Homo sapiens (human): 6692
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Entry
6692 CDS
T01001
Symbol
SPINT1, HAI, HAI1, MANSC2
Name
(RefSeq) serine peptidase inhibitor, Kunitz type 1
KO
K15619
Kunitz-type protease inhibitor 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa05202
Transcriptional misregulation in cancer
hsa05215
Prostate cancer
Network
nt06240
Transcription (cancer)
nt06272
Prostate cancer
Element
N00129
TMPRSS2-ERG fusion to transcriptional repression
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
6692 (SPINT1)
09162 Cancer: specific types
05215 Prostate cancer
6692 (SPINT1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
6692 (SPINT1)
Peptidases and inhibitors [BR:
hsa01002
]
Peptidase inhibitors
Family I2: Kunitz - BPTI family
6692 (SPINT1)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Kunitz_BPTI
MANEC
K319L-like_PKD
Ldl_recept_a
Chordopox_A13L
Antimicrobial12
Motif
Other DBs
NCBI-GeneID:
6692
NCBI-ProteinID:
NP_857593
OMIM:
605123
HGNC:
11246
Ensembl:
ENSG00000166145
UniProt:
O43278
Structure
PDB
PDBj
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All DBs
Position
15:40844048..40858207
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AA seq
529 aa
AA seq
DB search
MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG
FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN
CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV
LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV
LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC
RGVQGGPLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNC
PDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFT
YGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVV
AILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL
NT seq
1590 nt
NT seq
+upstream
nt +downstream
nt
atggcccctgcgaggacgatggcccgcgcccgcctcgccccggccggcatccctgccgtc
gccttgtggcttctgtgcacgctcggcctccagggcacccaggccgggccaccgcccgcg
ccccctgggctgcccgcgggagccgactgcctgaacagctttaccgccggggtgcctggc
ttcgtgctggacaccaacgcctcggtcagcaacggagctaccttcctggagtcccccacc
gtgcgccggggctgggactgcgtgcgcgcctgctgcaccacccagaactgcaacttggcg
ctagtggagctgcagcccgaccgcggggaggacgccatcgccgcctgcttcctcatcaac
tgcctctacgagcagaacttcgtgtgcaagttcgcgcccagggagggcttcatcaactac
ctcacgagggaagtgtaccgctcctaccgccagctgcggacccagggctttggagggtct
gggatccccaaggcctgggcaggcatagacttgaaggtacaaccccaggaacccctggtg
ctgaaggatgtggaaaacacagattggcgcctactgcggggtgacacggatgtcagggta
gagaggaaagacccaaaccaggtggaactgtggggactcaaggaaggcacctacctgttc
cagctgacagtgactagctcagaccacccagaggacacggccaacgtcacagtcactgtg
ctgtccaccaagcagacagaagactactgcctcgcatccaacaaggtgggtcgctgccgg
ggctctttcccacgctggtactatgaccccacggagcagatctgcaagagtttcgtttat
ggaggctgcttgggcaacaagaacaactaccttcgggaagaagagtgcattctagcctgt
cggggtgtgcaaggtgggcctttgagaggcagctctggggctcaggcgactttcccccag
ggcccctccatggaaaggcgccatccagtgtgctctggcacctgtcagcccacccagttc
cgctgcagcaatggctgctgcatcgacagtttcctggagtgtgacgacacccccaactgc
cccgacgcctccgacgaggctgcctgtgaaaaatacacgagtggctttgacgagctccag
cgcatccatttccccagtgacaaagggcactgcgtggacctgccagacacaggactctgc
aaggagagcatcccgcgctggtactacaaccccttcagcgaacactgcgcccgctttacc
tatggtggttgttacggcaacaagaacaactttgaggaagagcagcagtgcctcgagtct
tgtcgcggcatctccaagaaggatgtgtttggcctgaggcgggaaatccccattcccagc
acaggctctgtggagatggctgtcgcagtgttcctggtcatctgcattgtggtggtggta
gccatcttgggttactgcttcttcaagaaccagagaaaggacttccacggacaccaccac
cacccaccacccacccctgccagctccactgtctccactaccgaggacacggagcacctg
gtctataaccacaccacgcggcccctctga
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