Homo sapiens (human): 5884 Help Entry 5884              CDS       T01001                                  Symbol RAD17, CCYC, HRAD17, R24L, RAD17SP, RAD24 Name (RefSeq) RAD17 checkpoint clamp loader component   KO K06662   cell cycle checkpoint protein Organism hsa  Homo sapiens (human) Network nt06506  Double-strand break repair   Element N01451   ATR signaling Brite KEGG Orthology (KO) [BR:hsa00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03400 DNA repair and recombination proteins [BR:hsa03400]     5884 (RAD17) DNA repair and recombination proteins [BR:hsa03400]  Eukaryotic type   Check point factors    HRAD17(Rad24)-RFC complex     5884 (RAD17) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Rad17 AAA_18 AAA AAA_16 RuvB_N AAA_22 AAA_28 ABC_tran nSTAND3 AAA_17 T2SSE AAA_assoc_2 Viral_helicase1 NPHP3_N AAA_19 AAA_11 ATPase_2 AAA_30 ORC-CDC6-like AAA_14 RNA_helicase dNK NTPase_1 DMA AAA_5 AAA_33 Motif Other DBs NCBI-GeneID:  5884 NCBI-ProteinID:  NP_579917 OMIM:  603139 HGNC:  9807 Ensembl:  ENSG00000152942 UniProt:  O75943 Structure PDBPDBj LinkDB All DBs Position 5:69369293..69414801 Genome browser AA seq 681 aa AA seqDB search MSKTFLRPKVSSTKVTDWVDPSFDDFLECSGVSTITATSLGVNNSSHRRKNGPSTLESSR FPARKRGNLSSLEQIYGLENSKEYLSENEPWVDKYKPETQHELAVHKKKIEEVETWLKAQ VLERQPKQGGSILLITGPPGCGKTTTLKILSKEHGIQVQEWINPVLPDFQKDDFKGMFNT ESSFHMFPYQSQIAVFKEFLLRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLH EVLRKYVRIGRCPLIFIISDSLSGDNNQRLLFPKEIQEECSISNISFNPVAPTIMMKFLN RIVTIEANKNGGKITVPDKTSLELLCQGCSGDIRSAINSLQFSSSKGENNLRPRKKGMSL KSDAVLSKSKRRKKPDRVFENQEVQAIGGKDVSLFLFRALGKILYCKRASLTELDSPRLP SHLSEYERDTLLVEPEEVVEMSHMPGDLFNLYLHQNYIDFFMEIDDIVRASEFLSFADIL SGDWNTRSLLREYSTSIATRGVMHSNKARGYAHCQGGGSSFRPLHKPQWFLINKKYRENC LAAKALFPDFCLPALCLQTQLLPYLALLTIPMRNQAQISFIQDIGRLPLKRHFGRLKMEA LTDREHGMIDPDSGDEAQLNGGHSAEESLGEPTQATVPETWSLPLSQNSASELPASQPQP FSAQGDMEENIIIEDYESDGT NT seq 2046 nt NT seq  +upstreamnt  +downstreamnt atgtcaaaaacttttcttagaccaaaggtatcttccacaaaggtaacagactgggttgac ccatcatttgatgattttctagagtgtagtggcgtctctactattactgccacatcatta ggtgtgaataactcaagtcatagaagaaaaaatgggccttctacattagaaagcagcaga tttccagcgagaaaaagaggaaatctatcttccttagaacagatttatggtttagaaaat tcaaaagaatatctgtctgaaaatgaaccatgggtggataaatataaaccagaaactcag catgaacttgctgtgcataaaaagaaaattgaagaagtcgaaacctggttaaaagctcaa gttttagaaaggcaaccaaaacagggtggatctattttattaataacaggtcctcctgga tgtggaaagacaacgaccttaaaaatactatcaaaggagcatggtattcaagtacaagag tggattaatccagttttaccagacttccaaaaagatgatttcaaggggatgtttaatact gaatcaagcttccatatgtttccctatcagtctcagatagcagttttcaaagagtttcta ctaagagcgacaaagtataacaagttacaaatgcttggagatgatctgagaactgataag aagataattctggttgaagatttacctaaccagttttatcgggattctcatactttacat gaagttctaaggaagtatgtgaggattggtcgatgtcctcttatatttataatctcggac agtctcagtggagataataatcaaaggttattgtttcccaaagaaattcaggaagagtgt tctatctcaaatattagtttcaaccctgtggcaccaacaattatgatgaaatttcttaat cgaatagtgactatagaagctaacaagaatggaggaaaaattactgtccctgacaaaact