Homo sapiens (human): 6401
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Entry
6401 CDS
T01001
Symbol
SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2, selectin-e
Name
(RefSeq) selectin E
KO
K06494
selectin, endothelial cell
Organism
hsa
Homo sapiens (human)
Pathway
hsa04514
Cell adhesion molecules
hsa04668
TNF signaling pathway
hsa04933
AGE-RAGE signaling pathway in diabetic complications
hsa05143
African trypanosomiasis
hsa05144
Malaria
hsa05417
Lipid and atherosclerosis
hsa05418
Fluid shear stress and atherosclerosis
Drug target
Bimosiamose disodium:
D03114
Rivipansel:
D10487
Uproleselan (
DG02990
):
D11310
D11332
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
6401 (SELE)
09133 Signaling molecules and interaction
04514 Cell adhesion molecules
6401 (SELE)
09160 Human Diseases
09174 Infectious disease: parasitic
05144 Malaria
6401 (SELE)
05143 African trypanosomiasis
6401 (SELE)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
6401 (SELE)
05418 Fluid shear stress and atherosclerosis
6401 (SELE)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
6401 (SELE)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04515 Cell adhesion molecules [BR:
hsa04515
]
6401 (SELE)
04090 CD molecules [BR:
hsa04090
]
6401 (SELE)
04091 Lectins [BR:
hsa04091
]
6401 (SELE)
Cell adhesion molecules [BR:
hsa04515
]
Selectins
Selectin family
6401 (SELE)
CD molecules [BR:
hsa04090
]
Proteins
6401 (SELE)
Lectins [BR:
hsa04091
]
C-Type lectins
Group 4: Selectins
6401 (SELE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Sushi
Lectin_C
EGF
hEGF
EGF_2
Plasmod_Pvs28
EGF_3
Motif
Other DBs
NCBI-GeneID:
6401
NCBI-ProteinID:
NP_000441
OMIM:
131210
HGNC:
10718
Ensembl:
ENSG00000007908
Pharos:
P16581
(Tchem)
UniProt:
P16581
Structure
PDB
LinkDB
All DBs
Position
1:complement(169722640..169734079)
Genome browser
AA seq
610 aa
AA seq
DB search
MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLN
SILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREK
DVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNC
TALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVV
ECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK
AVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIP
VCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDN
EKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQ
WTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHW
SGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESD
GSYQKPSYIL
NT seq
1833 nt
NT seq
+upstream
nt +downstream
nt
atgattgcttcacagtttctctcagctctcactttggtgcttctcattaaagagagtgga
gcctggtcttacaacacctccacggaagctatgacttatgatgaggccagtgcttattgt
cagcaaaggtacacacacctggttgcaattcaaaacaaagaagagattgagtacctaaac
tccatattgagctattcaccaagttattactggattggaatcagaaaagtcaacaatgtg
tgggtctgggtaggaacccagaaacctctgacagaagaagccaagaactgggctccaggt
gaacccaacaataggcaaaaagatgaggactgcgtggagatctacatcaagagagaaaaa
gatgtgggcatgtggaatgatgagaggtgcagcaagaagaagcttgccctatgctacaca
gctgcctgtaccaatacatcctgcagtggccacggtgaatgtgtagagaccatcaataat
tacacttgcaagtgtgaccctggcttcagtggactcaagtgtgagcaaattgtgaactgt
acagccctggaatcccctgagcatggaagcctggtttgcagtcacccactgggaaacttc
agctacaattcttcctgctctatcagctgtgataggggttacctgccaagcagcatggag
accatgcagtgtatgtcctctggagaatggagtgctcctattccagcctgcaatgtggtt
gagtgtgatgctgtgacaaatccagccaatgggttcgtggaatgtttccaaaaccctgga
agcttcccatggaacacaacctgtacatttgactgtgaagaaggatttgaactaatggga
gcccagagccttcagtgtacctcatctgggaattgggacaacgagaagccaacgtgtaaa
gctgtgacatgcagggccgtccgccagcctcagaatggctctgtgaggtgcagccattcc
cctgctggagagttcaccttcaaatcatcctgcaacttcacctgtgaggaaggcttcatg
ttgcagggaccagcccaggttgaatgcaccactcaagggcagtggacacagcaaatccca
gtttgtgaagctttccagtgcacagccttgtccaaccccgagcgaggctacatgaattgt
cttcctagtgcttctggcagtttccgttatgggtccagctgtgagttctcctgtgagcag
ggttttgtgttgaagggatccaaaaggctccaatgtggccccacaggggagtgggacaac
gagaagcccacatgtgaagctgtgagatgcgatgctgtccaccagcccccgaagggtttg
gtgaggtgtgctcattcccctattggagaattcacctacaagtcctcttgtgccttcagc
tgtgaggagggatttgaattacatggatcaactcaacttgagtgcacatctcagggacaa
tggacagaagaggttccttcctgccaagtggtaaaatgttcaagcctggcagttccggga
aagatcaacatgagctgcagtggggagcccgtgtttggcactgtgtgcaagttcgcctgt
cctgaaggatggacgctcaatggctctgcagctcggacatgtggagccacaggacactgg
tctggcctgctacctacctgtgaagctcccactgagtccaacattcccttggtagctgga
ctttctgctgctggactctccctcctgacattagcaccatttctcctctggcttcggaaa
tgcttacggaaagcaaagaaatttgttcctgccagcagctgccaaagccttgaatcagat
ggaagctaccaaaagccttcttacatcctttaa
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