Homo sapiens (human): 5917 Help Entry 5917              CDS       T01001                                  Symbol RARS1, ArgRS, DALRD1, HLD9, RARS Name (RefSeq) arginyl-tRNA synthetase 1   KO K01887   arginyl-tRNA synthetase [EC:6.1.1.19] Organism hsa  Homo sapiens (human) Pathway hsa00970   Aminoacyl-tRNA biosynthesis Disease H00679   Hypomyelinating leukodystrophy Brite KEGG Orthology (KO) [BR:hsa00001]  09120 Genetic Information Processing   09122 Translation    00970 Aminoacyl-tRNA biosynthesis     5917 (RARS1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01007 Amino acid related enzymes [BR:hsa01007]     5917 (RARS1)   09182 Protein families: genetic information processing    03016 Transfer RNA biogenesis [BR:hsa03016]     5917 (RARS1)    03029 Mitochondrial biogenesis [BR:hsa03029]     5917 (RARS1) Enzymes [BR:hsa01000]  6. Ligases   6.1  Forming carbon-oxygen bonds    6.1.1  Ligases forming aminoacyl-tRNA and related compounds     6.1.1.19  arginine---tRNA ligase      5917 (RARS1) Amino acid related enzymes [BR:hsa01007]  Aminoacyl-tRNA synthetase   Class I (G)    5917 (RARS1) Transfer RNA biogenesis [BR:hsa03016]  Eukaryotic type   Aminoacyl-tRNA synthetases (AARSs)    Multi-aminoacyl-tRNA synthetase complex (MSC)     5917 (RARS1)  Prokaryotic type    Other AARSs     5917 (RARS1) Mitochondrial biogenesis [BR:hsa03029]  Mitochondrial DNA transcription, translation, and replication factors   Mitochondrial transcription and translation factors    Other mitochondrial DNA transcription and translation factors     5917 (RARS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  tRNA-synt_1d DALR_1 Arg_tRNA_synt_N tRNA-synt_1e tRNA-synt_1 Motif Other DBs NCBI-GeneID:  5917 NCBI-ProteinID:  NP_002878 OMIM:  107820 HGNC:  9870 Ensembl:  ENSG00000113643 UniProt:  P54136 Structure PDBPDBj LinkDB All DBs Position 5:168486471..168519301 Genome browser AA seq 660 aa AA seqDB search MDVLVSECSARLLQQEEEIKSLTAEIDRLKNCGCLGASPNLEQLQEENLKLKYRLNILRK SLQAERNKPTKNMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMG ISQMLKTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLV NGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGD WGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGK NPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDG RKIVFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIF AAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEK ERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTR IRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDY IYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM NT seq 1983 nt NT seq  +upstreamnt  +downstreamnt atggacgtactggtgtctgagtgctccgcgcggctgctgcagcaggaagaagagattaaa tctctgactgctgaaattgaccggttgaaaaactgtggctgtttaggagcttctccaaat ttggagcagttacaagaagaaaatttaaaattaaagtatcgactgaatattcttcgaaag agtcttcaggcagaaaggaacaaaccaactaaaaatatgattaacattattagccgccta caagaggtctttggtcatgcaattaaggctgcatatccagatttggaaaatcctcctctg ctagtgacaccaagtcagcaggccaagtttggggactatcagtgtaatagtgctatgggt atttctcagatgctcaaaaccaaggaacagaaagttaatccaagagaaattgctgaaaac attaccaaacacctcccagacaatgaatgtattgaaaaagttgaaattgctggtcctggt tttattaatgtccacttaagaaaggattttgtatcagaacaattgaccagtcttctagtg aatggagttcaactacctgctctgggagagaataaaaaggttatagttgacttttcctcc cctaatatagctaaagagatgcatgtaggccacctgaggtcaactatcataggagagagt ataagccgcctctttgaatttgcagggtatgacgtgctcaggttaaatcatgtaggagac tgggggacccagtttggcatgctcatcgctcacctgcaagacaaatttccagattatcta acagtttcacctcctattggggatcttcaggtcttttataaggaatctaagaagaggttt gatactgaggaggaatttaagaagcgagcatatcagtgtgtagttctgctccagggtaaa aacccagatattacaaaagcttggaagcttatctgtgatgtctcccgccaagagttaaat aaaatctatgatgcattggacgtctctttaatagagagaggggaatccttctatcaagat aggatgaatgatattgtaaaggaatttgaagatagaggatttgtgcaggtggatgatggc agaaagattgtatttgtcccagggtgttccataccattaaccatagtaaaatcagatgga ggttatacctatgatacatctgacctggctgctattaaacaaagactatttgaggaaaaa gcagatatgattatctatgttgtggacaatggacaatctgtgcacttccagacaatattt gctgctgctcaaatgattggttggtatgaccctaaagtaactcgagtcttccatgctgga tttggtgtggtgctaggggaagacaagaaaaagtttaaaacacgttcgggtgaaacagtg cgcctcatggatcttctgggagaaggactaaaacgatccatggacaagttgaaggaaaaa gaaagagacaaggtcttaactgcagaggaattgaatgctgctcagacatccgttgcgtat ggctgcatcaaatatgctgacctttcccataaccggttgaatgactacatcttctccttt gacaaaatgctagatgacagaggaaatacagctgcttacttgttgtatgccttcactaga atcaggtctattgcacgtctggccaatattgatgaagaaatgctccaaaaagctgctcga gaaaccaagattcttttggatcatgagaaggaatggaaactaggccggtgcattttacgg ttccctgagattctgcaaaagattttagatgacttatttctccacactctctgtgattat atatatgagctggcaactgctttcacagagttctatgatagctgctactgtgtggagaaa gatagacagactggaaaaatattgaaggtgaacatgtggcgtatgctgctatgtgaagca gtagctgctgtcatggccaaggggtttgatatcctgggaataaaacctgtccaaaggatg taa

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