KEGG   Homo sapiens (human): 6737
Entry
6737              CDS       T01001                                 
Symbol
TRIM21, RNF81, RO52, Ro/SSA, SSA, SSA1
Name
(RefSeq) tripartite motif containing 21
  KO
K10651  tripartite motif-containing protein 21 [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Pathway
hsa05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09163 Immune disease
   05322 Systemic lupus erythematosus
    6737 (TRIM21)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    6737 (TRIM21)
   04131 Membrane trafficking [BR:hsa04131]
    6737 (TRIM21)
   04121 Ubiquitin system [BR:hsa04121]
    6737 (TRIM21)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     6737 (TRIM21)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     6737 (TRIM21)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Other autophagy associated proteins
   TRIM-directed selective autophagy
    6737 (TRIM21)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRIM/RBCC proteins
    6737 (TRIM21)
SSDB
Motif
Pfam: SPRY PRY zf-C3HC4 zf-RING_UBOX zf-C3HC4_4 zf-C3HC4_2 zf-B_box zf-RING_2 zf-C3HC4_3 zf-RING_6 zf-RING_5 zf-Nse zf-RING_4 RING_XB3-XBAT31 zf-rbx1 zf-RING_10 Sina_RING U-box zf-UDP At2g31720-like zf-ANAPC11
Other DBs
NCBI-GeneID: 6737
NCBI-ProteinID: NP_003132
OMIM: 109092
HGNC: 11312
Ensembl: ENSG00000132109
UniProt: P19474
Structure
LinkDB
Position
11:complement(4384897..4393702)
AA seq 475 aa
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLL
KNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKH
RDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHA
EFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSA
LELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWL
ILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCR
DSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSF
YNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
NT seq 1428 nt   +upstreamnt  +downstreamnt
atggcttcagcagcacgcttgacaatgatgtgggaggaggtcacatgccctatctgcctg
gaccccttcgtggagcctgtgagcatcgagtgtggccacagcttctgccaggaatgcatc
tctcaggttgggaaaggtgggggcagcgtctgtcctgtgtgccggcagcgctttctgctc
aagaatctccggcccaatcgacagctagccaacatggtgaacaaccttaaagaaatcagc
caggaggccagagagggcacacagggggaacggtgtgcagtgcatggagagagacttcac
ctgttctgtgagaaagatgggaaggccctttgctgggtatgtgcccagtctcggaaacac
cgtgaccacgccatggtccctcttgaggaggctgcacaggagtaccaggagaagctccag
gtggcattaggggaactgagaagaaagcaggagttggctgagaagttggaagtggaaatt
gcaataaagagagcagactggaagaaaacagtggaaacacagaaatctaggattcacgca
gagtttgtgcagcaaaaaaacttcctggttgaagaagaacagaggcagctgcaggagctg
gagaaggatgagagggagcagctgagaatcctgggggagaaagaggccaagctggcccag
cagagccaggccctacaggagctcatctcagagctagatcgaaggtgccacagctcagca
ctggaactgctgcaggaggtgataattgtcctggaaaggagtgagtcctggaacctgaag
gacctggatattacctctccagaactcaggagtgtgtgccatgtgccagggctgaagaag
atgctgaggacatgtgcagtccacatcactctggatccagacacagccaatccgtggctg
atactttcagaagatcggagacaagtgaggcttggagacacccagcagagcatacctgga
aatgaagagagatttgatagttatcctatggtcctgggtgcccagcactttcactctgga
aaacattactgggaggtagatgtgacaggaaaggaggcctgggacctgggtgtctgcaga
gactctgtgcgcaggaaggggcactttttgcttagttccaagagtggcttctggacaatt
tggttgtggaacaaacaaaaatatgaggctggcacctacccccagactcccctccacctt
caggtgcctccatgccaagttgggattttcctggactatgaggctggcatggtctccttc
tacaacatcactgaccatggctccctcatctactccttctctgaatgtgcctttacagga
cctctgcggcccttcttcagtcctggtttcaatgatggaggaaaaaacacagcccctcta
accctctgtccactgaatattggatcacaaggatccactgactattga

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