Homo sapiens (human): 6708
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Entry
6708 CDS
T01001
Symbol
SPTA1, EL2, HPP, HS3, SPH3, SPTA
Name
(RefSeq) spectrin alpha chain, erythrocytic 1
KO
K27408
spectrin alpha, erythrocytic
Organism
hsa
Homo sapiens (human)
Disease
H00230
Hereditary spherocytosis
H00231
Hereditary elliptocytosis
H01125
Hereditary pyropoikilocytosis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
6708 (SPTA1)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
Cross-linking proteins
6708 (SPTA1)
Intermediate filaments
Intermediate filament-binding proteins
6708 (SPTA1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Spectrin
EFhand_Ca_insen
SH3_1
SH3_9
EF-hand_7
EF-hand_6
SH3_2
EF-hand_1
SH3_10
Motif
Other DBs
NCBI-GeneID:
6708
NCBI-ProteinID:
NP_003117
OMIM:
182860
HGNC:
11272
Ensembl:
ENSP00000495214.1
UniProt:
P02549
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:complement(158610704..158686715)
Genome browser
AA seq
2419 aa
AA seq
DB search
MEQFPKETVVESSGPKVLETAEEIQERRQEVLTRYQSFKERVAERGQKLEDSYHLQVFKR
DADDLGKWIMEKVNILTDKSYEDPTNIQGKYQKHQSLEAEVQTKSRLMSELEKTREERFT
MGHSAHEETKAHIEELRHLWDLLLELTLEKGDQLLRALKFQQYVQECADILEWIGDKEAI
ATSVELGEDWERTEVLHKKFEDFQVELVAKEGRVVEVNQYANECAEENHPDLPLIQSKQN
EVNAAWERLRGLALQRQKALSNAANLQRFKRDVTEAIQWIKEKEPVLTSEDYGKDLVASE
GLFHSHKGLERNLAVMSDKVKELCAKAEKLTLSHPSDAPQIQEMKEDLVSSWEHIRALAT
SRYEKLQATYWYHRFSSDFDELSGWMNEKTAAINADELPTDVAGGEVLLDRHQQHKHEID
SYDDRFQSADETGQDLVNANHEASDEVREKMEILDNNWTALLELWDERHRQYEQCLDFHL
FYRDSEQVDSWMSRQEAFLENEDLGNSLGSAEALLQKHEDFEEAFTAQEEKIITVDKTAT
KLIGDDHYDSENIKAIRDGLLARRDALREKAATRRRLLKESLLLQKLYEDSDDLKNWINK
KKKLADDEDYKDIQNLKSRVQKQQVFEKELAVNKTQLENIQKTGQEMIEGGHYASDNVTT
RLSEVASLWEELLEATKQKGTQLHEANQQLQFENNAEDLQRWLEDVEWQVTSEDYGKGLA
EVQNRLRKHGLLESAVAARQDQVDILTDLAAYFEEIGHPDSKDIRARQESLVCRFEALKE
PLATRKKKLLDLLHLQLICRDTEDEEAWIQETEPSATSTYLGKDLIASKKLLNRHRVILE
NIASHEPRIQEITERGNKMVEEGHFAAEDVASRVKSLNQNMESLRARAARRQNDLEANVQ
FQQYLADLHEAETWIREKEPIVDNTNYGADEEAAGALLKKHEAFLLDLNSFGDSMKALRN
QANACQQQQAAPVEGVAGEQRVMALYDFQARSPREVTMKKGDVLTLLSSINKDWWKVEAA
DHQGIVPAVYVRRLAHDEFPMLPQRRREEPGNITQRQEQIENQYRSLLDRAEERRRRLLQ
RYNEFLLAYEAGDMLEWIQEKKAENTGVELDDVWELQKKFDEFQKDLNTNEPRLRDINKV
ADDLLFEGLLTPEGAQIRQELNSRWGSLQRLADEQRQLLGSAHAVEVFHREADDTKEQIE
KKCQALSAADPGSDLFSVQALQRRHEGFERDLVPLGDKVTILGETAERLSESHPDATEDL
QRQKMELNEAWEDLQGRTKDRKESLNEAQKFYLFLSKARDLQNWISSIGGMVSSQELAED
LTGIEILLERHQEHRADMEAEAPTFQALEDFSAELIDSGHHASPEIEKKLQAVKLERDDL
EKAWEKRKKILDQCLELQMFQGNCDQVESWMVARENSLRSDDKSSLDSLEALMKKRDDLD
KAITAQEGKITDLEHFAESLIADEHYAKEEIATRLQRVLDRWKALKAQLIDERTKLGDYA
NLKQFYRDLEELEEWISEMLPTACDESYKDATNIQRKYLKHQTFAHEVDGRSEQVHGVIN
LGNSLIECSACDGNEEAMKEQLEQLKEHWDHLLERTNDKGKKLNEASRQQRFNTSIRDFE
FWLSEAETLLAMKDQARDLASAGNLLKKHQLLEREMLAREDALKDLNTLAEDLLSSGTFN
