Homo sapiens (human): 6720
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Entry
6720 CDS
T01001
Symbol
SREBF1, HMD, IFAP2, SREBP1, bHLHd1
Name
(RefSeq) sterol regulatory element-binding protein 1 isoform 2
KO
K07197
sterol regulatory element-binding transcription factor 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04152
AMPK signaling pathway
hsa04910
Insulin signaling pathway
hsa04931
Insulin resistance
hsa04932
Non-alcoholic fatty liver disease
hsa04936
Alcoholic liver disease
Disease
H00740
Ichthyosis follicularis, alopecia, and photophobia syndrome
H02944
Hereditary mucoepithelial dysplasia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
6720 (SREBF1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
6720 (SREBF1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
6720 (SREBF1)
04932 Non-alcoholic fatty liver disease
6720 (SREBF1)
04931 Insulin resistance
6720 (SREBF1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
6720 (SREBF1)
04131 Membrane trafficking [BR:
hsa04131
]
6720 (SREBF1)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
Ubiquitous bHLH-ZIP factors
6720 (SREBF1)
Membrane trafficking [BR:
hsa04131
]
Endoplasmic reticulum (ER) - Golgi transport
Others
Others
6720 (SREBF1)
Autophagy
Mitophagy
Other mitophagy associated proteins
6720 (SREBF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HLH
bHLH_IRO3
Motif
Other DBs
NCBI-GeneID:
6720
NCBI-ProteinID:
NP_004167
OMIM:
184756
HGNC:
11289
Ensembl:
ENSP00000261646.5
UniProt:
P36956
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:complement(17811334..17836986)
Genome browser
AA seq
1147 aa
AA seq
DB search
MDEPPFSEAALEQALGEPCDLDAALLTDIEDMLQLINNQDSDFPGLFDPPYAGSGAGGTD
PASPDTSSPGSLSPPPATLSSSLEAFLSGPQAAPSPLSPPQPAPTPLKMYPSMPAFSPGP
GIKEESVPLSILQTPTPQPLPGALLPQSFPAPAPPQFSSTPVLGYPSPPGGFSTGSPPGN
TQQPLPGLPLASPPGVPPVSLHTQVQSVVPQQLLTVTAAPTAAPVTTTVTSQIQQVPVLL
QPHFIKADSLLLTAMKTDGATVKAAGLSPLVSGTTVQTGPLPTLVSGGTILATVPLVVDA
EKLPINRLAAGSKAPASAQSRGEKRTAHNAIEKRYRSSINDKIIELKDLVVGTEAKLNKS
AVLRKAIDYIRFLQHSNQKLKQENLSLRTAVHKSKSLKDLVSACGSGGNTDVLMEGVKTE
VEDTLTPPPSDAGSPFQSSPLSLGSRGSGSGGSGSDSEPDSPVFEDSKAKPEQRPSLHSR
GMLDRSRLALCTLVFLCLSCNPLASLLGARGLPSPSDTTSVYHSPGRNVLGTESRDGPGW
AQWLLPPVVWLLNGLLVLVSLVLLFVYGEPVTRPHSGPAVYFWRHRKQADLDLARGDFAQ
AAQQLWLALRALGRPLPTSHLDLACSLLWNLIRHLLQRLWVGRWLAGRAGGLQQDCALRV
DASASARDAALVYHKLHQLHTMGKHTGGHLTATNLALSALNLAECAGDAVSVATLAEIYV
AAALRVKTSLPRALHFLTRFFLSSARQACLAQSGSVPPAMQWLCHPVGHRFFVDGDWSVL
STPWESLYSLAGNPVDPLAQVTQLFREHLLERALNCVTQPNPSPGSADGDKEFSDALGYL
QLLNSCSDAAGAPAYSFSISSSMATTTGVDPVAKWWASLTAVVIHWLRRDEEAAERLCPL
VEHLPRVLQESERPLPRAALHSFKAARALLGCAKAESGPASLTICEKASGYLQDSLATTP
ASSSIDKAVQLFLCDLLLVVRTSLWRQQQPPAPAPAAQGTSSRPQASALELRGFQRDLSS
LRRLAQSFRPAMRRVFLHEATARLMAGASPTRTHQLLDRSLRRRAGPGGKGGAVAELEPR
PTRREHAEALLLASCYLPPGFLSAPGQRVGMLAEAARTLEKLGDRRLLHDCQQMLMRLGG
GTTVTSS
NT seq
3444 nt
NT seq
+upstream
nt +downstream
nt
atggacgagccacccttcagcgaggcggctttggagcaggcgctgggcgagccgtgcgat
ctggacgcggcgctgctgaccgacatcgaagacatgcttcagcttatcaacaaccaagac
agtgacttccctggcctatttgacccaccctatgctgggagtggggcagggggcacagac
cctgccagccccgataccagctccccaggcagcttgtctccacctcctgccacattgagc
tcctctcttgaagccttcctgagcgggccgcaggcagcgccctcacccctgtcccctccc
cagcctgcacccactccattgaagatgtacccgtccatgcccgctttctcccctgggcct
