Homo sapiens (human): 729438
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Entry
729438 CDS
T01001
Symbol
CASTOR2, GATSL1, GATSL2
Name
(RefSeq) cytosolic arginine sensor for mTORC1 subunit 2
KO
K23081
cytosolic arginine sensor for mTORC1 subunit 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04150
mTOR signaling pathway
Drug target
Sapanisertib:
D11183
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04150 mTOR signaling pathway
729438 (CASTOR2)
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Gene cluster
GFIT
Motif
Pfam:
CASTOR1_ACT-like
ACT_7
Castor1_N
Motif
Other DBs
NCBI-GeneID:
729438
NCBI-ProteinID:
NP_001138536
OMIM:
617033
HGNC:
37073
Ensembl:
ENSG00000274070
UniProt:
A6NHX0
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Position
7:74964705..75031528
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AA seq
329 aa
AA seq
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MELHILEHRLQVASVAKESIPLFTYGLIKLAFLSSKTRCKFFSLTETPEDYTIIVDEEGF
LELPSSEHLSVADATWLALNVVSGGGSFSSSQPIGVTKIAKSVIAPLADQNISVFMLSTY
QTDFILVRERDLPFVTHTLSSEFTILRVVNGETVAAENLGITNGFVKPKLVQRPVIHPLS
SPSNRFCVTSLDPDTLPAVATLLMDVMFYSNGVKDPMATGDDCGHIRFFSFSLIEGYISL
VMDVQTQQRFPSNLLFTSASGELWKMVRIGGQPLGFDECGIVAQISEPLAAADIPAYYIS
TFKFDHALVPEENINGVISALKVSQAEKH
NT seq
990 nt
NT seq
+upstream
nt +downstream
nt
atggaactccacatcctggagcaccggctgcaagttgccagcgtcgccaaggagagtatc
ccgctgttcacctacggcctgatcaaacttgccttcctgtcctccaagaccaggtgcaag
ttcttcagtctgactgagacgccagaggattacactatcattgtcgatgaggaaggattc
ctagagctgccctcctcggagcacctgagtgtggcagatgccacctggctggccctgaac
gtggtgtccggcggtggcagcttctccagctcccagcccatcggcgtgaccaagatcgcc
aagtcagtcatcgccccactggctgaccagaacatatccgtgttcatgctgtccacgtat
cagacagacttcatcctggtgcgcgagcgggacctgccctttgtcacccacacattgtca
tcagagttcaccatcctgcgggtcgtcaatggcgagaccgtggcagccgagaacctcggc
atcaccaatggcttcgtgaagcccaagctggtccagaggccagtcatccacccactgtcc
agcccgagcaacaggttctgtgtcaccagcctggaccctgacacgctgcctgctgttgcc
acactcctcatggatgtcatgttctactccaatggagtgaaggaccccatggccactggg
gatgactgcggccacatccgcttcttctccttctccctcatcgagggctacatctccctg
gtgatggacgtgcagacgcagcagaggtttcctagtaacttgctgttcacaagcgcatcc
ggagagctctggaagatggtccggattggaggacagcccctggggtttgatgagtgtggc
atcgtggcccagatctcagagcccttggctgctgcagacatcccagcctactacatcagt
actttcaagtttgatcatgcacttgtccccgaagagaacatcaatggtgtcatcagtgcc
ctgaaggtcagccaagcagagaagcactag
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integrated database retrieval system