VDQIVKKKDNVNKRFLNVQELAAAHHEKLKEAYALFQFFQDLDDEESWIEEKLIRVSSQD
YGRDLQGVQNLLKKHKRLEGELVAHEPAIQNVLDMAEKLKDKAAVGQEEIQLRLAQFVEH
WEKLKELAKARGLKLEESLEYLQFMQNAEEEEAWINEKNALAVRGDCGDTLAATQSLLMK
HEALENDFAVHETRVQNVCAQGEDILNKVLQEESQNKEISSKIEALNEKTPSLAKAIAAW
KLQLEDDYAFQEFNWKADVVEAWIADKETSLKTNGNGADLGDFLTLLAKQDTLDASLQSF
QQERLPEITDLKDKLISAQHNQSKAIEERYAALLKRWEQLLEASAVHRQKLLEKQLPLQK
AEDLFVEFAHKASALNNWCEKMEENLSEPVHCVSLNEIRQLQKDHEDFLASLARAQADFK
CLLELDQQIKALGVPSSPYTWLTVEVLERTWKHLSDIIEEREQELQKEEARQVKNFEMCQ
EFEQNASTFLQWILETRAYFLDGSLLKETGTLESQLEANKRKQKEIQAMKRQLTKIVDLG
DNLEDALILDIKYSTIGLAQQWDQLYQLGLRMQHNLEQQIQAKDIKGVSEETLKEFSTIY
KHFDENLTGRLTHKEFRSCLRGLNYYLPMVEEDEHEPKFEKFLDAVDPGRKGYVSLEDYT
AFLIDKESENIKSSDEIENAFQALAEGKSYITKEDMKQALTPEQVSFCATHMQQYMDPRG
RSHLSGYDYVGFTNSYFGN
NT seq
7260 nt
NT seq
+upstream
nt +downstream
nt
atggagcaatttccaaaggaaaccgttgtggagagcagtgggccaaaggttttggaaaca
gcagaagagatccaggagaggcgtcaggaagtgttgactcggtatcaaagtttcaaggag
cgggtcgctgagaggggtcagaagcttgaggattcctatcacttacaagttttcaagcga
gatgcagatgatctggggaagtggatcatggagaaagtcaatatcttaaccgataagagc
tatgaagacccaactaatatacaggggaaatatcagaagcatcaatcccttgaagcagag
gtgcaaacaaaatcaagactcatgtctgaactggaaaaaacaagggaagaacgatttacc
atgggtcattctgcccacgaagaaacgaaggcccatatagaggagctacgccacctgtgg
gacctgctgttagagctgaccctggagaagggtgaccagttgctgcgggccctgaagttc
cagcagtatgtacaggagtgtgctgacatcttagagtggattggagacaaggaggctata
gcgacatcagtggagctaggtgaagactgggagcgcaccgaagttctgcataagaaattt
gaagacttccaagtggagctggtagctaaagaagggagagttgttgaagtgaaccaatat
gccaatgagtgtgccgaggaaaaccatcctgacctacccttaattcagtctaagcaaaat
gaggtgaatgctgcctgggagcgccttcgtggtttggctctccagagacagaaagctctg
tccaatgctgcaaacttacaacgattcaaaagggatgtgactgaagccatccagtggatc
aaggagaaggaacctgtactcacctctgaggactatggcaaagaccttgttgcctctgaa
ggactgtttcacagtcacaagggacttgagagaaatcttgctgtcatgagtgacaaggtg
aaggagttatgtgctaaagcagagaagctgacactttcccatccttcagatgcacctcag
atccaggagatgaaagaagatctggtctccagctgggagcatattcgtgccctggccacc
agcagatatgaaaaactgcaggctacttattggtaccatcgattttcatctgactttgat
gaactctcaggctggatgaacgagaagactgctgcgatcaatgctgatgagctgccaaca
gatgtggctggtggagaagttctgctggacaggcatcagcagcataagcatgagattgac
tcttacgatgaccgatttcaatctgctgatgagactggtcaagacctcgtgaatgccaat
catgaagcctctgatgaagttcgggaaaagatggaaatacttgacaacaactggactgcc
ctgctggaactgtgggacgagcgtcatcgtcagtatgagcagtgcttggactttcatctc
ttctacagagacagtgagcaagtggacagttggatgagtagacaagaggccttcctggaa
aacgaggatctgggaaactcactgggcagtgcagaagcccttcttcagaagcatgaagac
tttgaggaagcctttactgcccaggaagagaagatcataactgtagacaagactgcaacc
aaattgattggtgatgaccattatgattcagagaacatcaaggctatccgtgacgggctg
ttagcccggcgggatgccctacgtgaaaaggctgccactagacgtagattgctgaaggag
tcattgcttctgcaaaaactgtatgaggactcagatgacctaaagaactggatcaacaag
aagaaaaagttggcagatgatgaagattacaaggacatacagaacttgaagagcagggtt
caaaagcagcaagtctttgaaaaggagttggcagttaataagacccagctggaaaacata
