Homo sapiens (human): 80131
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Entry
80131 CDS
T01001
Symbol
LRRC8E
Name
(RefSeq) leucine rich repeat containing 8 VRAC subunit E
KO
K22038
volume-regulated anion channel
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
80131 (LRRC8E)
Ion channels [BR:
hsa04040
]
Chloride channels
Chloride channel, volume-regulated (VRAC)
80131 (LRRC8E)
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Gene cluster
GFIT
Motif
Pfam:
Pannexin_like
LRR_8
LRR_4
LRR_9
Motif
Other DBs
NCBI-GeneID:
80131
NCBI-ProteinID:
NP_001255213
OMIM:
612891
HGNC:
26272
Ensembl:
ENSG00000171017
UniProt:
Q6NSJ5
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Position
19:7888510..7902016
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AA seq
796 aa
AA seq
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MIPVAEFKQFTEQQPAFKVLKPWWDVLAEYLTVAMLMIGVFGCTLQVTQDKIICLPNHEL
QENLSEAPCQQLLPRGIPEQIGALQEVKGLKNNLDLQQYSFINQLCYETALHWYAKYFPY
LVVIHTLIFMVCTSFWFKFPGTSSKIEHFISILGKCFDSPWTTRALSEVSGENQKGPAAT
ERAAATIVAMAGTGPGKAGEGEKEKVLAEPEKVVTEPPVVTLLDKKEGEQAKALFEKVKK
FRMHVEEGDILYTMYIRQTVLKVCKFLAILVYNLVYVEKISFLVACRVETSEVTGYASFC
CNHTKAHLFSKLAFCYISFVCIYGLTCIYTLYWLFHRPLKEYSFRSVREETGMGDIPDVK
NDFAFMLHLIDQYDSLYSKRFAVFLSEVSESRLKQLNLNHEWTPEKLRQKLQRNAAGRLE
LALCMLPGLPDTVFELSEVESLRLEAICDITFPPGLSQLVHLQELSLLHSPARLPFSLQV
FLRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEGLFPQELARAATLESLRELKQLKVL
SLRSNAGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKKLAALRELELVACGLERIPHA
VFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYL
SYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEALPEELFF
CRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKAGLLVEDT
LYQGLPAEVRDKMEEE
NT seq
2391 nt
NT seq
+upstream
nt +downstream
nt
atgatcccagtggccgagttcaagcagttcacggaacagcagcctgcgttcaaggtgctc
aaaccctggtgggacgtgctggccgagtacctcaccgtggccatgctcatgattggggtc
tttggctgcaccctccaggtgacacaggacaagatcatctgtctacccaatcatgagctc
caggagaacttatcagaggccccgtgccagcaattgctgcctcgggggatccctgagcag
attggggccctgcaggaggttaaaggccttaagaacaatttggacctgcagcaatacagc
tttattaaccagctgtgttatgagacggccctgcactggtatgccaagtacttcccttac
ctcgtggtcattcacacactcatcttcatggtctgcaccagtttctggttcaagttccct
ggcaccagctccaagattgaacacttcatctccatcctgggcaagtgtttcgactctcca
tggaccaccagggccctatccgaggtctccggggagaaccagaagggcccagcagccacc
gaacgggctgcggccaccatagtggccatggcagggaccgggccggggaaggcaggggag
ggtgagaaggagaaagtgctggcggaaccggagaaggtggtgaccgagcctccagttgtc
accctgttggacaagaaggagggtgagcaagccaaagccctgtttgagaaggtgaagaag
ttccgcatgcacgtggaagagggcgacatcctgtacaccatgtacatccgacagacggtg
ctgaaagtgtgtaagttcctggccatcctggtctacaacctggtctatgtggagaagatc
agtttcctggtggcctgtagggtggagacgtcagaggtcacgggctacgccagcttctgc
tgcaaccacaccaaggcccacctcttctccaagctggccttctgttacatctcctttgtg
tgcatctacggacttacctgcatctacacgctctactggctcttccaccggcccctcaag
gagtactccttccgttccgtgcgggaggagactggcatgggggacattcctgacgtcaag
aatgacttcgccttcatgctgcacctcatcgatcagtacgactccctctactccaagcgc
ttcgccgtcttcctgtccgaggtcagcgaaagccgtctaaagcagctcaatctcaaccac
gagtggacgcccgagaagcttcgacagaagctgcagcgcaatgccgcgggccggctggag
ctggccctctgcatgctgccgggtctgcccgacaccgtctttgagctcagtgaggtggag
tcactcaggctggaggccatctgcgatatcaccttccccccggggctgtcacagctggtg
cacttgcaggagctcagcttgctccactcgcccgccaggctacccttctccttgcaggtc
ttcctgcgggaccacctgaaggtgatgcgcgtcaaatgcgaggagctccgcgaggtgccg
ctttgggtgtttgggctgcggggcttggaggagctgcacctggaggggcttttcccccag
gagctagctcgggcagccaccctggagagcctccgggagctgaagcagctcaaggtgttg
tccctccggagcaacgccgggaaggtgccagccagtgtgaccgacgttgctggccacctg
cagaggctcagcctgcacaacgatggggcccgtctggttgccctgaacagcctcaagaag
ctggcggcattgcgggagctggagctggtggcctgcgggctggagcgcatcccccatgca
gtgttcagcctgggtgcgctgcaggaacttgacctcaaggacaaccacctgcgctccatc
gaggaaatcctcagcttccagcactgccggaagctggtcacgctcaggctgtggcacaac
cagatcgcctacgtccctgagcacgtgcggaagctcaggagcctggagcagctctacctc
agctacaacaagctggagaccctgccctcccagctcggcctgtgctcaggcctccgtctg
ctggatgtgtcccacaatgggctacactccctgccacccgaggtgggcctcctgcagaac
ctacagcacctggccctctcctacaatgccctggaggccctgcccgaagagctcttcttc
tgccgcaagctgcggacgttgcttctgggcgacaaccagctgagccagctctcgccccac
gtgggtgccctcagagccctcagccgcctggagctcaaaggcaaccgcttagaggcgctg
ccagaagaacttggcaactgtggggggctcaagaaggcggggctcctggtggaagacacg
ctttaccagggtctgccggcagaagtgcgggacaagatggaggaggaatga
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