Homo sapiens (human): 6710
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Entry
6710 CDS
T01001
Symbol
SPTB, EL3, HS2, HSPTB1, SPH2
Name
(RefSeq) spectrin beta chain, erythrocytic isoform b
KO
K27409
spectrin beta, erythrocytic
Organism
hsa
Homo sapiens (human)
Disease
H00230
Hereditary spherocytosis
H00231
Hereditary elliptocytosis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
6710 (SPTB)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
Cross-linking proteins
6710 (SPTB)
Intermediate filaments
Intermediate filament-binding proteins
6710 (SPTB)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Spectrin
CH
CAMSAP_CH
CREPT
Tnp_22_trimer
Motif
Other DBs
NCBI-GeneID:
6710
NCBI-ProteinID:
NP_001342366
OMIM:
182870
HGNC:
11274
UniProt:
P11277
Structure
PDB
PDBj
LinkDB
All DBs
Position
14:complement(64746283..64879907)
Genome browser
AA seq
2137 aa
AA seq
DB search
MTSATEFENVGNQPPYSRINARWDAPDDELDNDNSSARLFERSRIKALADEREVVQKKTF
TKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEMLPKPTKGKMRIHCLENVDKAL
QFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEGRETRSAKDALL
LWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFNV
AERQLGIIPLLDPEDVFTENPDEKSIITYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIET
EKMIEKYSGLASDLLTWIEQTITVLNSRKFANSLTGVQQQLQAFSTYRTVEKPPKFQEKG
NLEVLLFTIQSRMRANNQKVYTPHDGKLVSDINRAWESLEEAEYRRELALRNELIRQEKL
EQLARRFDRKAAMRETWLSENQRLVAQDNFGYDLAAVEAAKKKHEAIETDTAAYEERVRA
LEDLAQELEKENYHDQKRITARKDNILRLWSYLQELLQSRRQRLETTLALQKLFQDMLHS
IDWMDEIKAHLLSAEFGKHLLEVEDLLQKHKLMEADIAIQGDKVKAITAATLKFTEGKGY
QPCDPQVIQDRISHLEQCFEELSNMAAGRKAQLEQSKRLWKFFWEMDEAESWIKEKEQIY
SSLDYGKDLTSVLILQRKHKAFEDELRGLDAHLEQIFQEAHGMVARKQFGHPQIEARIKE
VSAQWDQLKDLAAFCKKNLQDAENFFQFQGDADDLKAWLQDAHRLLSGEDVGQDEGATRA
LGKKHKDFLEELEESRGVMEHLEQQAQGFPEEFRDSPDVTHRLQALRELYQQVVAQADLR
QQRLQEALDLYTVFGETDACELWMGEKEKWLAEMEMPDTLEDLEVVQHRFDILDQEMKTL
MTQIDGVNLAANSLVESGHPRSREVKQYQDHLNTRWQAFQTLVSERREAVDSALRVHNYC
VDCEETSKWITDKTKVVESTKDLGRDLAGIIAIQRKLSGLERDVAAIQARVDALERESQQ
LMDSHPEQKEDIGQRQKHLEELWQGLQQSLQGQEDLLGEVSQLQAFLQDLDDFQAWLSIT
QKAVASEDMPESLPEAEQLLQQHAGIKDEIDGHQDSYQRVKESGEKVIQGQTDPEYLLLG
QRLEGLDTGWNALGRMWESRSHTLAQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSL
EAAEAGIRKFEDFLGSMENNRDKVLSPVDSGNKLVAEGNLYSDKIKEKVQLIEDRHRKNN
EKAQEASVLLRDNLELQNFLQNCQELTLWINDKLLTSQDVSYDEARNLHNKWLKHQAFVA
ELASHEGWLENIDAEGKQLMDEKPQFTALVSQKLEALHRLWDELQATTKEKTQHLSAARS
SDLRLQTHADLNKWISAMEDQLRSDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFA
