Homo sapiens (human): 6528
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Entry
6528 CDS
T01001
Symbol
SLC5A5, NIS, TDH1
Name
(RefSeq) solute carrier family 5 member 5
KO
K14385
solute carrier family 5 (sodium/iodide cotransporter), member 5
Organism
hsa
Homo sapiens (human)
Pathway
hsa04918
Thyroid hormone synthesis
Network
nt06322
TRH-TSH-TH signaling
Element
N00786
Transport of iodide
Disease
H00251
Thyroid dyshormonogenesis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09152 Endocrine system
04918 Thyroid hormone synthesis
6528 (SLC5A5)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
6528 (SLC5A5)
Transporters [BR:
hsa02000
]
Solute carrier family (SLC)
SLC5: Sodium glucose cotransporter
6528 (SLC5A5)
BRITE hierarchy
SSDB
Ortholog
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Gene cluster
GFIT
Motif
Pfam:
SSF
NdhL
Motif
Other DBs
NCBI-GeneID:
6528
NCBI-ProteinID:
NP_000444
OMIM:
601843
HGNC:
11040
Ensembl:
ENSG00000105641
UniProt:
Q92911
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Position
19:17871945..17895174
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AA seq
643 aa
AA seq
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MEAVETGERPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVG
LSLSASFMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEY
LEMRFSRAVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTA
VGGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRS
RYTFWTFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCG
IVMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSIN
AMAAVTVEDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVM
GVISGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVALGATLYPPSEQTMRVLPSSA
ARCVALSVNASGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTV
LCGALISCLTGPTKRSTLAPGLLWWDLARQTASVAPKEEVAILDDNLVKGPEELPTGNKK
PPGFLPTNEDRLFFLGQKELEGAGSWTPCVGHDGGRDQQETNL
NT seq
1932 nt
NT seq
+upstream
nt +downstream
nt
atggaggccgtggagaccggggaacggcccaccttcggagcctgggactacggggtcttt
gccctcatgctcctggtgtccactggcatcgggctgtgggtcgggctggctcggggcggg
cagcgcagcgctgaggacttcttcaccgggggccggcgcctggcggccctgcccgtgggc
ctgtcgctgtctgccagcttcatgtcggccgtgcaggtgctgggcgtgccgtcggaggcc
tatcgctatggcctcaagttcctctggatgtgcctgggccagcttctgaactcggtcctc
accgccctgctcttcatgcccgtcttctaccgcctgggcctcaccagcacctacgagtac
ctggagatgcgcttcagccgcgcagtgcggctctgcgggactttgcagtacattgtagcc
acgatgctgtacaccggcatcgtaatctacgcaccggccctcatcctgaaccaagtgacc
gggctggacatctgggcgtcgctcctgtccaccggaattatctgcaccttctacacggct
gtgggcggcatgaaggctgtggtctggactgatgtgttccaggtcgtggtgatgctaagt
ggcttctgggttgtcctggcacgcggtgtcatgcttgtgggcgggccccgccaggtgctc
acgctggcccagaaccactcccggatcaacctcatggactttaaccctgacccgaggagc
cgctatacattctggacttttgtggtgggtggcacgttggtgtggctctccatgtatggc
gtgaaccaggcgcaggtgcagcgctacgtggcttgccgcacagagaagcaggccaagctg
gccctgctcatcaaccaggtcggcctgttcctgatcgtgtccagcgctgcctgctgtggc
atcgtcatgtttgtgttctacactgactgcgaccctctcctcctggggcgcatctctgcc
ccagaccagtacatgcctctgctggtgctggacatcttcgaagatctgcctggagtcccc
gggcttttcctggcctgtgcttacagtggcaccctcagcacagcatccaccagcatcaat
gctatggctgcagtcactgtagaagacctcatcaaacctcggctgcggagcctggcaccc
aggaaactcgtgattatctccaaggggctctcactcatctacggatcggcctgtctcacc
gtggcagccctgtcctcactgctcggaggaggtgtccttcagggctccttcaccgtcatg
ggagtcatcagcggccccctgctgggagccttcatcttgggaatgttcctgccggcctgc
aacacaccgggcgtcctcgcgggactaggcgcgggcttggcgctgtcgctgtgggtggcc
ttgggcgccacgctgtacccacccagcgagcagaccatgagggtcctgccatcgtcggct
gcccgctgcgtggctctctcagtcaacgcctctggcctcctggacccggctctcctccct
gctaacgactccagcagggcccccagctcaggaatggacgccagccgacccgccttagct
gacagcttctatgccatctcctatctctattacggtgccctgggcacgctgaccactgtg
ctgtgcggagccctcatcagctgcctgacaggccccaccaagcgcagcaccctggccccg
ggattgttgtggtgggacctcgcacggcagacagcatcagtggcccccaaggaagaagtg
gccatcctggatgacaacttggtcaagggtcctgaagaactccccactggaaacaagaag
ccccctggcttcctgcccaccaatgaggatcgtctgtttttcttggggcagaaggagctg
gagggggctggctcttggaccccctgtgttggacatgatggtggtcgagaccagcaggag
acaaacctctga
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