Homo sapiens (human): 64857
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Entry
64857 CDS
T01001
Symbol
PLEKHG2, ARHGEF42, CLG, CTB-60E11.4, LDAMD
Name
(RefSeq) pleckstrin homology and RhoGEF domain containing G2
KO
K23859
pleckstrin homology domain-containing family G member 1/2/3
Organism
hsa
Homo sapiens (human)
Disease
H02377
Leukodystrophy and acquired microcephaly with or without dystonia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04990 Domain-containing proteins not elsewhere classified [BR:
hsa04990
]
64857 (PLEKHG2)
Domain-containing proteins not elsewhere classified [BR:
hsa04990
]
Pleckstrin homology (PH) domain-containing proteins
Other PH domain-containing proteins
64857 (PLEKHG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
Motif
Other DBs
NCBI-GeneID:
64857
NCBI-ProteinID:
NP_073746
OMIM:
611893
HGNC:
29515
Ensembl:
ENSG00000090924
UniProt:
Q9H7P9
LinkDB
All DBs
Position
19:39412669..39428415
Genome browser
AA seq
1386 aa
AA seq
DB search
MPEGAQGLSLSKPSPSLGCGRRGEVCDCGTVCETRTAPAAPTMASPRGSGSSTSLSTVGS
EGDPAPGPTPACSASRPEPLPGPPIRLHLSPVGIPGSARPSRLERVAREIVETERAYVRD
LRSIVEDYLGPLLDGGVLGLSVEQVGTLFANIEDIYEFSSELLEDLENSSSAGGIAECFV
QRSEDFDIYTLYCMNYPSSLALLRELSLSPPAALWLQERQAQLRHSLPLQSFLLKPVQRI
LKYHLLLQELGKHWAEGPGTGGREMVEEAIVSMTAVAWYINDMKRKQEHAARLQEVQRRL
GGWTGPELSAFGELVLEGAFRGGGGGGPRLRGGERLLFLFSRMLLVAKRRGLEYTYKGHI
FCCNLSVSESPRDPLGFKVSDLTIPKHRHLLQAKNQEEKRLWIHCLQRLFFENHPASIPA
KAKQVLLENSLHCAPKSKPVLEPLTPPLGSPRPRDARSFTPGRRNTAPSPGPSVIRRGRR
QSEPVKDPYVMFPQNAKPGFKHAGSEGELYPPESQPPVSGSAPPEDLEDAGPPTLDPSGT
SITEEILELLNQRGLRDPGPSTHDIPKFPGDSQVPGDSETLTFQALPSRDSSEEEEEEEE
GLEMDERGPSPLHVLEGLESSIAAEMPSIPCLTKIPDVPNLPEIPSRCEIPEGSRLPSLS
DISDVFEMPCLPAIPSVPNTPSLSSTPTLSCDSWLQGPLQEPAEAPATRRELFSGSNPGK
LGEPPSGGKAGPEEDEEGVSFTDFQPQDVTQHQGFPDELAFRSCSEIRSAWQALEQGQLA
RPGFPEPLLILEDSDLGGDSGSGKAGAPSSERTASRVRELARLYSERIQQMQRAETRASA
NAPRRRPRVLAQPQPSPCLPQEQAEPGLLPAFGHVLVCELAFPLTCAQESVPLGPAVWVQ
AAIPLSKQGGSPDGQGLHVSNLPKQDLPGIHVSAATLLPEQGGSRHVQAPAATPLPKQEG
PLHLQVPALTTFSDQGHPEIQVPATTPLPEHRSHMVIPAPSTAFCPEQGHCADIHVPTTP
ALPKEICSDFTVSVTTPVPKQEGHLDSESPTNIPLTKQGGSRDVQGPDPVCSQPIQPLSW
HGSSLDPQGPGDTLPPLPCHLPDLQIPGTSPLPAHGSHLDHRIPANAPLSLSQELPDTQV
PATTPLPLPQVLTDIWVQALPTSPKQGSLPDIQGPAAAPPLPEPSLTDTQVQKLTPSLEQ
KSLIDAHVPAATPLPERGGSLDIQGLSPTPVQTTMVLSKPGGSLASHVARLESSDLTPPH
SPPPSSRQLLGPNAAALSRYLAASYISQSLARRQGPGGGAPAASRGSWSSAPTSRASSPP
PQPQPPPPPARRLSYATTVNIHVGGGGRLRPAKAQVRLNHPALLASTQESMGLHRAQGAP
DAPFHM
NT seq
4161 nt
NT seq
+upstream
nt +downstream
nt
atgcctgagggagcccaaggactgagcctctccaaacctagcccaagcctcgggtgtggc
cgaagaggtgaagtgtgtgactgtggcaccgtgtgtgagactcggacagctcctgcagcc
cccaccatggcctccccccgaggttctgggagctccacatccctgagcacagtgggctct
gagggggatccagcccctgggcccactccagcctgctcagcctccaggccagagcccctt
ccagggcctcccatccgcctacatctctctccggtggggatcccaggttcagccagaccc
tcaaggctggagcgtgtggcccgggagatcgtggagacagaacgggcctatgtcagggac
ctccgcagcatcgtggaggactacctgggccctctgctggacggcggggtcctggggctg
agcgtggagcaggtgggcacgctgtttgccaacattgaggacatctacgagttcagcagc
gagctcctggaggacttggagaacagcagcagcgccgggggtattgccgagtgcttcgtg
cagaggagcgaggattttgacatctacacattgtactgcatgaactacccgagctccctg
gccctgctccgggagctgtcgttgtctccgccagcagccctgtggctgcaggagcgccag
gcccagcttcgccactcgctgcccctgcagagcttcctgctgaaacctgtccagcgcatt
ctcaagtaccatctgctgctgcaggaactagggaagcactgggcggagggcccaggcact
gggggtcgcgagatggtggaggaagctattgtgtccatgacagcggttgcctggtacatc
aacgacatgaagcgcaagcaggagcatgcagcgcgcctccaggaagtgcagcggcggctg
