Homo sapiens (human): 7318
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Entry
7318 CDS
T01001
Symbol
UBA7, D8, UBA1B, UBE1L, UBE2, UBE7
Name
(RefSeq) ubiquitin like modifier activating enzyme 7
KO
K10698
ubiquitin-activating enzyme E1-like [EC:
6.2.1.45
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04120
Ubiquitin mediated proteolysis
hsa05012
Parkinson disease
hsa05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
7318 (UBA7)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
7318 (UBA7)
05022 Pathways of neurodegeneration - multiple diseases
7318 (UBA7)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
7318 (UBA7)
Enzymes [BR:
hsa01000
]
6. Ligases
6.2 Forming carbon-sulfur bonds
6.2.1 Acid-thiol ligases
6.2.1.45 E1 ubiquitin-activating enzyme
7318 (UBA7)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin-activating enzymes (E1)
UBL-activating enzymes
7318 (UBA7)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ThiF
UBA_E1_SCCH
E1_FCCH
E1_UFD
E1_4HB
Motif
Other DBs
NCBI-GeneID:
7318
NCBI-ProteinID:
NP_003326
OMIM:
191325
HGNC:
12471
Ensembl:
ENSG00000182179
UniProt:
P41226
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:complement(49805209..49813953)
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AA seq
1012 aa
AA seq
DB search
MDALDASKLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLT
LHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQ
VVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAA
IQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGD
TTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKF
QHLHGRPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPM
VAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIA
VFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQ
FLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALD
SFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCT
VRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLR
VRPQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTN
QDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLELASASA
EFGPEQQKELNKALEVWSVGPPLKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRA
QSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFA
PAIQTFHHLKWTSWDRLKVPAGQPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSP
EKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDDEDTAFPPLHYEL
NT seq
3039 nt
NT seq
+upstream
nt +downstream
nt
atggatgccctggacgcttcgaagctactggatgaggagctgtattcaagacagctgtat
gtgctgggctcacctgccatgcagaggattcagggagccagggtcctggtgtcaggcctg
cagggcctgggggccgaggtggccaagaacttggttctgatgggtgtgggcagcctcact
ctgcatgatccccaccccacctgctggtccgacctggctgcccagtttctcctctcagag
caggacttggaaaggagcagagccgaggcctctcaagagctcttggctcagctcaacaga
gctgtccaggtcgtcgtgcacacgggtgacatcactgaggacctgctgttggacttccag
gtggtggtgctgactgctgcaaagctggaggagcagctgaaggtgggcaccttgtgtcat
aagcatggagtttgctttctggcggctgacacccggggcctcgtggggcagttgttctgt
gactttggtgaggacttcactgtgcaggaccccacagaggcagaacccctgacagctgcc
atccagcacatctcccagggctcccctggcattctcactctgaggaaaggggccaatacc
cactacttccgtgatggagacttggtgactttctcgggaattgagggaatggttgagctc
aacgactgtgatccccggtctatccacgtgcgggaggatgggtccctggagattggagac
acaacaactttctctcggtacttgcgtggtggggctatcactgaagtcaagagacccaag
actgtgagacataagtccctggacacagccctgctccagccccatgtggtggcccagagc
tcccaggaagttcaccatgcccactgcctgcatcaggccttctgtgcactgcacaagttc
cagcacctccatggccggccaccccagccctgggatcctgttgatgcagagactgtggtg
ggcctggcccgggacctggaaccactgaagcggacagaggaagagccactggaagagcca
ctggatgaggccctagtgcggacagtcgccctaagcagtgcaggtgtcttgagccctatg
gtggccatgctgggtgcagtagctgcccaggaagtgctgaaggcaatctccaggaagttc
atgcctctggaccagtggctttactttgatgccctcgattgtcttccggaagatggggag
ctccttcccagtcctgaggactgtgccctgagaggcagccgctatgatgggcaaattgca
gtgtttggggctggttttcaggagaaactgagacgccagcactacctcctggtgggcgct
ggtgccattggttgtgagctgctcaaagtctttgccctagtgggactgggggccgggaac
agcgggggcttgactgttgttgacatggaccacatagagcgctccaatctcagccgtcag
ttcctcttcaggtcccaggacgttggtagacccaaggcagaggtggctgcagcagctgcc
cggggcctgaacccagacttacaggtgatcccgctcacctacccactggatcccaccaca
gagcacatctatggggataactttttctcccgtgtggatggtgtggctgctgccctggac
agtttccaggcccggcgctatgtggctgctcgttgcacccactatctgaagccactgctg
gaggcaggcacatcgggcacctggggcagtgctacagtattcatgccacatgtgactgag
gcctacagagcccctgcctcagctgcagcttctgaggatgccccctaccctgtctgtacc
gtgcggtacttccctagcacagccgagcacaccctgcagtgggcccggcatgagtttgaa
gaactcttccgactgtctgcagagaccatcaaccaccaccaacaggcacacacttccctg
gcagacatggatgagccacagacactcaccttactgaagccagtgcttggggtcctgaga
gtgcgtccacagaactggcaagactgtgtggcgtgggctcttggccactggaaactctgc
tttcattatggcatcaaacagctgctgaggcacttcccacctaataaagtgcttgaggat
ggaactcccttctggtcaggtcccaaacagtgtccccagcccttggagtttgacaccaac
caagacacacacctcctctacgtactggcagctgccaacctgtatgcccagatgcatggg
ctgcctggctcacaggactggactgcactcagggagctgctgaagctgctgccacagcct
gacccccaacagatggcccccatctttgctagtaatctagagctggcttcggcttctgct
gagtttggccctgagcagcagaaggaactgaacaaagccctggaagtctggagtgtgggc
cctcccctgaagcctctgatgtttgagaaggatgatgacagcaacttccatgtggacttt
gtggtagcggcagctagcctgagatgtcagaactacgggattccaccggtcaaccgtgcc
cagagcaagcgaattgtgggccagattatcccagccattgccaccactacagcagctgtg
gcaggcctgttgggcctggagctgtataaggtggtgagtgggccacggcctcgtagtgcc
tttcgccacagctacctacatctggctgaaaactacctcatccgctatatgccttttgcc
ccagccatccagacgttccatcacctgaagtggacctcttgggaccgtctgaaggtacca
gctgggcagcctgagaggaccctggagtcgctgctggctcatcttcaggagcagcacggg
ttgagggtgaggatcctgctgcacggctcagccctgctctatgcggccggatggtcacct
gaaaagcaggcccagcacctgcccctcagggtgacagaactggttcagcagctgacaggc
caggcacctgctcctgggcagcgggtgttggtgctagagctgagctgtgagggtgacgac
gaggacactgccttcccacctctgcactatgagctgtga
DBGET
integrated database retrieval system