cagaaaactggccaagagatgattgagggtggtcactatgcctctgacaatgtgaccact
cgtctgagtgaagttgccagcctctgggaggagttgctggaggctacaaaacagaaaggg
acccagttgcatgaggccaaccagcagctgcaatttgaaaataatgcagaagatttgcag
cgctggctggaggatgttgagtggcaagtcacctctgaggattatgggaaaggcctggcc
gaggtacagaatcgactcaggaaacacggcctcctggagtcggctgtggctgctcgtcag
gatcaggtggatatccttacagacctggctgcatattttgaagaaataggccatcctgat
tctaaggatataagggcaaggcaagagtccttggtatgccgatttgaagctctgaaagag
ccactggccacccgaaagaagaagctcttagaccttctccatctgcagctgatttgtaga
gacacagaggatgaggaggcctggatccaagagactgaaccctcagctacttccacctac
cttggaaaggacctgattgcttccaaaaagcttctgaataggcatagagtcatcctggag
aacattgccagccatgaaccacgcattcaagagataacagaaaggggaaacaaaatggta
gaggaaggacactttgctgcagaagatgtggcctctagggtcaagagtttgaaccagaat
atggagtctctccgtgctcgagctgctaggcgacaaaatgatcttgaagccaatgtccag
ttccagcagtacctggctgacctgcatgaagcagaaacatggatcagagagaaggaacct
attgtagataatactaactatggtgctgatgaagaagcagctggggctcttctaaagaag
catgaggcctttctattagatctcaattcatttggagacagtatgaaagctctgcggaat
caggcaaacgcctgccagcaacaacaggctgcaccagtggagggagttgctggagaacaa
agggtcatggctttatatgacttccaggcccgcagcccccgagaagtcaccatgaagaaa
ggtgatgtcttaacgctgctcagttccatcaataaggactggtggaaggtggaagctgct
gatcatcagggcattgtcccagctgtctatgtcagaagactggcccacgatgagttcccg
atgctcccacagcggcgacgagaagagccaggaaacatcacccagcgccaggagcagatt
gagaaccaataccgctccctcttggatcgggcagaagaacgcagacgtcgtctattgcaa
cgttataatgaatttttattggcctatgaggcaggagacatgctggaatggattcaagag
aaaaaggcagaaaacactggagtggaactagatgatgtttgggagctgcagaaaaagttt
gatgagttccaaaaggatttgaataccaatgagcctcggctaagggatatcaacaaggta
gctgatgatctactatttgaaggacttctaacaccagaaggagctcaaatccggcaggaa
ttgaattcccgctggggttctttgcagaggcttgcagatgaacagcggcagctgctgggc
agtgcccatgctgttgaagtgtttcacagagaagcagatgacacgaaggagcagattgag
aagaaatgccaggccctcagtgctgcagaccctggctcagatctgttcagtgttcaggct
cttcagcgacggcatgagggctttgaaagggacctcgtacccctgggagataaggtgacc
atactgggggagacagcagagcggctcagtgagtcccatccagatgccactgaggacctg
cagagacagaaaatggagctgaatgaggcctgggaagacctgcaggggcgtacaaaggat
cgtaaggagagcctaaatgaggcccagaaattctacctgttcctcagcaaggccagggat
ctgcagaactggatcagtagcattggtggcatggtatcatcacaggagctggccgaagac
ttaactggcatagagatcttgctggagagacatcaggagcaccgtgctgacatggaggca
gaggctcccaccttccaggccttagaggacttcagtgcagaacttatcgacagtgggcac
catgctagccctgaaattgaaaaaaagcttcaagctgtcaagctagagagagatgatttg
gagaaggcttgggaaaaacgcaagaagatcctagaccagtgcctggagttgcagatgttc
caggggaactgtgatcaagttgagagctggatggtggcacgtgagaattccctgaggtca
gatgacaaaagttccttagacagtctggaggctttgatgaagaaacgggacgatttggac
aaagcaatcactgcccaggaagggaagatcactgacctagaacattttgctgagagcctc
attgctgatgaacactatgccaaagaagagattgctacgcggctccaacgtgtactagac
aggtggaaggctctcaaagcacaactgattgatgagcggacaaagcttggagactatgcc
aacctaaaacaattctaccgagaccttgaggagctggaagaatggatcagtgagatgctg
cccacagcctgtgatgaatcctacaaagacgccactaacattcagaggaaatacctgaaa