tctctagagttgctctgtcagggatgttctggtgatatcagaagtgcaataaacagcctc cagttttcttcttcaaaaggagaaaacaacttacggccaaggaaaaaaggaatgtcttta aaatcagatgctgtgctgtcaaaatcaaaacgaagaaaaaaacctgatagggtttttgaa aatcaagaggtccaagctattggtggcaaagatgtttctctgtttctcttcagagctttg gggaaaattctatattgtaaaagagcatctttaacagaattagactcacctcggttgccc tctcatttatcagaatatgaacgggatacattacttgttgaacctgaggaggtagtagaa atgtcacacatgcctggagacttatttaatttatatcttcaccaaaactacatagatttc ttcatggaaattgatgatattgtgagagccagtgaatttctgagttttgcagatatcctc agtggtgactggaatacacgctctttactcagggaatatagcacatctatagctacgaga ggtgtgatgcattccaacaaagcccgaggatatgctcattgccaaggaggaggatcaagt tttcgacccttgcacaaacctcagtggtttctaataaataaaaagtatcgggaaaattgc ctggcagcaaaagcactttttcctgacttctgcctaccagctttatgcctccaaactcag ctattgccataccttgctctactaaccattccaatgagaaatcaagctcagatttctttt atccaagatattggaaggctccctctgaagcgacactttggaagattgaaaatggaagcc ctgactgacagggaacatggaatgatagaccctgacagcggagatgaagcccagcttaat ggaggacattctgcagaggaatctctgggtgaacccactcaagccactgtgccggaaacc tggtctcttcctttgagtcagaatagtgccagtgaactgcctgctagccagccccagccc ttttcagcccaaggagacatggaagaaaacataataatagaagactacgagagtgatggg acatag

Homo sapiens (human): 5883 Help Entry 5883              CDS       T01001                                  Symbol RAD9A, RAD9 Name (RefSeq) RAD9 checkpoint clamp component A   KO K10994   cell cycle checkpoint control protein RAD9A [EC:3.1.11.2] Organism hsa  Homo sapiens (human) Pathway hsa04218   Cellular senescence Network nt06506  Double-strand break repair   Element N01451   ATR signaling Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     5883 (RAD9A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03400 DNA repair and recombination proteins [BR:hsa03400]     5883 (RAD9A) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.11  Exodeoxyribonucleases producing 5'-phosphomonoesters     3.1.11.2  exodeoxyribonuclease III      5883 (RAD9A) DNA repair and recombination proteins [BR:hsa03400]  Eukaryotic type   Check point factors    Rad9-Hus1-Rad1 complex     5883 (RAD9A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Rad9 Rad1 Motif Other DBs NCBI-GeneID:  5883 NCBI-ProteinID:  NP_004575 OMIM:  603761 HGNC:  9827 Ensembl:  ENSG00000172613 UniProt:  Q99638 Structure PDBPDBj LinkDB All DBs Position 11:67391986..67398412 Genome browser AA seq 391 aa AA seqDB search MKCLVTGGNVKVLGKAVHSLSRIGDELYLEPLEDGLSLRTVNSSRSAYACFLFAPLFFQQ YQAATPGQDLLRCKILMKSFLSVFRSLAMLEKTVEKCCISLNGRSSRLVVQLHCKFGVRK THNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFSPALAEVTLGIGRGRRVILRS YHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLKEFRGLLSFAESANLNLSIHF DAPGRPAIFTIKDSLLDGHFVLATLSDTDSHSQDLGSPERHQPVPQLQAHSTPHPDDFAN DDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSPGPHSEEEDEAEPSTVPGTPPPKK FRSLFFGSILAPVRSPQGPSPVLAEDSEGEG NT seq 1176 nt NT seq  +upstreamnt  +downstreamnt atgaagtgcctggtcacgggcggcaacgtgaaggtgctcggcaaggccgtccactccctg tcccgcatcggggacgagctctacctggaacccttggaggacgggctctccctccggacg