Homo sapiens (human): 79258
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Entry
79258 CDS
T01001
Symbol
MMEL1, MMEL2, NEP2, NEPII, NL1, NL2, SEP
Name
(RefSeq) membrane metalloendopeptidase like 1
KO
K08635
neprilysin [EC:
3.4.24.11
]
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
79258 (MMEL1)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.11 neprilysin
79258 (MMEL1)
Peptidases and inhibitors [BR:
hsa01002
]
Metallo peptidases
Family M13: neprilysin family
79258 (MMEL1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_M13_N
Peptidase_M13
ERAP1_C
Motif
Other DBs
NCBI-GeneID:
79258
NCBI-ProteinID:
NP_258428
OMIM:
618104
HGNC:
14668
Ensembl:
ENSG00000142606
UniProt:
Q495T6
B3KS82
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All DBs
Position
1:complement(2590639..2633016)
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AA seq
779 aa
AA seq
DB search
MGKSEGPVGMVESAGRAGQKRPGFLEGGLLLLLLLVTAALVALGVLYADRRGKQLPRLAS
RLCFLQEERTFVKRKPRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFAC
GGWLRRHVIPETNSRYSIFDVLRDELEVILKAVLENSTAKDRPAVEKARTLYRSCMNQSV
IEKRGSQPLLDILEVVGGWPVAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWND
DQNSSRHIIYIDQPTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCL
VQEDMVQVLELETQLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLS
SVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRV
NYRKALFGTMVEEVRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFV
ETLDELGWMDEESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENS
LQNLKVGAQRSLRKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQ
ALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSW
DLADEQNVNGFNTLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYA
QVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW
NT seq
2340 nt
NT seq
+upstream
nt +downstream
nt
atggggaagtccgaaggcccagtggggatggtggagagcgccggccgtgcagggcagaag
cgcccggggttcctggagggggggctgctgctgctgctgctgctggtgaccgctgccctg
gtggccttgggtgtcctctacgccgaccgcagagggaagcagctgccacgccttgctagc
cggctgtgcttcttacaggaggagaggacctttgtaaaacgaaaaccccgagggatccca
gaggcccaagaggtgagcgaggtctgcaccacccctggctgcgtgatagcagctgccagg
atcctccagaacatggacccgaccacggaaccgtgtgacgacttctaccagtttgcatgc
ggaggctggctgcggcgccacgtgatccctgagaccaactcaagatacagcatctttgac
gtcctccgcgacgagctggaggtcatcctcaaagcggtgctggagaattcgactgccaag
gaccggccggctgtggagaaggccaggacgctgtaccgctcctgcatgaaccagagtgtg
atagagaagcgaggctctcagcccctgctggacatcttggaggtggtgggaggctggccg
gtggcgatggacaggtggaacgagaccgtaggactcgagtgggagctggagcggcagctg
gcgctgatgaactcacagttcaacaggcgcgtcctcatcgacctcttcatctggaacgac
gaccagaactccagccggcacatcatctacatagaccagcccaccttgggcatgccctcc
cgagagtactacttcaacggcggcagcaaccggaaggtgcgggaagcctacctgcagttc
atggtgtcagtggccacgttgctgcgggaggatgcaaacctgcccagggacagctgcctg
gtgcaggaggacatggtgcaggtgctggagctggagacacagctggccaaggccacggta
ccccaggaggagagacacgacgtcatcgccttgtaccaccggatgggactggaggagctg
caaagccagtttggcctgaagggatttaactggactctgttcatacaaactgtgctatcc
tctgtcaaaatcaagctgctgccagatgaggaagtggtggtctatggcatcccctacctg
cagaaccttgaaaacatcatcgacacctactcagccaggaccatacagaactacctggtc
tggcgcctggtgctggaccgcattggtagcctaagccagagattcaaggacacacgagtg
aactaccgcaaggcgctgtttggcacaatggtggaggaggtgcgctggcgtgaatgtgtg
ggctacgtcaacagcaacatggagaacgccgtgggctccctctacgtcagggaggcgttc
cctggagacagcaagagcatggtcagagaactcattgacaaggtgcggacagtgtttgtg
gagacgctggacgagctgggctggatggacgaggagtccaagaagaaggcgcaggagaag
gccatgagcatccgggagcagatcgggcaccctgactacatcctggaggagatgaacagg
cgcctggacgaggagtactccaatctgaacttctcagaggacctgtactttgagaacagt
ctgcagaacctcaaggtgggcgcccagcggagcctcaggaagcttcgggaaaaggtggac
ccaaatctctggatcatcggggcggcggtggtcaatgcgttctactccccaaaccgaaac
cagattgtattccctgccgggatcctccagccccccttcttcagcaaggagcagccacag
gccttgaactttggaggcattgggatggtgatcgggcacgagatcacgcacggctttgac
gacaatggccggaacttcgacaagaatggcaacatgatggattggtggagtaacttctcc
acccagcacttccgggagcagtcagagtgcatgatctaccagtacggcaactactcctgg
gacctggcagacgaacagaacgtgaacggattcaacacccttggggaaaacattgctgac
aacggaggggtgcggcaagcctataaggcctacctcaagtggatggcagagggtggcaag
gaccagcagctgcccggcctggatctcacccatgagcagctcttcttcatcaactatgcc
caggtgtggtgcgggtcctaccggcccgagttcgccatccaatccatcaagacagacgtc
cacagtcccctgaagtacagggtactggggtcgctgcagaacctggccgccttcgcagac
acgttccactgtgcccggggcacccccatgcaccccaaggagcgatgccgcgtgtggtag
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