Homo sapiens (human): 7874
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Entry
7874 CDS
T01001
Symbol
USP7, C16DELp13.2, DEL16P13.2, HAFOUS, HAUSP, TEF1
Name
(RefSeq) ubiquitin specific peptidase 7
KO
K11838
ubiquitin carboxyl-terminal hydrolase 7 [EC:
3.4.19.12
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03083
Polycomb repressive complex
hsa04068
FoxO signaling pathway
hsa05169
Epstein-Barr virus infection
hsa05203
Viral carcinogenesis
Network
nt06165
Epstein-Barr virus (EBV)
nt06523
Epigenetic regulation by Polycomb complexes
Element
N00223
EBV EBNA1 to p53-mediated transcription
N01586
Activation of PRC2.2 by ubiquitination of H2AK119
Disease
H02528
Hao-Fountain syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09126 Chromosome
03083 Polycomb repressive complex
7874 (USP7)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
7874 (USP7)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
7874 (USP7)
09172 Infectious disease: viral
05169 Epstein-Barr virus infection
7874 (USP7)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
7874 (USP7)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
7874 (USP7)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.19 Omega peptidases
3.4.19.12 ubiquitinyl hydrolase 1
7874 (USP7)
Peptidases and inhibitors [BR:
hsa01002
]
Cysteine peptidases
Family C19: ubiquitin-specific protease family
7874 (USP7)
Ubiquitin system [BR:
hsa04121
]
Deubiquitinating enzyme (DUB)
Ubiquitin-specific proteases (UBPs)
UBP/USP
7874 (USP7)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
USP7_ICP0_bdg
UCH
USP7_C2
MATH_2
MATH
UCH_1
Motif
Other DBs
NCBI-GeneID:
7874
NCBI-ProteinID:
NP_003461
OMIM:
602519
HGNC:
12630
Ensembl:
ENSG00000187555
UniProt:
Q93009
Q6U8A4
Structure
PDB
PDBj
LinkDB
All DBs
Position
16:complement(8892097..8963906)
Genome browser
AA seq
1102 aa
AA seq
DB search
MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDME
DDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQ
CNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPE
KGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRK
AVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELC
RVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNI
FESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIK
INDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKF
DDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQL
VERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNS
SLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTI
FLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVM
CDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSEL
PTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFF
KSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLN
SQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLE
CLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREV
MKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLD
HFNKAPKRSRYTYLEKAIKIHN
NT seq
3309 nt
NT seq
+upstream
nt +downstream
nt
atgaaccaccagcagcagcagcagcagcagaaagcgggcgagcagcagttgagcgagccc
gaggacatggagatggaagcgggagatacagatgacccaccaagaattactcagaaccct
gtgatcaatgggaatgtggccctgagtgatggacacaacaccgcggaggaggacatggag
gatgacaccagttggcgctccgaggcaacctttcagttcactgtggagcgcttcagcaga
