Homo sapiens (human): 5965
Help
Entry
5965 CDS
T01001
Symbol
RECQL, RECON, RECQL1, RecQ1
Name
(RefSeq) ATP-dependent DNA helicase Q1
KO
K10899
ATP-dependent DNA helicase Q1 [EC:
5.6.2.4
]
Organism
hsa
Homo sapiens (human)
Disease
H00296
Defects in RecQ helicases
H03004
RECON progeroid syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
hsa03400
]
5965 (RECQL)
Enzymes [BR:
hsa01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.4 DNA 3'-5' helicase
5965 (RECQL)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
RecQ family DNA helicases
5965 (RECQL)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DEAD
Helicase_C
RecQ_Zn_bind
ResIII
RQC
GPS2_interact
KOW
SKA2
FlgN
Motif
Other DBs
NCBI-GeneID:
5965
NCBI-ProteinID:
NP_002898
OMIM:
600537
HGNC:
9948
Ensembl:
ENSP00000416739.2
UniProt:
P46063
Structure
PDB
PDBj
LinkDB
All DBs
Position
12:complement(21468910..21501635)
Genome browser
AA seq
649 aa
AA seq
DB search
MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNE
YDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGKS
LCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNK
NSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGI
LKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDF
IEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKW
SANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGF
GDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHFDEVWNSEACNKMCDNCCK
DSAFERKNITEYCRDLIKILKQAEELNEKLTPLKLIDSWMGKGAAKLRVAGVVAPTLPRE
DLEKIIAHFLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRA
ESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDDA
NT seq
1950 nt
NT seq
+upstream
nt +downstream
nt
atggcgtccgtttcagctctaactgaggaactggattctataaccagtgagctacatgca
gtagaaattcaaattcaagaacttacggaaaggcaacaagagcttattcagaaaaaaaaa
gtcctgacaaagaaaataaagcagtgtttagaggattctgatgccggggcaagcaatgaa
tatgattcttcacctgccgcttggaataaagaagattttccatggtctggtaaagttaaa
gatattctgcaaaatgtctttaaactggaaaagttcagaccacttcagcttgaaactatt
aacgtaacaatggctggaaaggaggtatttcttgttatgcctacaggaggtggaaagagc
ttatgttaccagttaccagcattatgttcagatggttttacactcgtcatttgcccattg
atctctcttatggaagaccaattaatggttttaaaacaattaggaatttcagcaaccatg
ttaaatgcttctagttctaaggagcatgttaaatgggttcatgctgaaatggtaaataaa
aactccgagttaaagctgatttatgtgactccagagaaaattgcaaaaagcaaaatgttt
atgtcaagactagagaaagcctatgaagcaaggagatttactcgaattgctgtggatgaa
gttcactgctgtagtcagtggggacatgatttcagacctgattataaggcacttggtatc
ttaaagcggcagttccctaacgcatcactaattgggctgactgcaactgcaacaaatcac
gttttgacggatgctcagaaaattttgtgcattgaaaagtgttttacttttacagcttct
tttaataggccaaatctatattatgaggttcggcagaagccctcaaacactgaagatttt
attgaggatattgtaaagctcattaatgggagatacaaagggcaatcaggaatcatatat
tgtttttctcagaaagactctgaacaagttacggttagtttgcagaatctgggaattcat
gcaggtgcttaccatgccaatttggagccagaagataagaccacagttcatagaaaatgg
tcagccaatgaaattcaggtagtagtggcaactgttgcatttggtatgggaattgataag
ccagatgtgaggtttgttatccatcattcaatgagtaaatccatggaaaattattaccaa
gagagtggacgtgcaggtcgagatgacatgaaagcagactgtattttgtactacggcttt
ggagatatattcagaataagttcaatggtggtgatggaaaatgtgggacagcagaagctt
tatgagatggtatcatactgtcaaaacataagcaaatgtcgtcgtgtgttgatggctcaa
cattttgatgaagtatggaactcagaagcatgtaacaaaatgtgcgataactgctgtaaa
gacagtgcatttgaaagaaagaacataacagagtactgcagagatctaatcaagatcctg
aagcaggcagaggaactgaatgaaaaactcactccattgaaactgattgattcttggatg
ggaaagggtgcagcaaaactgagagtagcaggtgttgtggctcccacacttcctcgtgaa
gatctggagaagattattgcacactttctaatacagcagtatcttaaagaagactacagt
tttacagcttatgctaccatttcgtatttgaaaataggacctaaagctaatcttctgaac
aatgaggcacatgctattactatgcaagtgacaaagtccacgcagaactctttcagggct
gaatcgtctcaaacttgtcattctgaacaaggtgataaaaagatggaggaaaaaaattca
ggcaacttccagaagaaggctgcaaacatgcttcagcaatctggttctaagaatacagga
gctaagaaaagaaaaatcgatgatgcctga
DBGET
integrated database retrieval system
