Homo sapiens (human): 6687
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Entry
6687 CDS
T01001
Symbol
SPG7, CAR, CMAR, PGN, SPG5C
Name
(RefSeq) SPG7 matrix AAA peptidase subunit, paraplegin
KO
K09552
spastic paraplegia 7 [EC:3.4.24.-]
Organism
hsa
Homo sapiens (human)
Disease
H00266
Hereditary spastic paraplegia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
6687 (SPG7)
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
hsa03110
]
6687 (SPG7)
Peptidases and inhibitors [BR:
hsa01002
]
Metallo peptidases
Family M41: FtsH endopeptidase family
6687 (SPG7)
Chaperones and folding catalysts [BR:
hsa03110
]
Other chaperones and cochaperones
AAA proteases
6687 (SPG7)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_M41
AAA
AAA_lid_3
FtsH_ext
AAA_5
AAA_17
nSTAND3
RuvB_N
AAA_22
AAA_16
AAA_2
Mg_chelatase
AAA_28
IstB_IS21
TIP49
ORC-CDC6-like
ABC_tran
AAA_14
PglZ
NACHT
NPHP3_N
RNA_helicase
Motif
Other DBs
NCBI-GeneID:
6687
NCBI-ProteinID:
NP_003110
OMIM:
602783
HGNC:
11237
Ensembl:
ENSG00000197912
UniProt:
Q9UQ90
Structure
PDB
PDBj
LinkDB
All DBs
Position
16:89508388..89557768
Genome browser
AA seq
795 aa
AA seq
DB search
MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
MSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLP
TLQERREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSV
HTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSITPRT
NAALGFAQMLPRDQHLFTKEQLFERMCMALGGRASEALSFNEVTSGAQDDLRKVTRIAYS
MVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRHTEKVLQD
NLDKLQALANALLEKEVINYEDIEALIGPPPHGPKKMIAPQRWIDAQREKQDLGEEETEE
TQQPPLGGEEPTWPK
NT seq
2388 nt
NT seq
+upstream
nt +downstream
nt
atggccgtgctgctgctgctgctccgtgccctccgccggggtccaggcccgggtcctcgg
ccgctgtggggcccaggcccggcctggagtccagggttccccgccaggcccgggaggggg
cggccgtacatggccagcaggcctccgggggacctcgccgaggctggaggccgagctctg
cagagcttacaattgagactgctaacccctacctttgaagggatcaacggattgttgttg
aaacaacatttagttcagaatccagtcagactctggcaacttttaggtggtactttctat
tttaacacctcaaggttgaagcagaagaataaggagaaggataagtcgaaggggaaggcg
cctgaagaggacgaagaggagaggagacgccgtgagcgggacgaccagatgtaccgagag
cggctgcgcaccttgctggtcatcgcggttgtcatgagcctcctgaatgctctcagcacc
agcggaggcagcatttcctggaacgactttgtccacgagatgctggccaagggcgaggtg
cagcgcgtccaggtggtgcctgagagcgacgtggtggaagtctacctgcaccctggagcc
gtggtgtttgggcggcctcggctagccttgatgtaccgaatgcaggttgcaaatattgac
aagtttgaagagaagcttcgagcagctgaagatgagctgaatatcgaggccaaggacagg
atcccagtttcctacaagcgaacaggattctttggaaatgccctgtactctgtggggatg
acggcagtgggcctggccatcctgtggtatgttttccgtctggccgggatgactggaagg
gaaggtggattcagtgcttttaatcagcttaaaatggctcgtttcaccattgtggatggg
aagatggggaaaggagtcagcttcaaagacgtggcaggaatgcacgaagccaaactggaa
gtccgcgagtttgtggattatctgaagagcccagaacgcttcctccagcttggcgccaag
gtcccaaagggcgcactgctgctcggcccccccggctgtgggaagacgctgctggccaag
gcggtggccacggaggctcaggtgcccttcctggcgatggccggcccagagttcgtggag
gtcattggaggcctcggcgctgcccgtgtgcggagcctctttaaggaagcccgagcccgg
gccccctgcatcgtctacatcgatgagatcgacgcggtgggcaagaagcgctccaccacc
atgtccggcttctccaacacggaggaggagcagacgctcaaccagcttctggtagaaatg
gatggaatgggtaccacagaccatgtcatcgtcctggcgtccacgaaccgagctgacatt
ttggacggtgctctgatgaggccaggccgactggaccggcacgtcttcattgatctcccc
acgctgcaggagaggcgggagatttttgagcagcacctgaagagcctgaagctgacccag
tccagcaccttttactcccagcgtctggcagagctgacaccaggattcagtggggctgac
atcgccaacatctgcaatgaggctgcgctgcacgcggcgcgggagggacacacttccgtg
cacactctcaacttcgagtacgccgtggagcgcgtcctcgcagggactgccaaaaagagc
aagatcctgtccaaggaagaacagaaagtggttgcgtttcatgagtcgggccacgccttg
gtgggctggatgctggagcacacggaggccgtgatgaaggtctccataacccctcggaca
aacgccgccctgggctttgctcagatgctccccagagaccagcacctcttcaccaaggag
cagctgtttgagcggatgtgcatggccctgggaggacgggcctcggaagcactgtccttc
aacgaggtcacttctggggcacaggacgacctgaggaaggtcacccgcatcgcctactcc
atggtgaagcagtttgggatggcacctggcatcgggcccatctccttccctgaggcgcag
gagggcctcatgggcatcgggcggcgccccttcagccaaggcctgcagcagatgatggac
catgaagcaagactgctggtggccaaggcctacagacacaccgagaaggtgctgcaggac
aacctggacaagttgcaggcgctggcaaacgcccttctggaaaaggaagtgataaactat
gaggacattgaggctctcattggcccgccgccccatgggccgaagaaaatgatcgcaccg
cagaggtggatcgacgcccagagggagaaacaggacttgggcgaggaggagaccgaagag
acccagcagcctccacttggaggcgaagagccgacttggcccaagtag
DBGET
integrated database retrieval system