ctgagtgagtcggtccttagccctccgtgttttgtgcgaaatctgccatggaagattatg
gtgatgccacgcttttatccagacagaccacaccaaaaaagcgtaggattctttctccag
tgcaatgctgaatctgattccacgtcatggtcttgccatgcacaagcagtgctgaagata
ataaattacagagatgatgaaaagtcgttcagtcgtcgtattagtcatttgttcttccat
aaagaaaatgattggggattttccaattttatggcctggagtgaagtgaccgatcctgag
aaaggatttatagatgatgacaaagttacctttgaagtctttgtacaggcggatgctccc
catggagttgcgtgggattcaaagaagcacacaggctacgtcggcttaaagaatcaggga
gcgacttgttacatgaacagcctgctacagacgttatttttcacgaatcagctacgaaag
gctgtgtacatgatgccaaccgagggggatgattcgtctaaaagcgtccctttagcatta
caaagagtgttctatgaattacagcatagtgataaacctgtaggaacaaaaaagttaaca
aagtcatttgggtgggaaactttagatagcttcatgcaacatgatgttcaggagctttgt
cgagtgttgctcgataatgtggaaaataagatgaaaggcacctgtgtagagggcaccata
cccaaattattccgcggcaaaatggtgtcctatatccagtgtaaagaagtagactatcgg
tctgatagaagagaagattattatgatatccagctaagtatcaaaggaaagaaaaatata
tttgaatcatttgtggattatgtggcagtagaacagctcgatggggacaataaatacgac
gctggggaacatggcttacaggaagcagagaaaggtgtgaaattcctaacattgccacca
gtgttacatctacaactgatgagatttatgtatgaccctcagacggaccaaaatatcaag
atcaatgataggtttgaattcccagagcagttaccacttgatgaatttttgcaaaaaaca
gatcctaaggaccctgcaaattatattcttcatgcagtcctggttcatagtggagataat
catggtggacattatgtggtttatctaaaccccaaaggggatggcaaatggtgtaaattt
gatgacgacgtggtgtcaaggtgtactaaagaggaagcaattgagcacaattatgggggt
cacgatgacgacctgtctgttcgacactgcactaatgcttacatgttagtctacatcagg
gaatcaaaactgagtgaagttttacaggcggtcaccgaccatgatattcctcagcagttg
gtggagcgattacaagaagagaaaaggatcgaggctcagaagcggaaggagcggcaggaa
gcccatctctatatgcaagtgcagatagtcgcagaggaccagttttgtggccaccaaggg
aatgacatgtacgatgaagaaaaagtgaaatacactgtgttcaaagtattgaagaactcc
tcgcttgctgagtttgttcagagcctctctcagaccatgggatttccacaagatcaaatt
cgattgtggcccatgcaagcaaggagtaatggaacaaaacgaccagcaatgttagataat
gaagccgacggcaataaaacaatgattgagctcagtgataatgaaaacccttggacaata
ttcctggaaacagttgatcccgagctggctgctagtggagcgaccttacccaagtttgat
aaagatcatgatgtaatgttatttttgaagatgtatgatcccaaaacgcggagcttgaat
tactgtgggcatatctacacaccaatatcctgtaaaatacgtgacttgctcccagttatg
tgtgacagagcaggatttattcaagatactagccttatcctctatgaggaagttaaaccg
aatttaacagagagaattcaggactatgacgtgtctcttgataaagcccttgatgaacta
atggatggtgacatcatagtatttcagaaggatgaccctgaaaatgataacagtgaatta
cccaccgcaaaggagtatttccgagatctctaccaccgcgttgatgtcattttctgtgat
aaaacaatccctaatgatcctggatttgtggttacgttatcaaatagaatgaattatttt
caggttgcaaagacagttgcacagaggctcaacacagatccaatgttgctgcagtttttc
aagtctcaaggttatagggatggcccaggtaatcctcttagacataattatgaaggtact
ttaagagatcttctacagttcttcaagcctagacaacctaagaaactttactatcagcag
cttaagatgaaaatcacagactttgagaacaggcgaagttttaaatgtatatggttaaac
agccaatttagggaagaggaaataacactatatccagacaagcatgggtgtgtccgggac
ctgttagaagaatgtaaaaaggccgtggagcttggggagaaagcatcagggaaacttagg
ctgctagaaattgtaagctacaaaatcattggtgttcatcaagaagatgaactattagaa
tgtttatctcctgcaacgagccggacgtttcgaatagaggaaatccctttggaccaggtg
gacatagacaaagagaatgagatgcttgtcacagtggcgcatttccacaaagaggtcttc
ggaacgttcggaatcccgtttttgctgaggatacaccagggcgagcattttcgagaagtg
atgaagcgaatccagagcctgctggacatccaggagaaggagtttgagaagtttaaattt
gcaattgtaatgatgggccgacaccagtacataaatgaagacgagtatgaagtaaatttg
aaagactttgagccacagcccggtaatatgtctcatcctcggccttggctagggctcgac
cacttcaacaaagccccaaagaggagtcgctacacttaccttgaaaaggccattaaaatc
cataactga
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