QVPSMGEEGGDADLSIEKRFLDLLEPLGRRKKQLESSRAKLQISRDLEDETLWVEERLPL
AQSADYGTNLQTVQLFMKKNQTLQNEILGHTPRVEDVLQRGQQLVEAAEIDCQDLEERLG
HLQSSWDRLREAAAGRLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAI
VMLKRHLRQQRAVEDYGRNIKQLASRAQGLLSAGHPEGEQIIRLQGQVDKHYAGLKDVAE
ERKRKLENMYHLFQLKRETDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARETG
AIGQERVDNVNAFIERLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDLH
RYFYTGAEILGLIDEKHRELPEDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVAT
RLQTAYAGEKAEAIQNKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFSMARDLLSWME
SIIRQIETQERPRDVSSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQHQASEEI
REKLQQVMSRRKEMNEKWEARWERLRMLLEVCQFSRDASVAEAWLIAQEPYLASGDFGHT
VDSVEKLIKRHEAFEKSTASWAERFAALEKPTTLELKERQIAERPAEETGPQEEEGETAG
EAPVSHHAATERTSPVSLWSRLSSSWESLQPEPSHPY
NT seq
6414 nt
NT seq
+upstream
nt +downstream
nt
atgacatcggccacagagtttgaaaatgtgggcaaccagccaccttacagcaggatcaat
gcccgctgggacgccccagacgacgagctggataatgacaacagctcagccaggctcttt
gagaggtcccggataaaggccttggcagatgagcgggaagttgttcagaaaaagaccttc
acgaaatgggtgaactcgcacctggctcgagtgtcctgccgcatcaccgatctctacaag
gacctgcgggatgggcgcatgctcatcaagctgctggaggtgctctctggagagatgctg
ccaaagcccaccaaggggaagatgcgcatccactgcctggagaatgtggacaaggctctc
cagttcctcaaggagcagcgtgtacacctggagaacatgggctcccacgacattgtagat
ggcaaccaccgcctggtcctgggcctcatctggaccatcatcctccgcttccagattcag
gacattgtggtccaaactcaggaaggtcgtgaaacacgctcagccaaggatgcgttgctg
ttgtggtgtcagatgaagacggcaggctaccctcatgttaatgtcaccaactttacctcc
agctggaaggatggcttggcctttaatgccctgatacacaagcaccggcccgacctgatc
gactttgataagctgaaggactccaatgcccggcacaacctggagcacgcattcaatgtg
gctgagcgccagctgggcatcatcccgctcctcgaccccgaagatgtctttacggaaaac
cctgatgagaaatccatcatcacctatgtggtggccttttaccactacttctccaagatg
aaggtgctggcagtggagggcaagcgtgtcggcaaggttattgaccatgccattgagact
gagaagatgattgaaaagtacagcgggctagcctcggacctgctcacctggatcgagcag
accatcactgtcctgaacagccgcaagtttgccaactcgctgacgggcgtccagcagcag
ctgcaggccttcagcacctaccgcaccgtggagaagccgcccaagtttcaagagaagggg
aatctggaagttctactttttaccatccagtcccggatgagagccaacaatcagaaagtg
tacacaccccacgatgggaaactagtgtctgacatcaacagggcctgggaaagcctggag
gaagctgagtatcggcgggagctggccctgagaaatgagctcattcggcaggagaagcta
gagcaactggcccggcgctttgaccggaaggccgcaatgagagagacctggctcagtgaa
aaccagcgcctcgtggcccaggataactttgggtatgacctggcagctgtggaggccgcc
aagaagaagcatgaggccatcgagaccgacacggctgcctacgaggagcgggtgagagcc
ctggaggacctggctcaggagctggagaaagagaactaccatgaccagaagcgcatcacg
gcccgcaaggacaatatactgcgcctatggagctacctgcaggagctgctgcagtcccgg
cgccagaggctcgagaccaccctggcactgcagaagctcttccaggacatgctgcacagc
