Homo sapiens (human): 7372 Help Entry 7372              CDS       T01001                                  Symbol UMPS, OPRT Name (RefSeq) uridine monophosphate synthetase   KO K13421   uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23] Organism hsa  Homo sapiens (human) Pathway hsa00240   Pyrimidine metabolism hsa00983   Drug metabolism - other enzymes hsa01100   Metabolic pathways hsa01240   Biosynthesis of cofactors Module hsa_M00051   De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP Disease H00198   Orotic aciduria Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09104 Nucleotide metabolism    00240 Pyrimidine metabolism     7372 (UMPS)   09111 Xenobiotics biodegradation and metabolism    00983 Drug metabolism - other enzymes     7372 (UMPS) Enzymes [BR:hsa01000]  2. Transferases   2.4  Glycosyltransferases    2.4.2  Pentosyltransferases     2.4.2.10  orotate phosphoribosyltransferase      7372 (UMPS)  4. Lyases   4.1  Carbon-carbon lyases    4.1.1  Carboxy-lyases     4.1.1.23  orotidine-5'-phosphate decarboxylase      7372 (UMPS) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  OMPdecase Pribosyltran Motif Other DBs NCBI-GeneID:  7372 NCBI-ProteinID:  NP_000364 OMIM:  613891 HGNC:  12563 Ensembl:  ENSG00000114491 UniProt:  P11172 A8K5J1 Structure PDBPDBj LinkDB All DBs Position 3:124730452..124749273 Genome browser AA seq 480 aa AA seqDB search MAVARAALGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRPRLLSQVADILFQT AQNAGISFDTVCGVPYTALPLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGETCL IIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKML EILEQQKKVDAETVGRVKRFIQENVFVAANHNGSPLSIKEAPKELSFGARAELPRIHPVA SKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELIT LAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLP LHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQ LEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLGV NT seq 1443 nt NT seq  +upstreamnt  +downstreamnt atggcggtcgctcgtgcagctttggggccattggtgacgggtctgtacgacgtgcaggct ttcaagtttggggacttcgtgctgaagagcgggctttcctcccccatctacatcgatctg cggggcatcgtgtctcgaccgcgtcttctgagtcaggttgcagatattttattccaaact gcccaaaatgcaggcatcagttttgacaccgtgtgtggagtgccttatacagctttgcca ttggctacagttatctgttcaaccaatcaaattccaatgcttattagaaggaaagaaaca aaggattatggaactaagcgtcttgtagaaggaactattaatccaggagaaacctgttta atcattgaagatgttgtcaccagtggatctagtgttttggaaactgttgaggttcttcag aaggagggcttgaaggtcactgatgccatagtgctgttggacagagagcagggaggcaag gacaagttgcaggcgcacgggatccgcctccactcagtgtgtacattgtccaaaatgctg gagattctcgagcagcagaaaaaagttgatgctgagacagttgggagagtgaagaggttt attcaggagaatgtctttgtggcagcgaatcataatggttctcccctttctataaaggaa gcacccaaagaactcagcttcggtgcacgtgcagagctgcccaggatccacccagttgca tcgaagcttctcaggcttatgcaaaagaaggagaccaatctgtgtctatctgctgatgtt tcactggccagagagctgttgcagctagcagatgctttaggacctagtatctgcatgctg aagactcatgtagatattttgaatgattttactctggatgtgatgaaggagttgataact ctggcaaaatgccatgagttcttgatatttgaagaccggaagtttgcagatataggaaac acagtgaaaaagcagtatgaaggaggtatctttaaaatagcttcctgggcagatctagta aatgctcacgtggtgccaggctcaggagttgtgaaaggcctgcaagaagtgggcctgcct ttgcatcgggggtgcctccttattgcggaaatgagctccaccggctccctggccactggg gactacactagagcagcggttagaatggctgaggagcactctgaatttgttgttggtttt atttctggctcccgagtaagcatgaaaccagaatttcttcacttgactccaggagttcag ttggaagcaggaggagataatcttggccaacagtacaatagcccacaagaagttattggc aaacgaggttccgatatcatcattgtaggtcgtggcataatctcagcagctgatcgtctg gaagcagcagagatgtacagaaaagctgcttgggaagcgtatttgagtagacttggtgtt tga

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