Homo sapiens (human): 6506
Help
Entry
6506 CDS
T01001
Symbol
SLC1A2, DEE41, EAAT2, EIEE41, GLT-1, GLT1, HBGT
Name
(RefSeq) solute carrier family 1 member 2
KO
K05613
solute carrier family 1 (glial high affinity glutamate transporter), member 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04082
Neuroactive ligand signaling
hsa04721
Synaptic vesicle cycle
hsa04724
Glutamatergic synapse
hsa05014
Amyotrophic lateral sclerosis
hsa05016
Huntington disease
Network
nt06544
Neuroactive ligand signaling
Element
N01884
Transport of glutamate, EAAT
Disease
H00606
Early infantile epileptic encephalopathy
H01819
Early myoclonic encephalopathy
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
6506 (SLC1A2)
09150 Organismal Systems
09156 Nervous system
04724 Glutamatergic synapse
6506 (SLC1A2)
04721 Synaptic vesicle cycle
6506 (SLC1A2)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
6506 (SLC1A2)
05016 Huntington disease
6506 (SLC1A2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
6506 (SLC1A2)
Transporters [BR:
hsa02000
]
Solute carrier family (SLC)
SLC1: High-affinity glutamate and neutral amino acid transporter
6506 (SLC1A2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SDF
BPD_transp_1_N
Motif
Other DBs
NCBI-GeneID:
6506
NCBI-ProteinID:
NP_004162
OMIM:
600300
HGNC:
10940
Ensembl:
ENSG00000110436
UniProt:
P43004
Structure
PDB
PDBj
LinkDB
All DBs
Position
11:complement(35251205..35420507)
Genome browser
AA seq
574 aa
AA seq
DB search
MASTEGANNMPKQVEVRMHDSHLGSEEPKHRHLGLRLCDKLGKNLLLTLTVFGVILGAVC
GGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRA
MVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENL
VQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGM
NVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKI
IAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALG
TASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVL
DGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTS
VNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYA
AHNSVIVDECKVTLAANGKSADCSVEEEPWKREK
NT seq
1725 nt
NT seq
+upstream
nt +downstream
nt
atggcatctacggaaggtgccaacaatatgcccaagcaggtggaagtgcgaatgcacgac
agtcatcttggctcagaggaacccaagcaccggcacctgggcctgcgcctgtgtgacaag
ctggggaagaatctgctgctcaccctgacggtgtttggtgtcatcctgggagcagtgtgt
ggagggcttcttcgcttggcatctcccatccaccctgatgtggttatgttaatagccttc
ccaggggatatactcatgaggatgctaaaaatgctcattctccctctaatcatctccagc
ttaatcacagggttgtcaggcctggatgctaaggctagtggccgcttgggcacgagagcc
atggtgtattacatgtccacgaccatcattgctgcagtactgggggtcattctggtcttg
gctatccatccaggcaatcccaagctcaagaagcagctggggcctgggaagaagaatgat
gaagtgtccagcctggatgccttcctggaccttattcgaaatctcttccctgaaaacctt
gtccaagcctgctttcaacagattcaaacagtgacgaagaaagtcctggttgcaccaccg
ccggacgaggaggccaacgcaaccagcgctgttgtctctctgttgaacgagactgtgact
gaggtgccggaggagactaagatggttatcaagaagggcctggagttcaaggatgggatg
aacgtcttaggtctgatagggtttttcattgcttttggcatcgctatggggaagatggga
gatcaggccaagctgatggtggatttcttcaacattttgaatgagattgtaatgaagtta
gtgatcatgatcatgtggtactctcccctgggtatcgcctgcctgatctgtggaaagatc
attgcaatcaaggacttagaagtggttgctaggcaactggggatgtacatggtaacagtg
atcataggcctcatcatccacgggggcatctttctccccttgatttactttgtagtgacc
aggaaaaaccccttctccttttttgctggcattttccaagcttggatcactgccctgggc
accgcttccagtgctggaactttgcctgtcacctttcgttgcctggaagaaaatctgggg
attgataagcgtgtgactagattcgtccttcctgttggagcaaccattaacatggatggt
acagccctttatgaagcggtagccgccatctttatagcccaaatgaatggtgttgtcctg
gatggaggacagattgtgactgtaagcctcacagccaccctggcaagcgtcggcgcggcc
agtatccccagtgccgggctggtcaccatgctcctcattctgacagccgtgggcctgcca
acagaggacatcagcctgctggtggctgtggactggctgctggacaggatgagaacttca
gtcaatgttgtgggtgactcttttggggctgggatagtctatcacctctccaagtctgag
ctggataccattgactcccagcatcgagtgcatgaagatattgaaatgaccaagactcaa
tccatttatgatgacatgaagaaccacagggaaagcaactctaatcaatgtgtctatgct
