KEGG   Homo sapiens (human): 7290
Entry
7290              CDS       T01001                                 
Symbol
HIRA, DGCR1, TUP1, TUPLE1
Name
(RefSeq) histone cell cycle regulator
  KO
K11293  protein HIRA/HIR1
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    7290 (HIRA)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Nucleosome assembly factors
   Histone chaperones
    Other Histone chaperones and regulators
     7290 (HIRA)
SSDB
Motif
Pfam: Hira Beta-prop_CAF1B_HIR1 WD40 WD40_Prp19 WD40_CDC20-Fz WD40_WDHD1_1st Beta-prop_EML_2 Beta-prop_TEP1_2nd WDR55 ANAPC4_WD40 EIF3I WD40_MABP1-WDR62_2nd Beta-prop_WDR35_TULP_N Beta-prop_IFT140_1st Beta-prop_IFT122_1st Beta-prop_RIG_2nd Beta-prop_WDR75_1st Beta-prop_WDR90_POC16_2nd Beta-prop_HPS5 Beta-prop_WDR19_1st NBCH_WD40 HIRA_B Mcl1_mid WDR90_beta-prop_4th WD40_like
Other DBs
NCBI-GeneID: 7290
NCBI-ProteinID: NP_003316
OMIM: 600237
HGNC: 4916
Ensembl: ENSG00000100084
UniProt: P54198
Structure
LinkDB
Position
22:complement(19330698..19431733)
AA seq 1017 aa
MKLLKPTWVNHNGKPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIP
KMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQ
WRCVSILRNHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGL
TWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSA
HAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSAKPSCPYCCC
AVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQD
ELGDPLSEEEKSRIHQSTYGKSLAIMTEAQLSTAVIENPEMLKYQRRQQQQQLDQKSAAT
REMGSATSVAGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSTAFFN
SIPLSGSLAGTMLSSHSSPQLLPLDSSTPNSFGASKPCTEPVVAASARPAGDSVNKDSMN
ATSTPAALSPSVLTTPSKIEPMKAFDSRFTERSKATPGAPALTSMTPTAVERLKEQNLVK
ELRPRDLLESSSDSDEKVPLAKASSLSKRKLELEVETVEKKKKGRPRKDSRLMPVSLSVQ
SPAALTAEKEAMCLSAPALALKLPIPSPQRAFTLQVSSDPSMYIEVENEVTVVGGVKLSR
LKCNREGKEWETVLTSRILTAAGSCDVVCVACEKRMLSVFSTCGRRLLSPILLPSPISTL
HCTGSYVMALTAAATLSVWDVHRQVVVVKEESLHSILAGSDMTVSQILLTQHGIPVMNLS
DGKAYCFNPSLSTWNLVSDKQDSLAQCADFRSSLPSQDAMLCSGPLAIIQGRTSNSGRQA
ARLFSVPHVVQQETTLAYLENQVAAALTLQSSHEYRHWLLVYARYLVNEGFEYRLREICK
DLLGPVHYSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFTECQEQLDILRDK
NT seq 3054 nt   +upstreamnt  +downstreamnt
atgaagctcctgaagccgacctgggtcaaccacaatggcaagccgattttttcagttgat
attcaccctgacgggaccaagttcgcaactggaggacaagggcaggattctgggaaggtt
gtgatctggaatatgtctccagtcctccaggaggatgacgagaaggatgaaaatattccc
aagatgctttgccagatggacaatcacttagcatgtgtgaactgtgtgcggtggtcaaac
agtgggatgtatttagcttctgggggagatgacaaactgattatggtgtggaagcgggct
acgtacatcggccccagcaccgtgttcggctccagtggtaagcttgccaatgtggagcag
tggcggtgtgtctctatcctccggaatcattcaggcgatgtgatggatgtagcatggtct
ccccacgatgcctggctagcctcatgcagcgtggataacactgtcgtcatctggaatgct
