Homo sapiens (human): 60676
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Entry
60676 CDS
T01001
Symbol
PAPPA2, PAPP-A2, PAPP-E, PAPPE, PLAC3, SSDA
Name
(RefSeq) pappalysin 2
KO
K08647
pappalysin-2 [EC:3.4.24.-]
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
60676 (PAPPA2)
Peptidases and inhibitors [BR:
hsa01002
]
Metallo peptidases
Family M43: cytophagalysin family
60676 (PAPPA2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Laminin_G_3
Sushi
Peptidase_M43
DUF4215
Notch
Laminin_G_2
Laminin_G_1
Reprolysin_3
DUF4953
Motif
Other DBs
NCBI-GeneID:
60676
NCBI-ProteinID:
NP_064714
OMIM:
619485
HGNC:
14615
Ensembl:
ENSG00000116183
UniProt:
Q9BXP8
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:176463175..176845601
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AA seq
1791 aa
AA seq
DB search
MMCLKILRISLAILAGWALCSANSELGWTRKKSLVEREHLNQVLLEGERCWLGAKVRRPR
ASPQHHLFGVYPSRAGNYLRPYPVGEQEIHHTGRSKPDTEGNAVSLVPPDLTENPAGLRG
AVEEPAAPWVGDSPIGQSELLGDDDAYLGNQRSKESLGEAGIQKGSAMAATTTTAIFTTL
NEPKPETQRRGWAKSRQRRQVWKRRAEDGQGDSGISSHFQPWPKHSLKHRVKKSPPEESN
QNGGEGSYREAETFNSQVGLPILYFSGRRERLLLRPEVLAEIPREAFTVEAWVKPEGGQN
NPAIIAGVFDNCSHTVSDKGWALGIRSGKDKGKRDARFFFSLCTDRVKKATILISHSRYQ
PGTWTHVAATYDGRHMALYVDGTQVASSLDQSGPLNSPFMASCRSLLLGGDSSEDGHYFR
GHLGTLVFWSTALPQSHFQHSSQHSSGEEEATDLVLTASFEPVNTEWVPFRDEKYPRLEV
LQGFEPEPEILSPLQPPLCGQTVCDNVELISQYNGYWPLRGEKVIRYQVVNICDDEGLNP
IVSEEQIRLQHEALNEAFSRYNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPEC
EHPLTGYDGGDCRLQGRCYSWNRRDGLCHVECNNMLNDFDDGDCCDPQVADVRKTCFDPD
SPKRAYMSVKELKEALQLNSTHFLNIYFASSVREDLAGAATWPWDKDAVTHLGGIVLSPA
YYGMPGHTDTMIHEVGHVLGLYHVFKGVSERESCNDPCKETVPSMETGDLCADTAPTPKS
ELCREPEPTSDTCGFTRFPGAPFTNYMSYTDDNCTDNFTPNQVARMHCYLDLVYQQWTES
RKPTPIPIPPMVIGQTNKSLTIHWLPPISGVVYDRASGSLCGACTEDGTFRQYVHTASSR
RVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPEVHLYHMNMTVPCPTEGCSLELLFQHP
VQADTLTLWVTSFFMESSQVLFDTEILLENKESVHLGPLDTFCDIPLTIKLHVDGKVSGV
KVYTFDERIEIDAALLTSQPHSPLCSGCRPVRYQVLRDPPFASGLPVVVTHSHRKFTDVE
VTPGQMYQYQVLAEAGGELGEASPPLNHIHGAPYCGDGKVSERLGEECDDGDLVSGDGCS
KVCELEEGFNCVGEPSLCYMYEGDGICEPFERKTSIVDCGIYTPKGYLDQWATRAYSSHE
DKKKCPVSLVTGEPHSLICTSYHPDLPNHRPLTGWFPCVASENETQDDRSEQPEGSLKKE
DEVWLKVCFNRPGEARAIFIFLTTDGLVPGEHQQPTVTLYLTDVRGSNHSLGTYGLSCQH
NPLIINVTHHQNVLFHHTTSVLLNFSSPRVGISAVALRTSSRIGLSAPSNCISEDEGQNH
QGQSCIHRPCGKQDSCPSLLLDHADVVNCTSIGPGLMKCAITCQRGFALQASSGQYIRPM
QKEILLTCSSGHWDQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQ
GLSPWLTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGY
YVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVL
NCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNSVEYKCEQGYGIGAVCSPL
CVIPPSDPVMLPENITADTLEHWMEPVKVQSIVCTGRRQWHPDPVLVHCIQSCEPFQADG
WCDTINNRAYCHYDGGDCCSSTLSSKKVIPFAADCDLDECTCRDPKAEENQ
NT seq
5376 nt
NT seq
+upstream
nt +downstream
