Homo sapiens (human): 6916
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Entry
6916 CDS
T01001
Symbol
TBXAS1, BDPLT14, CYP5, CYP5A1, GHOSAL, THAS, TS, TXAS, TXS
Name
(RefSeq) thromboxane A synthase 1
KO
K01832
thromboxane-A synthase [EC:
5.3.99.5
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00590
Arachidonic acid metabolism
hsa01100
Metabolic pathways
hsa04611
Platelet activation
Disease
H00490
Diaphyseal dysplasia with anemia
Drug target
Dazmegrel:
D03661
Dazoxiben hydrochloride:
D03663
Furegrelate sodium:
D04276
Ozagrel (
DG01256
):
D01683
<JP>
D01684
<JP>
D08327
Picotamide:
D07140
Pirmagrel:
D05502
Ridogrel:
D05727
Terbogrel:
D06077
Trapidil:
D01220
<JP>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
6916 (TBXAS1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
6916 (TBXAS1)
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450 [BR:
hsa00199
]
6916 (TBXAS1)
Enzymes [BR:
hsa01000
]
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.99 Other intramolecular oxidoreductases
5.3.99.5 thromboxane-A synthase
6916 (TBXAS1)
Cytochrome P450 [BR:
hsa00199
]
Cytochrome P450, animal type
CYP5 family
6916 (TBXAS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
p450
Motif
Other DBs
NCBI-GeneID:
6916
NCBI-ProteinID:
NP_001052
OMIM:
274180
HGNC:
11609
Ensembl:
ENSG00000059377
Pharos:
P24557
(Tchem)
UniProt:
P24557
Q53F23
LinkDB
All DBs
Position
7:139778242..140020293
Genome browser
AA seq
533 aa
AA seq
DB search
MEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFFR
QGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV
ADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQR
CYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLA
RILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIV
RDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATN
PDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEV
LGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCL
GVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR
NT seq
1602 nt
NT seq
+upstream
nt +downstream
nt
atggaagccttggggtttctaaaattggaagtgaatggccccatggtgacggtggccctg
tcagtggctctcttggccctcctgaaatggtactccacatcagcattctcaagactggag
aagttaggcctcagacatcccaagccttctcctttcattggaaacttgacatttttccgc
cagggtttttgggaaagccaaatggagctcagaaagctgtatggacctctgtgtgggtac
tatcttggtcgtcggatgtttattgttatttctgagccagacatgatcaagcaggtgttg
gttgagaacttcagtaactttaccaacagaatggcgtcgggtttggagttcaagtcggta
gccgacagcgttctgtttttacgtgacaaaagatgggaagaggtcagaggtgccctgatg
tctgctttcagtcctgaaaagctgaacgagatggttcccctcatcagccaagcctgcgac
cttctcctggctcatttaaaacgctatgcggaatctggggacgcatttgacatccagagg
tgctactgcaattacaccacagatgtggttgccagcgtcgcctttggcaccccggtggac
tcctggcaggcccctgaggatccctttgtgaaacactgcaagcgtttcttcgaattctgc
atccccagacctatcctggttttactcttatcatttccatccataatggtcccactggcc
cggattttgcccaataagaaccgagacgaactgaatggcttttttaacaaactcattagg
aatgtgattgccttgcgggaccagcaagctgccgaagagaggcggagagacttcctccaa
atggtcctggatgcccgacattctgcaagtcccatgggcgtgcaagactttgacatcgtc
agagacgttttctcctctactgggtgcaagccgaacccttcccggcaacaccagcccagc
cctatggccaggcctttgactgtggatgagattgtgggccaggccttcatcttcctcatc
gctggctatgaaatcatcaccaacacactttcttttgccacctacctactggccaccaac
cctgactgccaagagaagcttctgagagaggtagacgtttttaaggagaaacacatggcc
cctgagttctgcagcctcgaggaaggcctgccctatctggacatggtgattgcagagacg
ctgaggatgtacccgccagctttcagattcacacgggaggcagctcaggactgcgaggtg
ctggggcagcgcatccccgcaggcgctgtgctagagatggccgtgggtgccctgcaccat
gaccctgagcactggccaagcccggagaccttcaaccctgaaaggttcacggctgaggcc
cggcagcagcaccggcccttcacgtacctgcccttcggggccggcccacggagctgcctc
ggggtgcgtctagggctgcttgaggtcaagttgacactgctccacgtgctgcacaagttc
cggttccaagcctgccctgagacccaggtaccgctgcagctagaatccaaatctgcccta
ggtccaaaaaatggtgtctatatcaagatcgtatcccgctga
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