Homo sapiens (human): 6554
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Entry
6554 CDS
T01001
Symbol
SLC10A1, FHCA2, NTCP
Name
(RefSeq) solute carrier family 10 member 1
KO
K14341
solute carrier family 10 (sodium/bile acid cotransporter), member 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04976
Bile secretion
hsa05161
Hepatitis B
Disease
H01935
Familial hypercholanemia
Drug target
Maralixibat (
DG02832
):
D10951
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
6554 (SLC10A1)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
6554 (SLC10A1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
6554 (SLC10A1)
Transporters [BR:
hsa02000
]
Solute carrier family (SLC)
SLC10: Sodium bile salt cotransporter
6554 (SLC10A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SBF
SBF_like
GAPT
Mem_trans
DUF2427
Motif
Other DBs
NCBI-GeneID:
6554
NCBI-ProteinID:
NP_003040
OMIM:
182396
HGNC:
10905
Ensembl:
ENSG00000100652
Pharos:
Q14973
(Tchem)
UniProt:
Q14973
B2RA41
Structure
PDB
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All DBs
Position
14:complement(69775416..69797241)
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AA seq
349 aa
AA seq
DB search
MEAHNASAPFNFTLPPNFGKRPTDLALSVILVFMLFFIMLSLGCTMEFSKIKAHLWKPKG
LAIALVAQYGIMPLTAFVLGKVFRLKNIEALAILVCGCSPGGNLSNVFSLAMKGDMNLSI
VMTTCSTFCALGMMPLLLYIYSRGIYDGDLKDKVPYKGIVISLVLVLIPCTIGIVLKSKR
PQYMRYVIKGGMIIILLCSVAVTVLSAINVGKSIMFAMTPLLIATSSLMPFIGFLLGYVL
SALFCLNGRCRRTVSMETGCQNVQLCSTILNVAFPPEVIGPLFFFPLLYMIFQLGEGLLL
IAIFWCYEKFKTPKDKTKMIYTAATTEETIPGALGNGTYKGEDCSPCTA
NT seq
1050 nt
NT seq
+upstream
nt +downstream
nt
atggaggcccacaacgcgtctgccccattcaacttcaccctgccacccaactttggcaag
cgccccacagacctggcactgagcgtcatcctggtgttcatgttgttcttcatcatgctc
tcgctgggctgcaccatggagttcagcaagatcaaggctcacttatggaagcctaaaggg
ctggccatcgccctggtggcacagtatggcatcatgcccctcacggcctttgtgctgggc
aaggtcttccggctgaagaacattgaggcactggccatcttggtctgtggctgctcacct
ggagggaacctgtccaatgtcttcagtctggccatgaagggggacatgaacctcagcatt
gtgatgaccacctgctccaccttctgtgcccttggcatgatgcctctcctcctgtacatc
tactccagggggatctatgatggggacctgaaggacaaggtgccctataaaggcatcgtg
atatcactggtcctggttctcattccttgcaccatagggatcgtcctcaaatccaaacgg
ccacaatacatgcgctatgtcatcaagggagggatgatcatcattctcttgtgcagtgtg
gccgtcacagttctctctgccatcaatgtggggaagagcatcatgtttgccatgacacca
ctcttgattgccacctcctccctgatgccttttattggctttctgctgggttatgttctc
tctgctctcttctgcctcaatggacggtgcagacgcactgtcagcatggagactggatgc
caaaatgtccaactctgttccaccatcctcaatgtggcctttccacctgaagtcattgga
ccacttttcttctttcccctcctctacatgattttccagcttggagaagggcttctcctc
attgccatattttggtgctatgagaaattcaagactcccaaggataaaacaaaaatgatc
tacacagctgccacaactgaagaaacaattccaggagctctgggaaatggcacctacaaa
ggggaggactgctccccttgcacagcctag
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