ggtggctggaccggaccagagctcagtgcttttggggaactggtgttggagggcgcgttc
cgaggaggcggagggggtggcccccggctacgagggggtgagcggctgctcttcctgttc
tctcggatgctgctggtggccaagcgcagggggctggagtacacctacaaaggccacatc
ttctgctgcaacctgagcgtgagcgagagtccccgagaccctctagggttcaaggtgtct
gatctgaccattcccaagcacagacacctgctccaggccaagaaccaagaagagaagagg
ctgtggattcactgtctccagcgcctcttctttgagaaccaccctgcctccatccctgcc
aaggcaaagcaagttctccttgaaaacagcctgcattgtgcccccaaaagtaagcctgtc
ctagagcccctgacacccccacttgggtctcctcgacctcgagatgctagaagttttacc
cctgggcgaaggaacacagctccatctcctgggccctctgtgattcgccgaggccgcagg
cagtctgagccggtgaaggacccttatgtcatgttcccacagaacgctaagcctggattc
aagcacgctggcagcgaaggggaactctaccctccagaatctcagccaccagtttcaggc
tctgcaccccctgaggacctggaggatgctggacccccaacactggacccctctgggacc
tcaatcactgaagaaatcctggaactgctgaatcagcgaggccttcgagatccagggccg
tccacccatgacattcccaagttccccggagactcccaggtgcctggcgacagcgaaacc
ctcacattccaagccctgcccagccgggactcttcagaagaggaggaggaggaagaggaa
gggctggagatggatgaacgggggccttccccactccacgtcctggaagggctcgaaagt
tccattgcagctgaaatgcccagcattccctgccttaccaaaattcctgacgtgcccaac
cttcctgaaattcccagccgctgtgaaattcccgaaggttctcgccttcctagtctctct
gacatttccgatgtttttgagatgccctgccttccagccatacctagtgtccccaacacc
cccagtctgtctagcactcccaccctctcctgtgactcctggctccaagggcctctgcag
gaaccagctgaggctccagccaccaggagagaactgttttctgggagcaatcctgggaaa
ctgggagagccgccttcaggaggcaaggcagggccagaggaggatgaagaaggggtatca
ttcacagacttccagccccaggatgtcacccaacatcagggattcccagatgagctggca
ttccgctcttgctcagaaatccggagcgcctggcaggcattggaacagggacagctggcc
cggccaggcttcccagagccactgctgatcctggaggattcggatctgggtggagacagc
gggagcgggaaggcaggagccccgagttcagaaaggacggcgtcccgagtgcgagagctg
gcccggctttacagcgagcggatccagcagatgcagcgggcggagactcgggcatcagcc
aatgccccgcgccgccggcctcgggttctggcccaaccccagccatccccctgtctgccc
caggagcaggcagagccagggctcctgcctgcctttggacacgtgctggtatgtgagctg
gccttcccactgacatgtgcccaggagtctgtccccctgggtcctgctgtctgggttcaa
gctgccatacctttgtcaaagcagggaggcagcccggatggccagggtctacatgtttcc
aatttgcctaagcaagaccttccgggcatccacgtttcagctgctacccttttgcctgag
caaggaggttcccggcatgtccaggctccagccgccacacctttgcccaagcaagaaggc
cccctgcacctccaggtgccggctcttacaactttctctgatcaaggccacccagaaatc
caagttccagccaccactcctttgcctgagcatagaagtcacatggttataccagctcca
tccaccgccttttgtcctgagcagggacactgtgcggacatccacgttcccaccactcca
gctttgcccaaggagatttgttctgatttcacagtttcagtcaccacccctgtgcccaag
caagaaggtcacctagacagcgagagcccaaccaatatcccactgacaaagcaaggaggt
tccagggatgttcagggcccagaccctgtctgcagtcaacccatccagcctttgtcttgg
catggaagcagcctggatccccagggcccaggcgacaccctaccacccttgccatgtcac
ctcccagaccttcagattccaggtacctcacctttgcctgcacatggaagccacctggac
catcggatcccagccaacgccccactgtctttgtcccaggagctcccagacactcaggtt
ccagctaccacacctttgcccctgccacaagtcctcacagacatctgggtccaagccctc
ccaacttcacccaagcagggaagcctcccagacatccagggtccagcggctgcacctcca
cttccggagccaagccttacagatacacaggtccaaaaactcacaccttcgttggagcag
aagagcctcatagatgcccatgttccagctgccacacctttacctgagagaggaggctct
ctagacattcagggcctctcacccaccccagttcagaccaccatggttttgtccaaacca
ggaggctccttagcctctcacgttgccaggttggagtcttcagacttgacgccacctcat
agtcccccaccttccagccgtcagctcctgggccccaatgcagctgccctctccagatac
ctggcagcctcatatatcagccagagcctggctcggcggcaggggcctgggggaggggcc
cccgcagcctcccggggctcctggtcctctgctcccacgtcacgggcatcttcgccgccc
ccccagccccagccaccacctcccccagccaggcggctcagctatgccacgacggttaac
atccacgtgggcgggggtgggcggctgcggccagccaaggcccaggtccggttgaaccac
cctgctctcttggcctccacacaggaatctatgggccttcacagggcccagggggctcct
gatgcccccttccacatgtga
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