Homo sapiens (human): 7100 Help Entry 7100              CDS       T01001                                  Symbol TLR5, MELIOS, SLE1, SLEB1, TIL3 Name (RefSeq) toll like receptor 5   KO K10168   toll-like receptor 5 Organism hsa  Homo sapiens (human) Pathway hsa04620   Toll-like receptor signaling pathway hsa05130   Pathogenic Escherichia coli infection hsa05131   Shigellosis hsa05132   Salmonella infection hsa05134   Legionellosis hsa05321   Inflammatory bowel disease Network nt06517  TLR signaling   Element N01566   TLR5-NFKB signaling pathway Disease H00080   Systemic lupus erythematosus H00311   Legionellosis H00317   Melioidosis Drug target Entolimod:  D10368 Brite KEGG Orthology (KO) [BR:hsa00001]  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     7100 (TLR5)  09160 Human Diseases   09171 Infectious disease: bacterial    05130 Pathogenic Escherichia coli infection     7100 (TLR5)    05132 Salmonella infection     7100 (TLR5)    05131 Shigellosis     7100 (TLR5)    05134 Legionellosis     7100 (TLR5)   09163 Immune disease    05321 Inflammatory bowel disease     7100 (TLR5)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:hsa04054]     7100 (TLR5) Pattern recognition receptors [BR:hsa04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    7100 (TLR5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 TIR LRR_4 LRR_1 LRR_5 TIR_2 LRR_9 LRRCT CoV_E Motif Other DBs NCBI-GeneID:  7100 NCBI-ProteinID:  NP_003259 OMIM:  603031 HGNC:  11851 Ensembl:  ENSG00000187554 UniProt:  O60602 A0A2R8Y7Z4 Structure PDB LinkDB All DBs Position 1:complement(223109404..223143248) Genome browser AA seq 858 aa AA seqDB search MGDHLDLLLGVVLMAGPVFGIPSCSFDGRIAFYRFCNLTQVPQVLNTTERLLLSFNYIRT VTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPDAFQGLFH LFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLKSIDFSSN QIFLVCEHELEPLQGKTLSFFSLAANSLYSRVSVDWGKCMNPFRNMVLEILDVSGNGWTV DITGNFSNAISKSQAFSLILAHHIMGAGFGFHNIKDPDQNTFAGLARSSVRHLDLSHGFV FSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLLGELYSSNFYGLP KVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIHFIPSIPDIFLSGNKLVTLPK INLTANLIHLSENRLENLDILYFLLRVPHLQILILNQNRFSSCSGDQTPSENPSLEQLFL GENMLQLAWETELCWDVFEGLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTV LSHNDLPANLEILDISRNQLLAPNPDVFVSLSVLDITHNKFICECELSTFINWLNHTNVT IAGPPADIYCVYPDSFSGVSLFSLSTEGCDEEEVLKSLKFSLFIVCTVTLTLFLMTILTV TKFRGFCFICYKTAQRLVFKDHPQGTEPDMYKYDAYLCFSSKDFTWVQNALLKHLDTQYS DQNRFNLCFEERDFVPGENRIANIQDAIWNSRKIVCLVSRHFLRDGWCLEAFSYAQGRCL SDLNSALIMVVVGSLSQYQLMKHQSIRGFVQKQQYLRWPEDLQDVGWFLHKLSQQILKKE KEKKKDNNIPLQTVATIS NT seq 2577 nt NT seq  +upstreamnt  +downstreamnt atgggagaccacctggaccttctcctaggagtggtgctcatggccggtcctgtgtttgga attccttcctgctcctttgatggccgaatagccttttatcgtttctgcaacctcacccag gtcccccaggtcctcaacaccactgagaggctcctgctgagcttcaactatatcaggaca gtcactgcttcatccttcccctttctggaacagctgcagctgctggagctcgggagccag tatacccccttgactattgacaaggaggccttcagaaacctgcccaaccttagaatcttg gacctgggaagtagtaagatatacttcttgcatccagatgcttttcagggactgttccat ctgtttgaacttagactgtatttctgtggtctctctgatgctgtattgaaagatggttat ttcagaaatttaaaggctttaactcgcttggatctatccaaaaatcagattcgtagcctt taccttcatccttcatttgggaagttgaattccttaaagtccatagatttttcctccaac caaatattccttgtatgtgaacatgagctcgagcccctacaagggaaaacgctctccttt tttagcctcgcagctaatagcttgtatagcagagtctcagtggactggggaaaatgtatg aacccattcagaaacatggtgctggagatactagatgtttctggaaatggctggacagtg gacatcacaggaaactttagcaatgccatcagcaaaagccaggccttctctttgattctt gcccaccacatcatgggtgccgggtttggcttccataacatcaaagatcctgaccagaac acatttgctggcctggccagaagttcagtgagacacctggatctttcacatgggtttgtc ttctccctgaactcacgagtctttgagacactcaaggatttgaaggttctgaaccttgcc tacaacaagataaataagattgcagatgaagcattttacggacttgacaacctccaagtt ctcaatttgtcatataaccttctgggggaactttacagttcgaatttctatggactacct aaggtagcctacattgatttgcaaaagaatcacattgcaataattcaagaccaaacattc aaattcctggaaaaattacagaccttggatctccgagacaatgctcttacaaccattcat tttattccaagcatacccgatatcttcttgagtggcaataaactagtgactttgccaaag atcaaccttacagcgaacctcatccacttatcagaaaacaggctagaaaatctagatatt ctctactttctcctacgggtacctcatctccagattctcattttaaatcaaaatcgcttc tcctcctgtagtggagatcaaaccccttcagagaatcccagcttagaacagcttttcctt ggagaaaatatgttgcaacttgcctgggaaactgagctctgttgggatgtttttgaggga ctttctcatcttcaagttctgtatttgaatcataactatcttaattcccttccaccagga gtatttagccatctgactgcattaaggggactaagcctcaactccaacaggctgacagtt ctttctcacaatgatttacctgctaatttagagatcctggacatatccaggaaccagctc ctagctcctaatcctgatgtatttgtatcacttagtgtcttggatataactcataacaag ttcatttgtgaatgtgaacttagcacttttatcaattggcttaatcacaccaatgtcact atagctgggcctcctgcagacatatattgtgtgtaccctgactcgttctctggggtttcc ctcttctctctttccacggaaggttgtgatgaagaggaagtcttaaagtccctaaagttc tcccttttcattgtatgcactgtcactctgactctgttcctcatgaccatcctcacagtc acaaagttccggggcttctgttttatctgttataagacagcccagagactggtgttcaag gaccatccccagggcacagaacctgatatgtacaaatatgatgcctatttgtgcttcagc agcaaagacttcacatgggtgcagaatgctttgctcaaacacctggacactcaatacagt gaccaaaacagattcaacctgtgctttgaagaaagagactttgtcccaggagaaaaccgc attgccaatatccaggatgccatctggaacagtagaaagatcgtttgtcttgtgagcaga cacttccttagagatggctggtgccttgaagccttcagttatgcccagggcaggtgctta tctgaccttaacagtgctctcatcatggtggtggttgggtccttgtcccagtaccagttg atgaaacatcaatccatcagaggctttgtacagaaacagcagtatttgaggtggcctgag gatctccaggatgttggctggtttcttcataaactctctcaacagatactaaagaaagaa aaagaaaagaagaaagacaataacattccgttgcaaactgtagcaaccatctcctaa

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