gtgaactcctcccgctctgcctatgcctgctttctctttgccccgctcttcttccagcaa taccaggcagccacccctggtcaggacctgctgcgctgtaagatcctgatgaagtctttc ctgtctgtcttccgctcactggcgatgctggagaagacggtggaaaaatgctgcatctcc ctgaatggccggagcagccgcctggtggtccagctgcattgcaagttcggggtgcggaag actcacaacctgtccttccaggactgtgagtccctgcaggccgtcttcgacccagcctcg tgcccccacatgctccgcgccccagcacgggttctgggggaggctgttctgcccttctct cctgcactggctgaagtgacgctgggcattggccgtggccgcagggtcatcctgcgcagc taccacgaggaggaggcagacagcactgccaaagccatggtgactgagatgtgccttgga gaggaggatttccagcagctgcaggcccaggaaggggtggccatcactttctgcctcaag gaattccgggggctcctgagctttgcagagtcagcaaacttgaatcttagcattcatttt gatgctccaggcaggcccgccatcttcaccatcaaggactctttgctggacggccacttt gtcttggccacactctcagacaccgactcgcactcccaggacctgggctccccagagcgt caccagccagtgcctcagctccaggctcacagcacaccccacccggacgactttgccaat gacgacattgactcttacatgatcgccatggaaaccactataggcaatgagggctcgcgg gtgctgccctccatttccctttcacctggcccccagccccccaagagccccggtccccac tccgaggaggaagatgaggctgagcccagtacagtgcctgggactcccccacccaagaag ttccgctcactgttcttcggctccatcctggcccctgtacgctccccccagggccccagc cctgtgctggcggaagacagtgagggtgaaggctga

Homo sapiens (human): 5810 Help Entry 5810              CDS       T01001                                  Symbol RAD1, HRAD1, REC1 Name (RefSeq) RAD1 checkpoint DNA exonuclease   KO K02830   cell cycle checkpoint protein [EC:3.1.11.2] Organism hsa  Homo sapiens (human) Pathway hsa04218   Cellular senescence Network nt06506  Double-strand break repair   Element N01451   ATR signaling Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     5810 (RAD1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03400 DNA repair and recombination proteins [BR:hsa03400]     5810 (RAD1) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.11  Exodeoxyribonucleases producing 5'-phosphomonoesters     3.1.11.2  exodeoxyribonuclease III      5810 (RAD1) DNA repair and recombination proteins [BR:hsa03400]  Eukaryotic type   Check point factors    Rad9-Hus1-Rad1 complex     5810 (RAD1)    Rad17-Mec3-Ddc1 complex     5810 (RAD1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Rad1 Pro_3_hydrox_C Motif Other DBs NCBI-GeneID:  5810 NCBI-ProteinID:  NP_002844 OMIM:  603153 HGNC:  9806 Ensembl:  ENSG00000113456 UniProt:  O60671 Structure PDBPDBj LinkDB All DBs Position 5:complement(34905260..34915504) Genome browser AA seq 282 aa AA seqDB search MPLLTQQIQDEDDQYSLVASLDNVRNLSTILKAIHFREHATCFATKNGIKVTVENAKCVQ ANAFIQAGIFQEFKVQEESVTFRINLTVLLDCLSIFGSSPMPGTLTALRMCYQGYGYPLM LFLEEGGVVTVCKINTQEPEETLDFDFCSTNVINKIILQSEGLREAFSELDMTSEVLQIT MSPDKPYFRLSTFGNAGSSHLDYPKDSDLMEAFHCNQTQVNRYKISLLKPSTKALVLSCK VSIRTDNRGFLSLQYMIRNEDGQICFVEYYCCPDEEVPESES NT seq 849 nt NT seq  +upstreamnt  +downstreamnt atgccccttctgacccaacagatccaagacgaggatgatcagtacagccttgtggccagc cttgacaacgttaggaatctctccactatcttgaaagctattcatttccgagaacatgcc acgtgtttcgcaactaaaaatggtatcaaagtaacagtggaaaatgcaaagtgtgtgcaa gcaaatgcttttattcaggctggaatatttcaggagtttaaagttcaggaagagtctgtt