atcgactggatggatgagatcaaggctcacctcttgtctgccgagtttgggaagcacttg
ttggaggttgaagacctgctacagaagcacaagttgatggaagctgacatcgccatccaa
ggggacaaagtgaaggccatcaccgcagccaccctgaagttcaccgaggggaaagggtac
cagccttgtgacccccaggtcatccaggaccgcatcagccacttggagcagtgctttgag
gagctgagcaacatggcagctgggcggaaggcccaactggagcagtccaaacgactctgg
aagttcttctgggagatggatgaggctgagagctggatcaaggagaaggagcagatctat
tcttccctggactatggcaaagacctgaccagtgtgctcatcttacagcgcaagcacaag
gcctttgaggatgagctccgtgggctggatgctcacctggagcagatcttccaggaggct
catggcatggttgcgcgcaagcagtttgggcacccgcagatcgaggcccgcataaaggag
gtgtcggcacagtgggaccagctgaaggacctggctgccttctgcaagaagaacctccag
gatgctgagaactttttccagttccagggcgatgcggatgacctgaaggcttggctgcaa
gacgcccaccggctgctctctggtgaagatgtggggcaggacgaaggggccacgcgggcc
ctggggaaaaagcacaaggacttcctggaggagctggaggagagccgtggggtgatggag
cacctggagcagcaggcccagggattccccgaagagtttcgggattccccagatgtgacc
catcggctgcaggccctgcgggagctctaccaacaggtggtggcccaggcggacctgcgt
cagcagaggctgcaggaagccctggacctgtacacggtgttcggggagacagacgcctgt
gagctgtggatgggagagaaggagaagtggctggccgagatggaaatgccagacaccctg
gaggacctggaggtcgtgcagcacaggttcgacatcctggaccaggagatgaagaccttg
atgactcagattgatggtgtgaacctcgctgccaacagcttggtagagagtggccaccca
cgcagcagggaggtgaagcagtaccaggaccatctgaacaccaggtggcaggcatttcag
accctggtgtcggagcggcgggaggctgtggactcagccctccgagtgcacaactactgc
gtagattgcgaggagaccagcaagtggatcacggacaagacaaaggtagtggagtccaca
aaagacctggggcgggacctggcaggtatcatcgccatccagaggaagttgtcagggctg
gagcgtgacgtggccgccatccaggcccgtgtggatgccctggagcgtgagtcccagcag
ctgatggactcgcaccctgagcagaaggaggatattggtcagcggcaaaaacacttggag
gagctgtggcagggcctgcagcaatccctgcagggccaggaggacttgctgggggaagtc
agccagctgcaggccttcctgcaggatctggatgacttccaggcctggctctccatcacc
cagaaggctgtggcctctgaggacatgcccgaatccctcccagaggctgagcagctcctg
cagcagcatgcaggtatcaaggatgagattgacgggcaccaagacagctaccagcgtgtt
aaggagtctggggagaaagtgatccaaggccagacggacccagagtatctgcttctgggc
cagcggctggagggcctggatactggctggaatgccctgggcaggatgtgggagagccgc
agccacaccctcgctcagtgccttggcttccaggagttccagaaagatgccaagcaggct
gaagccatcctcagcaaccaggaatacactctggctcacttggagcccccagactccctg
gaagctgcagaggctgggatccggaagtttgaggatttcttggggtctatggagaacaac
cgggataaggtcttgagtcctgtggactctggaaacaagctggtagctgagggaaaccta
tactcagacaagatcaaggagaaggtgcagctgattgaggacaggcacaggaagaacaac
gagaaggcccaggaggcctctgtcctactgagagacaacctggagctacagaacttcctc
cagaactgccaggagctcactctctggatcaacgacaagctgctgacatctcaggatgtc
tcctatgatgaagcacgaaaccttcacaataaatggctaaagcaccaggcgtttgtggca
gagctggcttcccatgaagggtggctagagaacatcgatgcggaaggaaagcagctgatg
