Homo sapiens (human): 6401 Help Entry 6401              CDS       T01001                                  Gene name SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 Definition (RefSeq) selectin E   KO K06494   selectin, endothelial cell Organism hsa  Homo sapiens (human) Pathway hsa04514   Cell adhesion molecules hsa04668   TNF signaling pathway hsa04933   AGE-RAGE signaling pathway in diabetic complications hsa05143   African trypanosomiasis hsa05144   Malaria hsa05417   Lipid and atherosclerosis hsa05418   Fluid shear stress and atherosclerosis Drug target Bimosiamose disodium:  D03114 Rivipansel:  D10487 Uproleselan (DG02990):  D11310 D11332 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     6401 (SELE)   09133 Signaling molecules and interaction    04514 Cell adhesion molecules     6401 (SELE)  09160 Human Diseases   09174 Infectious disease: parasitic    05144 Malaria     6401 (SELE)    05143 African trypanosomiasis     6401 (SELE)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     6401 (SELE)    05418 Fluid shear stress and atherosclerosis     6401 (SELE)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     6401 (SELE)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04515 Cell adhesion molecules [BR:hsa04515]     6401 (SELE)    04090 CD molecules [BR:hsa04090]     6401 (SELE)    04091 Lectins [BR:hsa04091]     6401 (SELE) Cell adhesion molecules [BR:hsa04515]  Selectins   Selectin family    6401 (SELE) CD molecules [BR:hsa04090]  Proteins   6401 (SELE) Lectins [BR:hsa04091]  C-Type lectins   Group 4: Selectins    6401 (SELE) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Sushi Lectin_C EGF hEGF EGF_2 Plasmod_Pvs28 Motif Other DBs NCBI-GeneID:  6401 NCBI-ProteinID:  NP_000441 OMIM:  131210 HGNC:  10718 Ensembl:  ENSG00000007908 Vega:  OTTHUMG00000034851 Pharos:  P16581(Tchem) UniProt:  P16581 LinkDB All DBs Structure PDB:  1G1T 4C16 1ESL 6EYI 6EYJ 6EYK 4CSY Thumbnails Position 1q24.2 AA seq 610 aa AA seqDB search MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLN SILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREK DVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNC TALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVV ECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK AVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIP VCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDN EKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQ WTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHW SGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESD GSYQKPSYIL NT seq 1833 nt NT seq  +upstreamnt  +downstreamnt atgattgcttcacagtttctctcagctctcactttggtgcttctcattaaagagagtgga gcctggtcttacaacacctccacggaagctatgacttatgatgaggccagtgcttattgt cagcaaaggtacacacacctggttgcaattcaaaacaaagaagagattgagtacctaaac tccatattgagctattcaccaagttattactggattggaatcagaaaagtcaacaatgtg tgggtctgggtaggaacccagaaacctctgacagaagaagccaagaactgggctccaggt gaacccaacaataggcaaaaagatgaggactgcgtggagatctacatcaagagagaaaaa gatgtgggcatgtggaatgatgagaggtgcagcaagaagaagcttgccctatgctacaca gctgcctgtaccaatacatcctgcagtggccacggtgaatgtgtagagaccatcaataat tacacttgcaagtgtgaccctggcttcagtggactcaagtgtgagcaaattgtgaactgt acagccctggaatcccctgagcatggaagcctggtttgcagtcacccactgggaaacttc agctacaattcttcctgctctatcagctgtgataggggttacctgccaagcagcatggag accatgcagtgtatgtcctctggagaatggagtgctcctattccagcctgcaatgtggtt gagtgtgatgctgtgacaaatccagccaatgggttcgtggaatgtttccaaaaccctgga agcttcccatggaacacaacctgtacatttgactgtgaagaaggatttgaactaatggga gcccagagccttcagtgtacctcatctgggaattgggacaacgagaagccaacgtgtaaa gctgtgacatgcagggccgtccgccagcctcagaatggctctgtgaggtgcagccattcc cctgctggagagttcaccttcaaatcatcctgcaacttcacctgtgaggaaggcttcatg ttgcagggaccagcccaggttgaatgcaccactcaagggcagtggacacagcaaatccca gtttgtgaagctttccagtgcacagccttgtccaaccccgagcgaggctacatgaattgt cttcctagtgcttctggcagtttccgttatgggtccagctgtgagttctcctgtgagcag ggttttgtgttgaagggatccaaaaggctccaatgtggccccacaggggagtgggacaac gagaagcccacatgtgaagctgtgagatgcgatgctgtccaccagcccccgaagggtttg gtgaggtgtgctcattcccctattggagaattcacctacaagtcctcttgtgccttcagc tgtgaggagggatttgaattacatggatcaactcaacttgagtgcacatctcagggacaa tggacagaagaggttccttcctgccaagtggtaaaatgttcaagcctggcagttccggga aagatcaacatgagctgcagtggggagcccgtgtttggcactgtgtgcaagttcgcctgt cctgaaggatggacgctcaatggctctgcagctcggacatgtggagccacaggacactgg tctggcctgctacctacctgtgaagctcccactgagtccaacattcccttggtagctgga ctttctgctgctggactctccctcctgacattagcaccatttctcctctggcttcggaaa tgcttacggaaagcaaagaaatttgttcctgccagcagctgccaaagccttgaatcagat ggaagctaccaaaagccttcttacatcctttaa

DBGET integrated database retrieval system