Homo sapiens (human): 64577
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Entry
64577 CDS
T01001
Symbol
ALDH8A1, ALDH12, DJ352A20.2
Name
(RefSeq) aldehyde dehydrogenase 8 family member A1
KO
K23234
aminomuconate-semialdehyde dehydrogenase [EC:
1.2.1.32
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00380
Tryptophan metabolism
hsa01100
Metabolic pathways
Module
hsa_M00038
Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09105 Amino acid metabolism
00380 Tryptophan metabolism
64577 (ALDH8A1)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.32 aminomuconate-semialdehyde dehydrogenase
64577 (ALDH8A1)
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Gene cluster
GFIT
Motif
Pfam:
Aldedh
DUF1487
Motif
Other DBs
NCBI-GeneID:
64577
NCBI-ProteinID:
NP_072090
OMIM:
606467
HGNC:
15471
Ensembl:
ENSG00000118514
UniProt:
Q9H2A2
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Position
6:complement(134917393..134950101)
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AA seq
487 aa
AA seq
DB search
MAGTNALLMLENFIDGKFLPCSSYIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPS
WSSRSPQERSRVLNQVADLLEQSLEEFAQAESKDQGKTLALARTMDIPRSVQNFRFFASS
SLHHTSECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPS
ELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERIT
QLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIY
SEFLKRFVEATRKWKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDK
LSLPARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLA
ATVWSSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEI
KTITVKH
NT seq
1464 nt
NT seq
+upstream
nt +downstream
nt
atggctggaacaaacgcacttttgatgctggaaaacttcatagatggaaaatttttacct
tgtagctcatatatagattcttacgacccatcaacaggggaagtgtattgcagagtgcca
aatagtggaaaagacgagatcgaagccgcggtcaaggccgccagagaagcctttcccagc
tggtcatcccgcagcccccaggagcgctcacgggtcctgaaccaggtggcggatttgctg
gagcagtccctggaggagtttgcccaggccgagtctaaagaccaagggaaaaccttagca
ctggcaagaaccatggacattccccggtctgtgcagaacttcaggttcttcgcttcctcc
agcctgcaccacacgtcagagtgcacgcagatggaccacctgggctgcatgcactacacg
gtgcgggccccggtgggagtcgctggtctgatcagcccctggaatttgccactctacttg
ctgacctggaagatagctccagcgatggctgcagggaacactgtgatagccaagcccagt
gagctgacttcagtgactgcgtggatgttgtgcaaactcctggataaagcaggtgttcca
ccaggtgtggtcaatattgtgtttggaaccgggcccagggtgggtgaggccctggtgtcc
cacccagaggtgcccctgatctccttcaccgggagccagcccaccgctgagcggatcacc
cagctgagcgctccccactgcaaaaagctctccctggagctggggggcaagaatcctgcc
atcatctttgaggacgccaacctggatgagtgcattccggcaaccgtcaggtccagcttt
gccaaccagggtgaaatctgtctctgtaccagcaggatctttgtccagaagagcatctat
agtgaatttttaaagagatttgtagaagctaccagaaagtggaaagtcggcattccctct
gatccactggtgagcataggtgctctgataagtaaagcacatttggagaaagtcagaagt
tacgtcaagagagctcttgctgaaggtgcccaaatttggtgcggtgagggagtggataag
ttgagcctccctgccaggaaccaggcaggctactttatgcttcccacggtgataacagac
attaaggatgaatcctgctgcatgacggaagagatatttggtccagtgacgtgtgtcgtc
ccctttgatagtgaagaggaggtgattgaaagagccaacaacgttaagtatgggctggcg
gctaccgtgtggtccagcaatgtggggcgcgtccaccgggtggctaagaagctgcagtct
ggcttggtctggaccaactgctggctcatcagggagctgaaccttcctttcggggggatg
aagagttctggaataggtagagagggagccaaggactcttacgacttcttcactgagatc
aaaaccatcaccgttaaacactga
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