Homo sapiens (human): 7064
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Entry
7064 CDS
T01001
Symbol
THOP1, EP24.15, MEPD_HUMAN, MP78, TOP
Name
(RefSeq) thimet oligopeptidase 1
KO
K01392
thimet oligopeptidase [EC:
3.4.24.15
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04614
Renin-angiotensin system
hsa05143
African trypanosomiasis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09152 Endocrine system
04614 Renin-angiotensin system
7064 (THOP1)
09160 Human Diseases
09174 Infectious disease: parasitic
05143 African trypanosomiasis
7064 (THOP1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
7064 (THOP1)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.15 thimet oligopeptidase
7064 (THOP1)
Peptidases and inhibitors [BR:
hsa01002
]
Metallo peptidases
Family M3
7064 (THOP1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_M3
ABCA12_C
TOP_N
Motif
Other DBs
NCBI-GeneID:
7064
NCBI-ProteinID:
NP_003240
OMIM:
601117
HGNC:
11793
Ensembl:
ENSG00000172009
UniProt:
P52888
Structure
PDB
PDBj
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All DBs
Position
19:2785503..2815807
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AA seq
689 aa
AA seq
DB search
MKPPAACAGDMADAASPCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVS
YESTLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQ
RIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNK
NLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKV
EEAFNCRCKEENCAILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQ
KLKPLGEQERAVILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYF
PVQVVTHGLLGIYQELLGLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREG
KYGHAACFGLQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMH
QLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLI
ESRQANTGLFNLRQIVLAKVDQALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGH
LAGGYDAQYYGYLWSEVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRR
FLGRDPKQDAFLLSKGLQVGGCEPEPQVC
NT seq
2070 nt
NT seq
+upstream
nt +downstream
nt
atgaagccccccgcagcctgtgcaggagacatggcggacgcagcatctccgtgctctgtg
gtaaacgacctgcggtgggacctgagtgcccagcagatagaggagcgcaccagggagctc
atcgagcagaccaagcgcgtgtatgaccaggttggcacccaggagtttgaggacgtgtcc
tacgagagcacgctcaaggcgctggccgatgtggaggtcacctacacagttcagaggaat
atccttgacttcccccagcatgtttccccctccaaggacatccggacagccagcacagag
gccgacaagaagctctctgagttcgacgtggagatgagcatgagggaggacgtgtaccag
aggatcgtgtggctccaggagaaagttcagaaggactcactgaggcccgaggctgcgcgg
tacctggagcggctaatcaagctgggccggagaaatgggcttcacctccccagagagact
caggaaaacatcaaacgcatcaagaagaagctgagccttctgtgcatcgacttcaacaag
aacctgaacgaggacacgaccttcctgcccttcacgctccaggagctaggagggctcccc
gaggactttctgaactccctggagaagatggaggacggcaagttgaaggtcaccctcaag
tacccccattacttccccctcctgaagaaatgccacgtgcctgagaccaggaggaaagtg
gaggaggccttcaactgccggtgcaaggaggagaactgcgctatcctcaaggagctggtg
acgctgcgggcccagaagtcccgcctgctggggttccacacgcacgccgactatgtcctg
gagatgaacatggccaagaccagccagaccgtggccaccttcctagatgagctggcgcag
aagctgaagcccctgggggagcaggagcgtgcggtgattctggagctgaagcgtgcggag
tgcgagcgccggggcctgcccttcgacggccgcatccgtgcctgggacatgcgctactac
atgaaccaggtggaggagacgcgctactgcgtggaccagaacctgctcaaggagtacttc
cccgtgcaggtggtcacgcacgggctgctgggcatctaccaggagctcctggggctggcc
ttccaccacgaggagggcgccagtgcctggcatgaggacgtgcggctctacaccgcgagg
gacgcggcctcgggggaggtggtcggcaagttctacctggacctgtacccgcgggaagga
aagtacgggcacgcggcctgctttggcctgcagcccggctgcctgcggcaggatgggagc
cgccagatcgccatcgcggccatggtggccaacttcaccaagcccacagccgacgcgccc
tcgctgctgcagcatgacgaggtggagacctacttccatgagtttggccacgtgatgcac
cagctctgctcccaggcggagttcgccatgttcagcgggacccacgtggagcgggacttt
gtggaggcgccgtcgcagatgctggagaactgggtgtgggagcaggagccgctgctgcgg
atgtcgcggcactaccgcacaggcagcgccgtgccccgggagctcctggagaagctcatt
gagtcccggcaggccaacacaggcctcttcaacctgcgccagatcgtcctcgccaaggtg
gaccaggccctgcacacgcagacggacgcagaccccgccgaggagtatgcgcggctctgc
caggagatcctcggggtcccggccacgccaggaaccaacatgcctgcaaccttcggccat
ctggcaggtggctacgacgcccagtactacgggtacctgtggagcgaggtgtattccatg
gacatgttccacacgcgcttcaagcaggagggtgtcctgaacagcaaggttggcatggat
tacagaagctgcatcctgagacccggcggttccgaggatgccagcgccatgctgaggcgc
ttcctgggccgtgaccccaagcaggacgccttcctcctgagcaaggggctgcaggtcggg
ggctgcgagcccgagccgcaggtctgctga
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