kinase kinase kinase kinase 2
KO
K04414
mitogen-activated protein kinase kinase kinase kinase 2 [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04010
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
5871 (MAP4K2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
5871 (MAP4K2)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: STE group
STE20 family
5871 (MAP4K2)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
CNH
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
Motif
Other DBs
NCBI-GeneID:
5871
NCBI-ProteinID:
NP_004570
OMIM:
603166
HGNC:
6864
Ensembl:
ENSG00000168067
UniProt:
Q12851
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All DBs
Position
11:complement(64784918..64803214)
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AA seq
820 aa
AA seq
DB search
MALLRDVSLQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQQ
EITILRECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREA
LKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAP
EVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKT
RWTQNFHHFLKLALTKNPKKRPTAEKLLQHPFTTQQLPRALLTQLLDKASDPHLGTPSPE
DCELETYDMFPDTIHSRGQHGPAERTPSEIQFHQVKFGAPRRKETDPLNEPWEEEWTLLG
KEELSGSLLQSVQEALEERSLTIRSASEFQELDSPDDTMGTIKRAPFLGPLPTDPPAEEP
LSSPPGTLPPPPSGPNSSPLLPTAWATMKQREDPERSSCHGLPPTPKVHMGACFSKVFNG
CPLRIHAAVTWIHPVTRDQFLVVGAEEGIYTLNLHELHEDTLEKLISHRCSWLYCVNNVL
LSLSGKSTHIWAHDLPGLFEQRRLQQQVPLSIPTNRLTQRIIPRRFALSTKIPDTKGCLQ
CRVVRNPYTGATFLLAALPTSLLLLQWYEPLQKFLLLKNFSSPLPSPAGMLEPLVLDGKE
LPQVCVGAEGPEGPGCRVLFHVLPLEAGLTPDILIPPEGIPGSAQQVIQVDRDTILVSFE
RCVRIVNMQGEPTATLAPELTFDFPIETVVCLQDSVLAFWSHGMQGRSLDTNEVTQEITD
ETRIFRVLGAHRDIILESIPTDNPEAHSNLYILTGHQSTY
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atggcgctgctgcgggatgtgtcgctgcaggacccgcgggaccgcttcgagctgctgcag
cgcgtgggggccgggacctatggcgacgtctacaaggcccgcgacacggtcacgtccgaa
ctggccgccgtgaagatagtcaagctagacccaggggacgacatcagctccctccagcag
gaaatcaccatcctgcgtgagtgccgccaccccaatgtggtggcctacattggcagctac
ctcaggaatgaccgcttgtggatctgcatggagttctgcggagggggctccctgcaggag
atttaccatgccactgggcccctggaggagcggcagattgcctacgtctgccgagaggca
ctgaaggggctccaccacctgcattctcaggggaagatccacagagacatcaagggagcc
aaccttctcctcactctccagggagatgtcaaactggctgactttggggtgtcaggcgag
ctgacagcgtctgtggccaagaggaggtctttcattgggactccctactggatggctccc
gaggtggctgctgtggagcgcaaaggtggctacaatgagctatgtgacgtctgggccctg
ggcatcactgccattgagctgggcgagctgcagccccctctgttccacctgcaccccatg
agggccctgatgctcatgtcgaagagcagcttccagccgcccaaactgagagataagact
cgctggacccagaatttccaccactttctcaaactggccctgaccaagaatcctaagaag
aggccgacagcagagaagctcctgcagcacccgttcacgactcagcagctccctcgggcc
ctcctcacacagctgctggacaaagccagtgaccctcatctggggaccccctcccctgag
gactgtgagctggagacctatgacatgtttccagacaccattcactcccgggggcagcac
ggcccagccgagaggaccccctcggagatccagtttcaccaggtgaaatttggcgcccca
cgcaggaaggaaactgacccactgaatgagccgtgggaggaagagtggacactactggga
aaggaagagttgagtgggagcctgctgcagtcggtccaggaggccctggaggaaaggagt
ctgactattcggtcagcctcagaattccaggagctggactccccagacgataccatggga
accatcaagcgggccccgttcctagggccactccccactgaccctccagcagaggagcct
ctgtccagtcccccaggaaccctgcccccacctccttcaggccccaacagctccccactg
ctgcccacggcctgggccaccatgaagcagcgggaggatcctgagaggtcatcctgccac
gggctccccccaactcccaaggtgcatatgggcgcctgcttctccaaggtcttcaatggc
tgccccctgcggatccacgctgctgtcacctggattcaccctgttactcgggaccagttc
ctggtggtaggggccgaggaaggcatctacacactcaacctgcatgaactgcatgaggat
acgctggagaagctgatttcacatcgctgctcctggctctactgcgtgaacaacgtgctg
ctgtcactctcagggaaatccacgcacatctgggcccatgacctcccaggcctgtttgag
cagcggaggctacagcaacaggttcccctctccatccccaccaaccgcctcacccagcgc
atcatccccaggcgctttgctctgtccaccaagattcctgacaccaaaggctgcttgcag
tgtcgtgtggtgcggaacccctacacgggtgccaccttcctgctggccgccctgcccacc
agcctgctcctgctgcagtggtatgagccgctgcagaagtttctgctgctgaagaacttc
tccagccctctgcccagcccagctgggatgctggagccgctggtgctggatgggaaggag
ctgccgcaggtgtgtgttggggccgaggggcctgaggggcccggctgccgcgtcctgttc
catgtcctgcccctggaggctggcctgacgcccgacatcctcatcccacctgaggggatc
ccaggctcggcccagcaggtgatccaggtggacagggacacaatcctagtcagctttgaa
cgctgtgtgaggattgtcaacatgcagggcgagcccacggccacactggcacctgagctg
acctttgatttccccatcgagactgtggtgtgcctgcaggacagtgtgctggccttctgg
agccatgggatgcaaggccgaagcctggataccaatgaggtgacccaggagatcacagat
gaaacaaggatcttccgagtgcttggggcccacagagacatcatcctggagagcattccc
actgacaacccagaggcgcacagcaacctctacatcctcacgggccaccagagcacctac
taa
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