Homo sapiens (human): 6721
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Entry
6721 CDS
T01001
Symbol
SREBF2, SREBP-2, SREBP2, bHLHd2
Name
(RefSeq) sterol regulatory element binding transcription factor 2
KO
K09107
sterol regulatory element-binding transcription factor 2
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
6721 (SREBF2)
04131 Membrane trafficking [BR:
hsa04131
]
6721 (SREBF2)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
Ubiquitous bHLH-ZIP factors
6721 (SREBF2)
Membrane trafficking [BR:
hsa04131
]
Endoplasmic reticulum (ER) - Golgi transport
Others
Others
6721 (SREBF2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HLH
KH_DTX3L
Motif
Other DBs
NCBI-GeneID:
6721
NCBI-ProteinID:
NP_004590
OMIM:
600481
HGNC:
11290
Ensembl:
ENSG00000198911
UniProt:
Q12772
Structure
PDB
PDBj
LinkDB
All DBs
Position
22:41833105..41907305
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AA seq
1141 aa
AA seq
DB search
MDDSGELGGLETMETLTELGDELTLGDIDEMLQFVSNQVGEFPDLFSEQLCSSFPGSGGS
GSSSGSSGSSSSSSNGRGSSSGAVDPSVQRSFTQVTLPSFSPSAASPQAPTLQVKVSPTS
VPTTPRATPILQPRPQPQPQPQTQLQQQTVMITPTFSTTPQTRIIQQPLIYQNAATSFQV
LQPQVQSLVTSSQVQPVTIQQQVQTVQAQRVLTQTANGTLQTLAPATVQTVAAPQVQQVP
VLVQPQIIKTDSLVLTTLKTDGSPVMAAVQNPALTALTTPIQTAALQVPTLVGSSGTILT
TMPVMMGQEKVPIKQVPGGVKQLEPPKEGERRTTHNIIEKRYRSSINDKIIELKDLVMGT
DAKMHKSGVLRKAIDYIKYLQQVNHKLRQENMVLKLANQKNKLLKGIDLGSLVDNEVDLK
IEDFNQNVLLMSPPASDSGSQAGFSPYSIDSEPGSPLLDDAKVKDEPDSPPVALGMVDRS
RILLCVLTFLCLSFNPLTSLLQWGGAHDSDQHPHSGSGRSVLSFESGSGGWFDWMMPTLL
LWLVNGVIVLSVFVKLLVHGEPVIRPHSRSSVTFWRHRKQADLDLARGDFAAAAGNLQTC
LAVLGRALPTSRLDLACSLSWNVIRYSLQKLRLVRWLLKKVFQCRRATPATEAGFEDEAK
TSARDAALAYHRLHQLHITGKLPAGSACSDVHMALCAVNLAECAEEKIPPSTLVEIHLTA
AMGLKTRCGGKLGFLASYFLSRAQSLCGPEHSAVPDSLRWLCHPLGQKFFMERSWSVKSA
AKESLYCAQRNPADPIAQVHQAFCKNLLERAIESLVKPQAKKKAGDQEEESCEFSSALEY
LKLLHSFVDSVGVMSPPLSRSSVLKSALGPDIICRWWTSAITVAISWLQGDDAAVRSHFT
KVERIPKALEVTESPLVKAIFHACRAMHASLPGKADGQQSSFCHCERASGHLWSSLNVSG
ATSDPALNHVVQLLTCDLLLSLRTALWQKQASASQAVGETYHASGAELAGFQRDLGSLRR
LAHSFRPAYRKVFLHEATVRLMAGASPTRTHQLLEHSLRRRTTQSTKHGEVDAWPGQRER
ATAILLACRHLPLSFLSSPGQRAVLLAEAARTLEKVGDRRSCNDCQQMIVKLGGGTAIAA
S
NT seq
3426 nt
NT seq
+upstream
nt +downstream
nt
atggacgacagcggcgagctgggtggtctggagaccatggagaccctcacggagctgggc
gacgagctgaccctgggagacatcgacgagatgctgcaatttgtcagtaatcaagtggga
gagttccctgacttgttttcagaacagctgtgtagctcctttcctggcagtggtggtagt
ggtagcagcagcggcagcagtggcagcagcagcagcagcagcaatggcaggggcagcagc
agcggagctgtggacccttcagtgcaacggtcattcacccaggtcacattaccttccttc
tctccctcggcggcctccccacaggctccaactctgcaagtcaaggtttctcccacctca
gttcccaccacacccagggcaactcctattcttcagccccgcccccagccccagcctcaa
cctcaaactcagctgcaacaacagacggtaatgatcacgccaacattcagcaccactccg
cagacgaggatcatccagcagcctttgatataccagaatgcagctactagctttcaagtc
cttcagcctcaagtccaaagcctggtgacatcctcccaggtacagccggtcaccattcag
cagcaggtgcagacagtacaggcccagcgggtgctgacacaaacggccaatggcacgctg