caccagacctttgcacatgaagtcgatggccgatctgagcaggtgcatggcgtcatcaac
ctggggaactccctgattgagtgtagcgcttgtgatggcaatgaagaggccatgaaggag
caactggaacagctgaaggaacattgggatcatctgcttgagagaacaaatgacaaaggg
aagaagctcaatgaggccagtcgtcaacagaggttcaacacaagcatccgggactttgag
ttctggctctcagaggcagagacattgctggccatgaaagatcaggccagggacttggct
tcagcaggaaacctactcaagaagcatcagctattggagagagagatgttggctcgagag
gatgcactcaaggacctgaatacattggctgaagatttgctctccagcgggactttcaac
gttgatcagattgtgaagaaaaaagataatgtcaacaagcgtttcctgaatgtccaagaa
ttggcagctgcacaccacgaaaaattgaaagaggcctatgccttgttccagttcttccag
gatctagatgatgaggaatcctggatagaggagaagttgatacgagtgagctcccaggac
tatgggagagatcttcagggggttcagaacttgctgaagaagcacaaacgcctagagggg
gagctggtggcccatgagcctgccatccagaatgtgctggatatggcagagaagctgaaa
gacaaggctgctgtggggcaagaggagatccagttgcggctggctcagtttgttgaacac
tgggagaagctcaaagagttggccaaggcccgaggacttaagttggaagaatccctagaa
tacttgcaattcatgcagaatgctgaggaagaggaagcttggatcaatgaaaagaatgct
ttggctgtccgaggagattgtggagatacattagctgctactcagagcttgctaatgaag
catgaagctttggaaaatgactttgctgtccatgagacccgagtacaaaatgtgtgtgca
caaggagaagacatcctaaataaggtgttgcaggaggaaagtcagaacaaagagatttct
tccaagatagaggctctgaatgaaaagaccccttctctggctaaggcaatagctgcttgg
aagttgcaattggaagacgattatgcctttcaggaattcaactggaaggctgatgtggta
gaggcttggatagctgataaggaaacaagcctaaagaccaatggcaatggtgcagacctt
ggtgacttcctcactcttctggcaaaacaggacactctggatgccagtctgcagagtttc
cagcaagagagacttcccgagatcactgacctgaaggacaaactgatttctgctcaacac
aaccagtctaaagccattgaagagcgttatgccgctctgctgaagcgctgggaacagttg
ctggaagcctcggcagtccacagacagaaattgctggagaaacagctgcctctacagaag
gctgaggacctgttcgtggaatttgcacataaggcttcagctttgaacaactggtgtgaa
aagatggaagaaaacttgtcagagcctgtgcactgtgtctccctgaatgaaattcggcag
ctgcagaaagaccatgaggacttcttggcctccctggctagggctcaagcagactttaaa
tgtttgctggagctagaccagcagattaaggccttaggtgtgccttccagcccttatacc
tggttaacagtggaggtgctggaaaggacctggaagcacctatctgacatcattgaggaa
cgggagcaggagctgcaaaaggaagaggcaagacaggtcaagaactttgagatgtgtcag
gagtttgaacagaatgccagtaccttccttcaatggatcctggaaaccagggcttacttt
ctggatggatcattgctcaaagaaacaggaactctggaatctcagctggaagcaaataaa
agaaaacagaaggagatccaggcgatgaagcgtcaactaaccaagattgtggacctgggg
gacaacttggaagacgctctgatccttgatatcaaatacagcaccattggattggctcag
cagtgggaccagctctaccagcttgggttgcggatgcaacacaacctggagcaacagatc
caggccaaggacatcaaaggtgtgagtgaagagactctaaaggaatttagcacaatctat
aaacactttgatgagaatttgacagggcgcctgactcacaaagagttccggtcctgcctg
agaggactcaattactacttgcccatggtggaggaggatgaacatgagcccaagtttgag
aagttcctggatgctgtggatccagggaggaagggctatgtctcactggaggactatact
gctttcctgattgacaaggagtcagaaaacatcaagtccagtgatgaaatagagaatgcc
ttccaagccctggcagagggcaagtcatatattaccaaagaagacatgaagcaggccctt
accccagagcaagtgtcattctgtgccacacatatgcagcaatatatggacccacggggt
cgaagccatctctctggctatgactacgttggcttcaccaattcctactttggcaactaa
DBGET
integrated database retrieval system