gcacacaactctgtcatagtagatgaatgcaaggtaactctggcagccaatggaaagtca
gccgactgcagtgttgaggaagaaccttggaaacgtgagaaataa
Homo sapiens (human): 6512
Help
Entry
6512 CDS
T01001
Symbol
SLC1A7, AAAT, EAAT5
Name
(RefSeq) solute carrier family 1 member 7
KO
K05618
solute carrier family 1 (glutamate transporter), member 7
Organism
hsa
Homo sapiens (human)
Pathway
hsa04082
Neuroactive ligand signaling
hsa04721
Synaptic vesicle cycle
hsa04724
Glutamatergic synapse
Network
nt06544
Neuroactive ligand signaling
Element
N01884
Transport of glutamate, EAAT
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
6512 (SLC1A7)
09150 Organismal Systems
09156 Nervous system
04724 Glutamatergic synapse
6512 (SLC1A7)
04721 Synaptic vesicle cycle
6512 (SLC1A7)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
6512 (SLC1A7)
Transporters [BR:
hsa02000
]
Solute carrier family (SLC)
SLC1: High-affinity glutamate and neutral amino acid transporter
6512 (SLC1A7)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SDF
Motif
Other DBs
NCBI-GeneID:
6512
NCBI-ProteinID:
NP_006662
OMIM:
604471
HGNC:
10945
Ensembl:
ENSG00000162383
UniProt:
O00341
F1T0D3
LinkDB
All DBs
Position
1:complement(53087183..53142638)
Genome browser
AA seq
560 aa
AA seq
DB search
MVPHAILARGRDVCRRNGLLILSVLSVIVGCLLGFFLRTRRLSPQEISYFQFPGELLMRM
LKMMILPLVVSSLMSGLASLDAKTSSRLGVLTVAYYLWTTFMAVIVGIFMVSIIHPGSAA
QKETTEQSGKPIMSSADALLDLIRNMFPANLVEATFKQYRTKTTPVVKSPKVAPEEAPPR
RILIYGVQEENGSHVQNFALDLTPPPEVVYKSEPGTSDGMNVLGIVFFSATMGIMLGRMG
DSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDPRAVGKKLGFYSVTV
VCGLVLHGLFILPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNH
IDRRIARFVLPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAA
GIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKD
FARDTGTEKLLPCETKPVSLQEIVAAQQNGCVKSVAEASELTLGPTCPHHVPVQVEQDEE
LPAASLNHCTIQISELETNV
NT seq
1683 nt
NT seq
+upstream
nt +downstream
nt
atggtgccgcatgccatcttggcacgggggagggacgtgtgcaggcggaatggactcctc
atcctgtctgtgctgtctgtcatcgtgggctgcctcctcggcttcttcttgaggacccgg
cgcctctcaccacaggaaattagttacttccagttccctggagagctcctgatgaggatg
ctgaagatgatgatcctgccactggtggtctccagcttgatgtccggacttgcctccctg
gatgccaagacctctagccgcctgggcgtcctcaccgtggcgtactacctgtggaccacc
ttcatggctgtcatcgtgggcatcttcatggtctccatcatccacccaggcagcgcggcc
cagaaggagaccacggagcagagtgggaagcccatcatgagctcagccgatgccctgttg
gacctcatccggaacatgttcccagccaacctagtagaagccacattcaaacagtaccgc
accaagaccaccccagttgtcaagtcccccaaggtggcaccagaggaggcccctcctcgg
cggatcctcatctacggggtccaggaggagaatggctcccatgtgcagaacttcgccctg
gacctgaccccgccgcccgaggtcgtttacaagtcagagccgggcaccagcgatggcatg
aatgtgctgggcatcgtcttcttctctgccaccatgggcatcatgctgggccgcatgggt
gacagcggggcccccctggtcagcttctgccagtgcctcaatgagtcggtcatgaagatc
gtggcggtggctgtgtggtatttccccttcggcattgtgttcctcattgcgggtaagatc
ctggagatggacgaccccagggccgtcggcaagaagctgggcttctactcagtcaccgtg
gtgtgcgggctggtgctccacgggctctttatcctgcccctgctctacttcttcatcacc
aagaagaatcccatcgtcttcatccgtggcatcctgcaggctctgctcatcgcgctggcc
acctcctccagctcagccacactgcccatcaccttcaagtgcctgctggagaacaaccac
atcgaccggcgcatcgctcgcttcgtgctgcccgtgggtgccaccatcaacatggacggc
actgcgctctacgaggctgtggccgccatcttcatcgcccaggtcaacaactacgagctg
gactttggccagatcatcaccatcagtatcacagccactgcagccagcattggggcagct
ggcatcccccaggccggcctcgtcaccatggtcatcgtgctcacctccgtgggactgccc
accgatgacatcaccctcatcattgccgttgactgggctctggaccgtttccgcaccatg
attaacgtgctgggtgatgcgctggcagcggggatcatggcccatatatgtcggaaggat
tttgcccgggacacaggcaccgagaaactgctgccctgcgagaccaagccagtgagcctc
caggagatcgtggcagcccagcagaatggctgtgtgaagagtgtagccgaggcctccgag
ctcaccctgggccccacctgcccccaccacgtccccgttcaagtggagcaggatgaggag
ctgcccgctgcgagtctgaaccactgcaccatccagatcagtgagctggagaccaatgtc
tga
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integrated database retrieval system