cagacccttgccccggctacggtgcagacagttgctgcgccacaggtgcagcaggtcccg
gtcctggtccagcctcagatcatcaagacagattcccttgttttgaccacactgaagaca
gatggcagccctgttatggctgcggtccagaacccggccctcaccgccctcaccacccct
atccagacggctgcccttcaagtaccaaccctggtgggcagcagtgggaccattctgacc
acaatgcctgtaatgatggggcaagagaaagtgcccattaagcaggtacctgggggagtc
aagcagcttgagccccccaaagaaggagaaaggcggacaacccataatatcattgagaaa
cgatatcgctcctccatcaatgacaaaatcatcgaattgaaagacctggtcatggggaca
gacgccaagatgcacaagtctggcgttctgaggaaggccattgattacatcaaatacttg
cagcaggtcaatcataaactgcgccaggagaacatggtgctgaagctggcaaatcaaaag
aacaagcttctaaagggcatcgacctaggcagtctggtggacaatgaggtggacctgaag
atcgaggactttaatcagaatgtccttctgatgtcccccccagcctctgactcagggtcc
caggctggcttctctccctactccattgactctgagccaggaagccctctattggatgat
gcaaaggtcaaagatgagccagactctcctcctgtggcgctgggcatggtagaccgctca
cggattcttctgtgtgtcctcaccttcctgtgcctctcctttaaccccctgacttccctg
ctgcagtggggaggggcccacgactctgaccagcacccacactcaggctctggccgcagt
gtcctgtcattcgagtcaggttctgggggctggtttgactggatgatgcctactcttctc
ttatggctggtaaatggtgtgattgtcctgagcgtctttgtgaagctgctggttcatggg
gagccagtgatccggccacactcgcgctcctcggtcaccttctggaggcaccggaaacag
gcagatctggatctcgccagaggagattttgcagctgctgccggcaacctacaaacctgc
ctggcagttttgggccgggcactgcccacctcccgcctggacctggcctgcagcctctcc
tggaacgtgatccgctacagcctgcagaagctacgcctggtgcgctggctgctcaagaaa
gtcttccagtgccggcgggccacgccagccactgaggcaggctttgaagacgaagctaag
accagcgcccgggatgcggctctggcctatcaccggctgcaccagctgcacatcacaggg
aagcttcctgcaggatccgcctgttccgatgtacacatggcgttgtgtgccgtgaacctg
gctgaatgtgcagaggagaagatcccaccgagcacactggttgagatccatctgactgct
gccatggggctcaagacccggtgtggaggcaagctgggcttcctggccagctacttcctc
agccgagcccagagcctgtgtggccccgagcacagtgctgttcctgactccctgcgctgg
ctctgccaccccctgggccagaagtttttcatggagcggagctggtctgtgaagtcagct
gccaaggagagtctatactgtgcccagaggaacccagctgaccccattgcgcaggtccac
caggccttctgcaagaacctgctggagcgagctatagagtccttggtgaaacctcaggcc
aagaagaaggctggagaccaggaagaagagagctgtgaattctccagtgctctggagtac
ttgaaattacttcattcttttgtggactctgtgggggttatgagccccccactctccagg
agctccgtgctcaagtccgccctgggtccagacatcatctgtcggtggtggacgtctgca
atcactgtggccatcagctggctccagggagacgatgcagctgtgcgctctcattttacc
aaagtggaacgcatccccaaggccctggaagtgacagagagccccctggtgaaggccatc
ttccatgcctgcagagccatgcatgcctcactccctgggaaagcagatgggcagcagagt
tccttctgccattgcgagagggccagtggccacctatggagcagcctcaacgtcagtggg
gccacctctgaccctgccctcaaccacgtggtccagctgctcacctgtgacctgctactg
tcgctacggacagcgctctggcaaaaacaggccagtgccagccaggctgtgggggagacc
taccacgcgtcaggcgctgaactggcgggcttccaacgggacctgggcagcctgcgcagg
ctggcacacagcttccgcccagcataccgcaaggtgttcctgcatgaagccaccgtgcgc
ctgatggcaggagccagccccacccgcacccaccagctgctggaacacagcctgcggcgg
cgcaccacgcagagcaccaagcacggagaggtggatgcctggcccggccagcgagagcgg
gccaccgccatcctgctggcctgccgccacctgcccctctccttcctctcctccccgggc
cagcgggcagtgctgctggccgaagctgcccgcaccctggagaaggtgggcgaccggcgc
tcctgcaacgactgccagcagatgattgttaagctgggtggtggcactgccattgccgcc
tcctga
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