nt
atgatgtgcttaaagatcctaagaataagcctggcgattttggctgggtgggcactctgt
tctgccaactctgagctgggctggacacgcaagaaatccttggttgagagggaacacctg
aatcaggtgctgttggaaggagaacgttgttggctgggggccaaggttcgaagacccaga
gcttctccacagcatcacctctttggagtctaccccagcagggctgggaactacctaagg
ccctaccccgtgggggagcaagaaatccatcatacaggacgcagcaaaccagacactgaa
ggaaatgctgtgagccttgttcccccagacctgactgaaaatccagcaggactgaggggt
gcagttgaagagccggctgccccatgggtaggggatagtcctattgggcaatctgagctg
ctgggagatgatgacgcttatctcggcaatcaaagatccaaggagtctctaggtgaggcc
gggattcagaaaggctcagccatggctgccactactaccaccgccattttcacaaccctg
aacgaacccaaaccagagacccaaaggaggggctgggccaagtccaggcagcgtcgccaa
gtgtggaagaggcgggcggaagatgggcagggagactccggtatctcttcacatttccaa
ccttggcccaagcattcccttaaacacagggtcaaaaagagtccaccggaggaaagcaac
caaaatggtggagagggctcctaccgagaagcagagacctttaactcccaagtaggactg
cccatcttatacttctctgggaggcgggagcggctgctgctgcgtccagaagtgctggct
gagattccccgggaggcgttcacagtggaagcctgggttaaaccggagggaggacagaac
aacccagccatcatcgcaggtgtgtttgataactgctcccacactgtcagtgacaaaggc
tgggccctggggatccgctcagggaaggacaagggaaagcgggatgctcgcttcttcttc
tccctctgcaccgaccgcgtgaagaaagccaccatcttgattagccacagtcgctaccaa
ccaggcacatggacccatgtggcagccacttacgatggacggcacatggccctgtatgtg
gatggcactcaggtggctagcagtctagaccagtctggtcccctgaacagccccttcatg
gcatcttgccgctctttgctcctggggggagacagctctgaggatgggcactatttccgt
ggacacctgggcacactggttttctggtcgaccgccctgccacaaagccattttcagcac
agttctcagcattcaagtggggaggaggaagcgactgacttggtcctgacagcgagcttt
gagcctgtgaacacagagtgggttccctttagagatgagaagtacccacgacttgaggtt
ctccagggctttgagccagagcctgagattctgtcgcctttgcagcccccactctgtggg
caaacagtctgtgacaatgtggaattgatctcccagtacaatggatactggccccttcgg
ggagagaaggtgatacgctaccaggtggtgaacatctgtgatgatgagggcctaaacccc
attgtgagtgaggagcagattcgtctgcagcacgaggcactgaatgaggccttcagccgc
tacaacatcagctggcagctgagcgtccaccaggtccacaattccaccctgcgacaccgg
gttgtgcttgtgaactgtgagcccagcaagattggcaatgaccattgtgaccccgagtgt
gagcacccactcacaggctatgatgggggtgactgccgcctgcagggccgctgctactcc
tggaaccgcagggatgggctctgtcacgtggagtgtaacaacatgctgaacgactttgac
gacggagactgctgcgacccccaggtggctgatgtgcgcaagacctgctttgaccctgac
tcacccaagagggcatacatgagtgtgaaggagctgaaggaggccctgcagctgaacagt
actcacttcctcaacatctactttgccagctcagtgcgggaagaccttgcaggtgctgcc
acctggccttgggacaaggacgctgtcactcacctgggtggcattgtcctcagcccagca
tattatgggatgcctggccacaccgacaccatgatccatgaagtgggacatgttctggga
ctctaccatgtctttaaaggagtcagtgaaagagaatcctgcaatgacccctgcaaggag
acagtgccatccatggaaacgggagacctctgtgccgacaccgcccccactcccaagagt
gagctgtgccgggaaccagagcccactagtgacacctgtggcttcactcgcttcccaggg
gctccgttcaccaactacatgagctacacggatgataactgcactgacaacttcactcct
aaccaagtggcccgaatgcattgctatttggacctagtctatcagcagtggactgaaagc
agaaagcccacccccatccccattccacctatggtcatcggacagaccaacaagtccctc
actatccactggctgcctcctattagtggagttgtatatgacagggcctcaggcagcttg
tgtggcgcttgcactgaagatgggacctttcgtcagtatgtgcacacagcttcctcccgg