gatgagaagccccagtttacagccctggtgtcccaaaagctggaagccctgcaccggctc
tgggacgagctgcaggccaccacaaaggagaagacccagcacctctcggctgccaggagc
tccgacctgcgcttgcagacccatgctgacctcaacaagtggatcagcgccatggaggac
cagctgcggtcagacgacccgggcaaggacctgaccagtgtcaatcggatgttggctaag
ctgaagcgagtggaggaccaagtgaatgtgcgaaaagaggagctgggggagctgtttgcc
caggtgccttcaatgggagaggagggaggagatgcagacttgagcatcgagaagcggttc
ctggacctcctggaacccctaggaaggaggaagaagcagctggaatcatccagagccaag
ctgcagatcagccgggacttagaggatgagacgctttgggtggaggagaggctgcctctg
gcccagtcagccgactatggcactaatctgcaaactgtgcaactgttcatgaagaagaac
cagacactgcagaatgagattctgggccatacgccgcgggttgaggatgtgctgcagaga
gggcagcagctggtggaggcggcggagatcgactgccaggaccttgaggagcgcctgggg
cacctgcagagctcctgggacaggctgcgggaggcagcggccgggaggctgcagcgactg
agggacgccaacgaggcacagcagtactacctggatgcagacgaggctgaggcctggatt
ggcgagcaggagctctacgtcatctccgatgagatccccaaggatgaagagggcgccatt
gtgatgctgaagcgacatttgcggcagcagcgtgcggtggaggactacggccggaacatc
aagcagctggccagccgggcccagggcctgctgtctgcaggccaccctgagggggaacag
atcatcagacttcaggggcaagtggacaagcactacgcagggctgaaggacgtggcggaa
gagcgcaagcgcaagctggagaacatgtaccacctgttccagctcaagcgggagaccgac
gacctggagcagtggatttcagaaaaggagctagtggcctcttccccggaaatggggcaa
gactttgaccacgtgactcttctgcgggacaagttccgggactttgcccgggagaccggg
gcgattgggcaggagcgggtggacaatgtgaatgccttcatcgagcgactcatcgacgcg
ggccacagcgaggcggccaccatcgccgagtggaaggacgggctgaacgagatgtgggca
gacctcctggagctcattgacacgcgcatgcagctgctggccgcctcctatgacctgcac
cgctacttctacacgggtgccgagatcctgggcctcatcgacgagaagcaccgcgagctg
cccgaggacgtggggctggacgccagcacggccgagtccttccaccgggtgcacacagcc
ttcgagcgggagctccacctgctgggtgtccaggtgcagcagttccaggacgtggccacc
cgtctgcagacagcatatgctggggagaaggcagaggccatccagaacaaggagcaggag
gtgtctgccgcgtggcaggcgctgctcgatgcctgtgccgggcgccggacccagctagtg
gacacggcggataaattccgcttcttcagcatggcccgtgacctcctctcctggatggag
agcatcatccggcagatcgagacccaggagaggcccagggatgtctcctctgtggaactg
ctcatgaagtatcaccagggcatcaatgcagagattgaaacccggagcaagaacttcagt
gcctgcctggagcttggcgagtccctgctgcagcggcagcaccaggcctcagaggagatc
cgcgagaaactgcagcaggtgatgtccaggaggaaagagatgaatgagaagtgggaagcc
cgctgggagcggctccgcatgttgctggaggtgtgccagttctcgagggatgcctctgtg
gctgaggcgtggctgattgcccaggagccctacctggccagcggggactttggacacaca
gtggacagtgtggagaagctcatcaagaggcatgaggcttttgagaagtccacggccagc
tgggcagagcgctttgctgccctggagaagcccaccacgcttgagctgaaagaacgccag
attgcagagagacccgcagaggagactgggcctcaagaggaggaaggcgagacagcaggg
gaggctccagtttcccaccatgcggccaccgagagaacgtccccggtcagtctctggtct
cgtttgtctagttcctgggagtcactgcagccagagccctctcacccctactag
DBGET
integrated database retrieval system
