Homo sapiens (human): 6795
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Entry
6795 CDS
T01001
Symbol
AURKC, AIE2, AIK3, ARK3, AurC, HEL-S-90, SPGF5, STK13, aurora-C
Name
(RefSeq) aurora kinase C
KO
K11480
aurora kinase C [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Disease
H01282
Spermatogenic failure
Drug target
Ilorasertib:
D10423
Tozasertib (
DG01365
):
D08279
D08344
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
6795 (AURKC)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
6795 (AURKC)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
6795 (AURKC)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: AGC group
AUR family [OT]
6795 (AURKC)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
6795 (AURKC)
Sister chromatid separation proteins
Aurora kinases
6795 (AURKC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Kinase-like
APH
Kdo
ZMYM4
YrbL-PhoP_reg
Motif
Other DBs
NCBI-GeneID:
6795
NCBI-ProteinID:
NP_001015878
OMIM:
603495
HGNC:
11391
Ensembl:
ENSG00000105146
UniProt:
Q9UQB9
Structure
PDB
PDBj
LinkDB
All DBs
Position
19:57231023..57235548
Genome browser
AA seq
309 aa
AA seq
DB search
MSSPRAVVQLGKAQPAGEELATANQTAQQPSSPAMRRLTVDDFEIGRPLGKGKFGNVYLA
RLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLIL
EYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEV
KIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFE
SASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKHPWVQAHSRRV
LPPCAQMAS
NT seq
930 nt
NT seq
+upstream
nt +downstream
nt
atgagctcccccagagctgtggtgcagctgggcaaagctcaacctgcaggcgaagagttg
gctacagcaaaccaaacagcccagcagcccagcagcccagccatgcggcgcctcacagtc
gatgactttgaaatcgggcgtcccctgggcaaggggaaatttgggaatgtgtacctggct
cggctcaaggaaagccatttcattgtggccctgaaggttctcttcaagtcgcagatagag
aaggaaggactggagcaccagctgcgccgggaaattgagatccaggctcatctacaacac
cccaatatcctgcgcctgtataactatttccatgatgcacgccgggtgtacctgattctg
gaatatgctccaaggggtgagctctacaaggagctgcagaaaagcgagaaattagatgaa
cagcgcacagccacgataatagaggagttggcagatgccctgacctactgccatgacaag
aaagtgattcacagagatattaagccagagaacctgctgctggggttcaggggtgaggtg
aagattgcagattttggctggtctgtgcacaccccctccctgaggaggaagacaatgtgt
gggacactggactacttgccgccagaaatgattgaggggagaacatatgatgaaaaggtg
gatttgtggtgcattggagtgctctgctatgagctgctggtgggatatccaccctttgag
agcgcctcccacagtgagacttacagacgcatcctcaaggtagatgtgaggtttccacta
tcaatgcctctgggggcccgggacttgatttccaggcttctcagataccagcccttggag
agactgcccctggcccagatcctgaagcacccctgggttcaggcccactcccgaagggtg
ctgcctccctgtgctcagatggcttcctga
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