cgggtgtgtgactcctcaggttattggaccccagaggaggctgtggggcctcctgatgtg
gatcagccctgcgagccaagcttacaggcctggagccctgaggtccacctgtaccacatg
aacatgacggtcccctgccccacagaaggctgtagcttggagctgctcttccaacacccg
gtccaagccgacaccctcaccctgtgggtcacttccttcttcatggagtcctcgcaggtc
ctctttgacacagagatcttgctggaaaacaaggagtcagtgcacctgggccccttagac
actttctgtgacatcccactcaccatcaaactgcacgtggatgggaaggtgtcgggggtg
aaagtctacacctttgatgagaggatagagattgatgcagcactcctgacttctcagccc
cacagtcccttgtgctctggctgcaggcctgtgaggtaccaggttctccgcgatccccca
tttgccagtggtttgcccgtggtggtgacacattctcacaggaagttcacggacgtggag
gtcacacctggacagatgtatcagtaccaagttctagctgaagctggaggagaactggga
gaagcttcgcctcctctgaaccacattcatggagctccttattgtggagatgggaaggtg
tcagagagactgggagaagagtgtgatgatggagaccttgtgagcggagatggctgctcc
aaggtgtgtgagctggaggaaggtttcaactgtgtaggagagccaagcctttgctacatg
tatgagggagatggcatatgtgaaccttttgagagaaaaaccagcattgtagactgtggc
atctacactcccaaaggatacttggatcaatgggctacccgggcttactcctctcatgaa
gacaagaagaagtgtcctgtttccttggtaactggagaacctcattccctaatttgcaca
tcataccatccagatttacccaaccaccgtcccctaactggctggtttccctgtgttgcc
agtgaaaatgaaactcaggatgacaggagtgaacagccagaaggtagcctgaagaaagag
gatgaggtttggctcaaagtgtgtttcaatagaccaggagaggccagagcaatttttatt
tttttgacaactgatggcctagttcccggagagcatcagcagccgacagtgactctctac
ctgaccgatgtccgtggaagcaaccactctcttggaacctatggactgtcatgccagcat
aatccactgattatcaatgtgacccatcaccagaatgtccttttccaccataccacctca
gtgctgctgaatttctcatccccacgggtcggcatctcagctgtggctctaaggacatcc
tcccgcattggtctttcggctcccagtaactgcatctcagaggacgaggggcagaatcat
cagggacagagctgtatccatcggccctgtgggaagcaggacagctgtccgtcattgctg
cttgatcatgctgatgtggtgaactgtacctctataggcccaggtctcatgaagtgtgct
atcacttgtcaaaggggatttgcccttcaggccagcagtgggcagtacatcaggcccatg
cagaaggaaattctgctcacatgttcttctgggcactgggaccagaatgtgagctgcctt
cccgtggactgcggtgttcccgacccgtctttggtgaactatgcaaacttctcctgctca
gagggaaccaaatttctgaaacgctgctcaatctcttgtgtcccaccagccaagctgcaa
ggactgagcccatggctgacatgtcttgaagatggtctctggtctctccctgaagtctac
tgcaagttggagtgtgatgctccccctattattctgaatgccaacttgctcctgcctcac
tgcctccaggacaaccacgacgtgggcaccatctgcaaatatgaatgcaaaccagggtac
tatgtggcagaaagtgcagagggtaaagtcaggaacaagctcctgaagatacaatgcctg
gaaggtggaatctgggagcaaggcagctgcattcctgtggtgtgtgagccaccccctcct
gtgtttgaaggcatgtatgaatgtaccaatggcttcagcctggacagccagtgtgtgctc
aactgtaaccaggaacgtgaaaagcttcccatcctctgcactaaagagggcctgtggacc
caggagtttaagttgtgtgagaatctgcaaggagaatgcccaccacccccctcagagctg
aattctgtggagtacaaatgtgaacaaggatatgggattggtgcagtgtgttccccattg
tgtgtaatcccccccagtgaccccgtgatgctacctgagaatatcactgctgacactctg
gagcactggatggaacctgtcaaagtccagagcattgtgtgcactggccggcgtcaatgg
cacccagaccccgtcttagtccactgcatccagtcatgtgagcccttccaagcagatggt
tggtgtgacactatcaacaaccgagcctactgccactatgacgggggagactgctgctct
tccacactctcctccaagaaggtcattccatttgctgctgactgtgacctggatgagtgc
acctgccgggaccccaaggcagaagaaaatcagtaa
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