gtaaagttcccagaaattctagctactctgagaggtcattctggcttggtcaaagggttg
acatgggaccctgttggtaaatacatagcttctcaagctgatgaccgcagcctaaaggtg
tggaggacgctggactggcagttggagaccagcatcaccaagccttttgatgagtgtgga
ggaacgacccatgtgttgcggctcagctggtcacctgatgggcattacctggtgtctgcc
catgccatgaacaactcaggccccactgcccagatcatcgaacgggagggatggaagacc
aacatggactttgttgggcaccggaaagctgtgactgtcgtgaaattcaacccaaaaatc
ttcaaaaagaagcagaagaatgggagttctgcgaagcctagctgcccgtactgctgctgt
gctgttggcagcaaggaccgctcgctttctgtctggctcacatgtctgaaacggccgctg
gtggtcatccatgaactgtttgacaaatccatcatggatatttcctggactctgaatggg
ctgggcatcttggtatgctctatggacggctctgtggcattcctcgacttctcccaggat
gagcttggcgatcccctgagcgaggaggagaagagccgcattcaccagtccacctatggc
aagagcctagccatcatgaccgaggcccagctctccacagccgtcattgagaaccctgag
atgctcaagtaccagcgaaggcagcagcagcagcagctggaccagaagagtgctgcgacc
agggagatgggctcagccacctcagtcgcaggcgttgtcaacggggagagtcttgaagat
atcaggaagaatcttttgaagaaacaagttgagactcggacagcagatggccggagaaga
atcacgcctctctgcatagcacagctggacactggggacttctccacggcattctttaac
agcatccccctctcgggctccctggcgggcaccatgctctcttctcatagcagtccacag
ctactgccactggactccagtacccctaactccttcggcgcctcgaagccttgcacagag
cctgtggtggctgccagtgccagacctgcaggcgattctgtcaataaagacagtatgaat
gctacctctactcctgctgcattgtcaccttctgtgttaacgaccccgtccaagatcgaa
cccatgaaagcgtttgactcccggttcacagagcggtccaaagccacaccaggtgctcct
gccctgaccagcatgactccgacagctgtggaaaggttaaaagagcagaaccttgtgaaa
gagctgaggccccgagacctcctggagagcagcagtgacagcgatgagaaagtccctttg
gctaaggcttcctcactgtccaagcgaaaacttgagcttgaggtagagacagtagagaag
aagaagaaagggcggcctcggaaggactctcgtctcatgcctgtgtctctgtctgtccag
tctccagctgccctaaccgcagagaaggaggccatgtgtctgtctgcaccagcacttgca
ctgaagctgccaattccaagcccccagagagcattcaccctccaggtcagctccgatcct
tccatgtacattgaggtggagaatgaagtgacagtggtggggggcgtgaagctgagccgc
ctgaagtgcaaccgggaagggaaggagtgggagacggtactcaccagccggatcctcact
gctgcgggcagctgtgacgtggtgtgtgtcgcctgtgaaaaaaggatgctgtcagtgttc
tccacctgtggtcgccgtctcctctctcccatcctcctgccatccccgatctctactttg
cattgcacaggctcctacgtcatggcgctcaccgctgcagccacactctctgtctgggat
gttcacagacaggtggttgtggtgaaagaagagtctctacactccatcctggcaggaagt
gatatgacggtatcacagatcttgctgacgcagcatggaatcccagtaatgaacctgtcc
gatgggaaggcgtactgctttaatccgtcactttccacatggaacctggtttctgacaag
caggactcactggctcagtgtgcagactttaggagcagcctgccatcccaggacgccatg
ctgtgctcaggaccgttagccataatccagggccgcacctccaactcgggaaggcaggct
gcccggctcttctccgtgcctcatgtggtgcagcaagagaccaccctggcctacctagag
aaccaggtggcagcagcactcaccctgcagtccagccacgagtaccgccattggctcctc
gtctacgcacggtacctcgtaaacgaagggtttgaataccgacttcgagaaatatgcaag
gacttactgggtccggttcactactccactggaagccagtgggagtcaacagtagtgggt
ctgcggaagagggagctgctgaaggagctgctaccagtcatcgggcagaacctccgattc
cagcgcctcttcaccgagtgtcaggaacagctcgacatcctgagggacaagtag

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