| Entry |
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| Symbol |
WAS, IMD2, SCNX, THC, THC1, WASP, WASPA
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| Name |
(RefSeq) WASP actin nucleation promoting factor
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| KO |
| K05747 | Wiskott-Aldrich syndrome protein |
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| Organism |
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| Pathway |
| hsa04666 | Fc gamma R-mediated phagocytosis |
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| Disease |
| H00107 | Other well-defined immunodeficiency syndromes |
| H01523 | Wiskott-Aldrich syndrome |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
7454 (WAS)
04530 Tight junction
7454 (WAS)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
7454 (WAS)
04062 Chemokine signaling pathway
7454 (WAS)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
7454 (WAS)
09171 Infectious disease: bacterial
05135 Yersinia infection
7454 (WAS)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:hsa04131]
7454 (WAS)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:hsa04812]
7454 (WAS)
04990 Domain-containing proteins not elsewhere classified [BR:hsa04990]
7454 (WAS)
Membrane trafficking [BR:hsa04131]
Others
Actin-binding proteins
Nucleation-promoting factors (NPFs)
7454 (WAS)
Cytoskeleton proteins [BR:hsa04812]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
WASP / WAVE
7454 (WAS)
Domain-containing proteins not elsewhere classified [BR:hsa04990]
EVH1 / WASP homology (WH) domain-containing proteins
WH1 domain-containing proteins
7454 (WAS)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
X:48676636..48691427
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| AA seq |
502 aa
MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGA
PSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGL
EAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPP
PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV
PAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRA
IHSSDEGEDQAGDEDEDDEWDD |
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| NT seq |
1509 nt +upstreamnt +downstreamnt
atgagtgggggcccaatgggaggaaggcccgggggccgaggagcaccagcggttcagcag
aacataccctccaccctcctccaggaccacgagaaccagcgactctttgagatgcttgga
cgaaaatgcttgacgctggccactgcagttgttcagctgtacctggcgctgccccctgga
gctgagcactggaccaaggagcattgtggggctgtgtgcttcgtgaaggataacccccag
aagtcctacttcatccgcctttacggccttcaggctggtcggctgctctgggaacaggag
ctgtactcacagcttgtctactccacccccacccccttcttccacaccttcgctggagat
gactgccaagcggggctgaactttgcagacgaggacgaggcccaggccttccgggccctc
gtgcaggagaagatacaaaaaaggaatcagaggcaaagtggagacagacgccagctaccc
ccaccaccaacaccagccaatgaagagagaagaggagggctcccacccctgcccctgcat
ccaggtggagaccaaggaggccctccagtgggtccgctctccctggggctggcgacagtg
gacatccagaaccctgacatcacgagttcacgataccgtgggctcccagcacctggacct
agcccagctgataagaaacgctcagggaagaagaagatcagcaaagctgatattggtgca
cccagtggattcaagcatgtcagccacgtggggtgggacccccagaatggatttgacgtg
aacaacctcgacccagatctgcggagtctgttctccagggcaggaatcagcgaggcccag
ctcaccgacgccgagacctctaaacttatctacgacttcattgaggaccagggtgggctg
gaggctgtgcggcaggagatgaggcgccaggagccacttccgccgcccccaccgccatct
cgaggagggaaccagctcccccggccccctattgtggggggtaacaagggtcgttctggt
ccactgccccctgtacctttggggattgccccacccccaccaacaccccggggaccccca
cccccaggccgagggggccctccaccaccaccccctccagctactggacgttctggacca
ctgccccctccaccccctggagctggtgggccacccatgccaccaccaccgccaccaccg
ccaccgccgcccagctccgggaatggaccagcccctcccccactccctcctgctctggtg
cctgccgggggcctggcccctggtgggggtcggggagcgcttttggatcaaatccggcag
ggaattcagctgaacaagacccctggggccccagagagctcagcgctgcagccaccacct
cagagctcagagggactggtgggggccctgatgcacgtgatgcagaagagaagcagagcc
atccactcctccgacgaaggggaggaccaggctggcgatgaagatgaagatgatgaatgg
gatgactga |
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