Homo sapiens (human): 7454
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Entry
7454 CDS
T01001
Symbol
WAS, IMD2, SCNX, THC, THC1, WASP, WASPA
Name
(RefSeq) WASP actin nucleation promoting factor
KO
K05747
Wiskott-Aldrich syndrome protein
Organism
hsa
Homo sapiens (human)
Pathway
hsa04062
Chemokine signaling pathway
hsa04520
Adherens junction
hsa04530
Tight junction
hsa04666
Fc gamma R-mediated phagocytosis
hsa05135
Yersinia infection
hsa05231
Choline metabolism in cancer
Disease
H00100
Neutropenic disorders
H00107
Other well-defined immunodeficiency syndromes
H00978
Thrombocytopenia (THC)
H01523
Wiskott-Aldrich syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
7454 (WAS)
04530 Tight junction
7454 (WAS)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
7454 (WAS)
04062 Chemokine signaling pathway
7454 (WAS)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
7454 (WAS)
09171 Infectious disease: bacterial
05135 Yersinia infection
7454 (WAS)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
7454 (WAS)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
7454 (WAS)
04990 Domain-containing proteins not elsewhere classified [BR:
hsa04990
]
7454 (WAS)
Membrane trafficking [BR:
hsa04131
]
Others
Actin-binding proteins
Nucleation-promoting factors (NPFs)
7454 (WAS)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
WASP / WAVE
7454 (WAS)
Domain-containing proteins not elsewhere classified [BR:
hsa04990
]
EVH1 / WASP homology (WH) domain-containing proteins
WH1 domain-containing proteins
7454 (WAS)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
WH1
PBD
WH2
Motif
Other DBs
NCBI-GeneID:
7454
NCBI-ProteinID:
NP_000368
OMIM:
300392
HGNC:
12731
Ensembl:
ENSG00000015285
UniProt:
P42768
Structure
PDB
PDBj
LinkDB
All DBs
Position
X:48676636..48691427
Genome browser
AA seq
502 aa
AA seq
DB search
MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGA
PSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGL
EAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPP
PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV
PAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRA
IHSSDEGEDQAGDEDEDDEWDD
NT seq
1509 nt
NT seq
+upstream
nt +downstream
nt
atgagtgggggcccaatgggaggaaggcccgggggccgaggagcaccagcggttcagcag
aacataccctccaccctcctccaggaccacgagaaccagcgactctttgagatgcttgga
cgaaaatgcttgacgctggccactgcagttgttcagctgtacctggcgctgccccctgga
gctgagcactggaccaaggagcattgtggggctgtgtgcttcgtgaaggataacccccag
aagtcctacttcatccgcctttacggccttcaggctggtcggctgctctgggaacaggag
ctgtactcacagcttgtctactccacccccacccccttcttccacaccttcgctggagat
gactgccaagcggggctgaactttgcagacgaggacgaggcccaggccttccgggccctc
gtgcaggagaagatacaaaaaaggaatcagaggcaaagtggagacagacgccagctaccc
ccaccaccaacaccagccaatgaagagagaagaggagggctcccacccctgcccctgcat
ccaggtggagaccaaggaggccctccagtgggtccgctctccctggggctggcgacagtg
gacatccagaaccctgacatcacgagttcacgataccgtgggctcccagcacctggacct
agcccagctgataagaaacgctcagggaagaagaagatcagcaaagctgatattggtgca
cccagtggattcaagcatgtcagccacgtggggtgggacccccagaatggatttgacgtg
aacaacctcgacccagatctgcggagtctgttctccagggcaggaatcagcgaggcccag
ctcaccgacgccgagacctctaaacttatctacgacttcattgaggaccagggtgggctg
gaggctgtgcggcaggagatgaggcgccaggagccacttccgccgcccccaccgccatct
cgaggagggaaccagctcccccggccccctattgtggggggtaacaagggtcgttctggt
ccactgccccctgtacctttggggattgccccacccccaccaacaccccggggaccccca
cccccaggccgagggggccctccaccaccaccccctccagctactggacgttctggacca
ctgccccctccaccccctggagctggtgggccacccatgccaccaccaccgccaccaccg
ccaccgccgcccagctccgggaatggaccagcccctcccccactccctcctgctctggtg
cctgccgggggcctggcccctggtgggggtcggggagcgcttttggatcaaatccggcag
ggaattcagctgaacaagacccctggggccccagagagctcagcgctgcagccaccacct
cagagctcagagggactggtgggggccctgatgcacgtgatgcagaagagaagcagagcc
atccactcctccgacgaaggggaggaccaggctggcgatgaagatgaagatgatgaatgg
gatgactga
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integrated database retrieval system