ggtatcaaggaagagtcagtgccactgagcatcctgcagacccccaccccacagcccctg
ccaggggccctcctgccacagagcttcccagccccagccccaccgcagttcagctccacc
cctgtgttaggctaccccagccctccgggaggcttctctacaggaagccctcccgggaac
acccagcagccgctgcctggcctgccactggcttccccgccaggggtcccgcccgtctcc
ttgcacacccaggtccagagtgtggtcccccagcagctactgacagtcacagctgccccc
acggcagcccctgtaacgaccactgtgacctcgcagatccagcaggtcccggtcctgctg
cagccccacttcatcaaggcagactcgctgcttctgacagccatgaagacagacggagcc
actgtgaaggcggcaggtctcagtcccctggtctctggcaccactgtgcagacagggcct
ttgccgaccctggtgagtggcggaaccatcttggcaacagtcccactggtcgtagatgcg
gagaagctgcctatcaaccggctcgcagctggcagcaaggccccggcctctgcccagagc
cgtggagagaagcgcacagcccacaacgccattgagaagcgctaccgctcctccatcaat
gacaaaatcattgagctcaaggatctggtggtgggcactgaggcaaagctgaataaatct
gctgtcttgcgcaaggccatcgactacattcgctttctgcaacacagcaaccagaaactc
aagcaggagaacctaagtctgcgcactgctgtccacaaaagcaaatctctgaaggatctg
gtgtcggcctgtggcagtggagggaacacagacgtgctcatggagggcgtgaagactgag
gtggaggacacactgaccccacccccctcggatgctggctcacctttccagagcagcccc
ttgtcccttggcagcaggggcagtggcagcggtggcagtggcagtgactcggagcctgac
agcccagtctttgaggacagcaaggcaaagccagagcagcggccgtctctgcacagccgg
ggcatgctggaccgctcccgcctggccctgtgcacgctcgtcttcctctgcctgtcctgc
aaccccttggcctccttgctgggggcccgggggcttcccagcccctcagataccaccagc
gtctaccatagccctgggcgcaacgtgctgggcaccgagagcagagatggccctggctgg
gcccagtggctgctgcccccagtggtctggctgctcaatgggctgttggtgctcgtctcc
ttggtgcttctctttgtctacggtgagccagtcacacggccccactcaggccccgccgtg
tacttctggaggcatcgcaagcaggctgacctggacctggcccggggagactttgcccag
gctgcccagcagctgtggctggccctgcgggcactgggccggcccctgcccacctcccac
ctggacctggcttgtagcctcctctggaacctcatccgtcacctgctgcagcgtctctgg
gtgggccgctggctggcaggccgggcagggggcctgcagcaggactgtgctctgcgagtg
gatgctagcgccagcgcccgagacgcagccctggtctaccataagctgcaccagctgcac
accatggggaagcacacaggcgggcacctcactgccaccaacctggcgctgagtgccctg
aacctggcagagtgtgcaggggatgccgtgtctgtggcgacgctggccgagatctatgtg
gcggctgcattgagagtgaagaccagtctcccacgggccttgcattttctgacacgcttc
ttcctgagcagtgcccgccaggcctgcctggcacagagtggctcagtgcctcctgccatg
cagtggctctgccaccccgtgggccaccgtttcttcgtggatggggactggtccgtgctc
agtaccccatgggagagcctgtacagcttggccgggaacccagtggaccccctggcccag
gtgactcagctattccgggaacatctcttagagcgagcactgaactgtgtgacccagccc
aaccccagccctgggtcagctgatggggacaaggaattctcggatgccctcgggtacctg
cagctgctgaacagctgttctgatgctgcgggggctcctgcctacagcttctccatcagt
tccagcatggccaccaccaccggcgtagacccggtggccaagtggtgggcctctctgaca
gctgtggtgatccactggctgcggcgggatgaggaggcggctgagcggctgtgcccgctg
gtggagcacctgccccgggtgctgcaggagtctgagagacccctgcccagggcagctctg
cactccttcaaggctgcccgggccctgctgggctgtgccaaggcagagtctggtccagcc
agcctgaccatctgtgagaaggccagtgggtacctgcaggacagcctggctaccacacca
gccagcagctccattgacaaggccgtgcagctgttcctgtgtgacctgcttcttgtggtg
cgcaccagcctgtggcggcagcagcagcccccggccccggccccagcagcccagggcacc
agcagcaggccccaggcttccgcccttgagctgcgtggcttccaacgggacctgagcagc
ctgaggcggctggcacagagcttccggcccgccatgcggagggtgttcctacatgaggcc
acggcccggctgatggcgggggccagccccacacggacacaccagctcctcgaccgcagt
ctgaggcggcgggcaggccccggtggcaaaggaggcgcggtggcggagctggagccgcgg
cccacgcggcgggagcacgcggaggccttgctgctggcctcctgctacctgccccccggc
ttcctgtcggcgcccgggcagcgcgtgggcatgctggctgaggcggcgcgcacactcgag
aagcttggcgatcgccggctgctgcacgactgtcagcagatgctcatgcgcctgggcggt
gggaccactgtcacttccagctag
DBGET
integrated database retrieval system
