Homo sapiens (human): 7442
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Entry
7442 CDS
T01001
Symbol
TRPV1, VR1
Name
(RefSeq) transient receptor potential cation channel subfamily V member 1
KO
K05222
transient receptor potential cation channel subfamily V member 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04750
Inflammatory mediator regulation of TRP channels
Drug target
Capsaicin:
D00250
<US>
Mavatrep:
D10370
Motugivatrep:
D12841
Nonivamide:
D08282
Olvanil:
D05249
Zucapsaicin:
D06388
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
7442 (TRPV1)
09150 Organismal Systems
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
7442 (TRPV1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
7442 (TRPV1)
Ion channels [BR:
hsa04040
]
Voltage-gated cation channels
Transient receptor potential channel (TRP)
7442 (TRPV1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ank_2
Ank
Ion_trans
Ank_3
Ank_5
Motif
Other DBs
NCBI-GeneID:
7442
NCBI-ProteinID:
NP_061197
OMIM:
602076
HGNC:
12716
Ensembl:
ENSG00000196689
UniProt:
Q8NER1
Structure
PDB
PDBj
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All DBs
Position
17:complement(3565446..3609411)
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AA seq
839 aa
AA seq
DB search
MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP
VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE
AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI
ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT
KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA
DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE
PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN
RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL
SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS
MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE
DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF
IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA
FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS
SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK
NT seq
2520 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaatggagcagcacagacttgggggcagctgcggacccactccaaaaggacacc
tgcccagaccccctggatggagaccctaactccaggccacctccagccaagccccagctc
tccacggccaagagccgcacccggctctttgggaagggtgactcggaggaggctttcccg
gtggattgccctcacgaggaaggtgagctggactcctgcccgaccatcacagtcagccct
gttatcaccatccagaggccaggagacggccccaccggtgccaggctgctgtcccaggac
tctgtcgccgccagcaccgagaagaccctcaggctctatgatcgcaggagtatctttgaa
gccgttgctcagaataactgccaggatctggagagcctgctgctcttcctgcagaagagc
aagaagcacctcacagacaacgagttcaaagaccctgagacagggaagacctgtctgctg
aaagccatgctcaacctgcacgacggacagaacaccaccatccccctgctcctggagatc
gcgcggcaaacggacagcctgaaggagcttgtcaacgccagctacacggacagctactac
aagggccagacagcactgcacatcgccatcgagagacgcaacatggccctggtgaccctc
ctggtggagaacggagcagacgtccaggctgcggcccatggggacttctttaagaaaacc
aaagggcggcctggattctacttcggtgaactgcccctgtccctggccgcgtgcaccaac
cagctgggcatcgtgaagttcctgctgcagaactcctggcagacggccgacatcagcgcc
agggactcggtgggcaacacggtgctgcacgccctggtggaggtggccgacaacacggcc
gacaacacgaagtttgtgacgagcatgtacaatgagattctgatgctgggggccaaactg
cacccgacgctgaagctggaggagctcaccaacaagaagggaatgacgccgctggctctg
gcagctgggaccgggaagatcggggtcttggcctatattctccagcgggagatccaggag
cccgagtgcaggcacctgtccaggaagttcaccgagtgggcctacgggcccgtgcactcc
tcgctgtacgacctgtcctgcatcgacacctgcgagaagaactcggtgctggaggtgatc
gcctacagcagcagcgagacccctaatcgccacgacatgctcttggtggagccgctgaac
cgactcctgcaggacaagtgggacagattcgtcaagcgcatcttctacttcaacttcctg
gtctactgcctgtacatgatcatcttcaccatggctgcctactacaggcccgtggatggc
ttgcctccctttaagatggaaaaaactggagactatttccgagttactggagagatcctg
tctgtgttaggaggagtctacttctttttccgagggattcagtatttcctgcagaggcgg
ccgtcgatgaagaccctgtttgtggacagctacagtgagatgcttttctttctgcagtca
ctgttcatgctggccaccgtggtgctgtacttcagccacctcaaggagtatgtggcttcc
atggtattctccctggccttgggctggaccaacatgctctactacacccgcggtttccag
cagatgggcatctatgccgtcatgatagagaagatgatcctgagagacctgtgccgtttc
atgtttgtctacatcgtcttcttgttcgggttttccacagcggtggtgacgctgattgaa
gacgggaagaatgactccctgccgtctgagtccacgtcgcacaggtggcgggggcctgcc
tgcaggccccccgatagctcctacaacagcctgtactccacctgcctggagctgttcaag
ttcaccatcggcatgggcgacctggagttcactgagaactatgacttcaaggctgtcttc
atcatcctgctgctggcctatgtaattctcacctacatcctcctgctcaacatgctcatc
gccctcatgggtgagactgtcaacaagatcgcacaggagagcaagaacatctggaagctg
cagagagccatcaccatcctggacacggagaagagcttccttaagtgcatgaggaaggcc
ttccgctcaggcaagctgctgcaggtggggtacacacctgatggcaaggacgactaccgg
tggtgcttcagggtggacgaggtgaactggaccacctggaacaccaacgtgggcatcatc
aacgaagacccgggcaactgtgagggcgtcaagcgcaccctgagcttctccctgcggtca
agcagagtttcaggcagacactggaagaactttgccctggtcccccttttaagagaggca
agtgctcgagataggcagtctgctcagcccgaggaagtttatctgcgacagttttcaggg
tctctgaagccagaggacgctgaggtcttcaagagtcctgccgcttccggggagaagtga
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