acttttcgaattaatttaactgtccttttagactgtttatctatttttggatcaagtcct atgccagggactttaactgcacttcgaatgtgttaccaaggttatggttaccctttgatg ctgttcctggaagaaggaggagtggtgacagtctgcaaaatcaatacacaggaacctgag gagaccctggactttgatttctgcagcaccaatgttattaataaaattattctgcagtca gaggggctccgtgaagcattttctgaattggatatgacgagtgaagtcctacaaattacc atgtctcctgacaagccttatttcaggttatctacttttggaaatgcaggaagttcccac cttgactatcccaaagattctgatttgatggaagcatttcattgtaatcagacccaagtc aacagatacaagatttccttactgaaaccctctacaaaggcattagtcctatcttgtaag gtatctattcggacagataacagaggcttcctttcattacagtatatgattagaaatgaa gatggacaaatatgttttgtggaatattactgctgccctgatgaagaagttcctgaatct gagtcttga

Homo sapiens (human): 3364 Help Entry 3364              CDS       T01001                                  Symbol HUS1, hHUS1 Name (RefSeq) HUS1 checkpoint clamp component   KO K10903   HUS1 checkpoint protein Organism hsa  Homo sapiens (human) Pathway hsa04218   Cellular senescence Network nt06506  Double-strand break repair   Element N01451   ATR signaling Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     3364 (HUS1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03400 DNA repair and recombination proteins [BR:hsa03400]     3364 (HUS1) DNA repair and recombination proteins [BR:hsa03400]  Eukaryotic type   Check point factors    Rad9-Hus1-Rad1 complex     3364 (HUS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hus1 Motif Other DBs NCBI-GeneID:  3364 NCBI-ProteinID:  NP_004498 OMIM:  603760 HGNC:  5309 Ensembl:  ENSG00000136273 UniProt:  O60921 A4D2F2 Structure PDBPDBj LinkDB All DBs Position 7:complement(47963288..47979615) Genome browser AA seq 280 aa AA seqDB search MKFRAKIVDGACLNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGGVSMWCELEQ ENFFNEFQMEGVSAENNEIYLELTSENLSRALKTAQNARALKIKLTNKHFPCLTVSVELL SMSSSSRIVTHDIPIKVIPRKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEKMKNISNHL VIEANLDGELNLKIETELVCVTTHFKDLGNPPLASESTHEDRNVEHMAEVHIDIRKLLQF LAGQQVNPTKALCNIVNNKMVHFDLLHEDVSLQYFIPALS NT seq 843 nt NT seq  +upstreamnt  +downstreamnt atgaagtttcgggccaagatcgtggacggggcctgtctgaaccacttcacacgaatcagt aacatgatagccaagcttgccaaaacctgcaccctccgcatcagccctgataagcttaac ttcatcctttgtgacaagctggctaatggaggagtgagcatgtggtgtgagctggaacag gagaacttcttcaacgaatttcaaatggagggtgtctctgcagaaaacaatgagatttat ttagagctaacatcggaaaacttatctcgagccttgaagactgcccagaatgccagggct ttgaaaatcaaactgactaataaacactttccctgcctcacggtctccgtggagctgtta tctatgtcaagcagtagccgcattgtgacccatgacatccccataaaggtgattcctagg aaattgtggaaggacttacaagaaccggtggtcccagatcctgatgttagtatttattta ccagtcttgaagactatgaagagtgttgtggaaaaaatgaaaaacatcagcaatcacctt gttattgaagcaaacctagatggagaattgaatttgaaaatagaaactgaattagtatgt gttacaactcattttaaagatcttggaaatcctccattagcctctgaaagcacccatgag gacagaaacgtggaacacatggctgaagtgcacatagatattaggaagctcctacagttt cttgctggacaacaagtaaatcccacaaaggccttatgcaatattgtgaataacaagatg gtgcattttgatctgcttcatgaagacgtgtcccttcagtatttcatccctgcgctgtcc tag

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