Homo sapiens (human): 80271
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Entry
80271 CDS
T01001
Symbol
ITPKC, IP3-3KC, IP3KC
Name
(RefSeq) inositol-trisphosphate 3-kinase C
KO
K00911
1D-myo-inositol-triphosphate 3-kinase [EC:
2.7.1.127
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00562
Inositol phosphate metabolism
hsa01100
Metabolic pathways
hsa04020
Calcium signaling pathway
hsa04070
Phosphatidylinositol signaling system
Module
hsa_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
80271 (ITPKC)
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
80271 (ITPKC)
04070 Phosphatidylinositol signaling system
80271 (ITPKC)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.127 inositol-trisphosphate 3-kinase
80271 (ITPKC)
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Gene cluster
GFIT
Motif
Pfam:
IPK
Motif
Other DBs
NCBI-GeneID:
80271
NCBI-ProteinID:
NP_079470
OMIM:
606476
HGNC:
14897
Ensembl:
ENSG00000086544
UniProt:
Q96DU7
Structure
PDB
PDBj
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Position
19:40717112..40740860
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AA seq
683 aa
AA seq
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MRRCPCRGSLNEAEAGALPAAARMGLEAPRGGRRRQPGQQRPGPGAGAPAGRPEGGGPWA
RTEGSSLHSEPERAGLGPAPGTESPQAEFWTDGQTEPAAAGLGVETERPKQKTEPDRSSL
RTHLEWSWSELETTCLWTETGTDGLWTDPHRSDLQFQPEEASPWTQPGVHGPWTELETHG
SQTQPERVKSWADNLWTHQNSSSLQTHPEGACPSKEPSADGSWKELYTDGSRTQQDIEGP
WTEPYTDGSQKKQDTEAARKQPGTGGFQIQQDTDGSWTQPSTDGSQTAPGTDCLLGEPED
GPLEEPEPGELLTHLYSHLKCSPLCPVPRLIITPETPEPEAQPVGPPSRVEGGSGGFSSA
SSFDESEDDVVAGGGGASDPEDRSGSKPWKKLKTVLKYSPFVVSFRKHYPWVQLSGHAGN
FQAGEDGRILKRFCQCEQRSLEQLMKDPLRPFVPAYYGMVLQDGQTFNQMEDLLADFEGP
SIMDCKMGSRTYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQW
RETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYVACLE
ELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLPWAEG
NREDGYLWGLDNMICLLQGLAQS
NT seq
2052 nt
NT seq
+upstream
nt +downstream
nt
atgaggcgctgcccgtgccgtgggagcctgaacgaggcggaggccggggcgctgcccgcg
gcggcccgcatgggactggaggcgccgcgaggagggcggcggcggcagccgggacagcag
cgacctgggcccggcgcaggggccccggcggggcggccggaggggggcgggccctgggcc
cggacagaggggtccagcctccacagcgagcctgagagggccggcctcgggcctgcgccg
gggacagagagtccgcaggcagaattctggacagacggacagactgagcccgcggcagct
ggccttggagtagagaccgagaggcccaagcaaaagacggagccagacaggtccagcctc
cggacgcatctagaatggagctggtcagagctggagacgacttgtctttggacggagacc
gggacagatggcctttggactgatccgcacaggtccgacctccagtttcagcccgaggag
gccagcccctggacacagccaggggttcatgggccctggacagagctggaaacgcatggg
tcacagactcagccagagagggtcaagtcctgggctgataacctctggacccaccagaac
agttccagcctccagactcacccagaaggagcctgtccctcaaaagagccaagtgctgat
ggctcctggaaagaattgtatactgatggctccaggacacaacaggatattgaaggtccc
tggacagagccatatactgatggctcccagaaaaaacaggatactgaagcagccaggaaa
cagcctggcactggtggtttccaaatacaacaggatactgatggctcctggacacaacct
agcactgacggttcccagacagcacctgggacagactgcctcttgggagagcctgaggat
ggcccattagaggaaccagagcctggagaattgctgactcacctgtactctcacctgaag
tgtagccccctgtgccctgtgccccgcctcatcattacccctgagacccctgagcctgag
gcccagccagtgggacccccctcccgggttgaggggggcagcggcggcttctcctctgcc
tcttctttcgacgagtctgaggatgacgtggtggccgggggcggaggtgccagcgatccc
gaggacaggtctgggagcaaaccctggaagaagctgaagacagttctgaagtattcaccc
tttgtggtctccttccgaaaacactacccttgggtccagctttctggacatgctgggaac
ttccaggcaggagaggatggtcggattctgaaacgtttctgtcagtgtgagcagcgcagc
ctggagcagctgatgaaagacccgctgcgacctttcgtgcctgcctactatggcatggtg
ctgcaggatggccagaccttcaaccagatggaagacctcctggctgactttgagggcccc
tccattatggactgcaagatgggcagcaggacctatctggaagaggagctagtgaaggca
cgggaacgtccccgtccccggaaggacatgtatgagaagatggtggctgtggaccctggg
gcccctacccctgaggagcatgcccagggtgcagtcaccaagccccgctacatgcagtgg
agggaaaccatgagctccacctctaccctgggcttccggatcgagggcatcaagaaggca
gatgggacctgtaacaccaacttcaagaagacgcaggcactggagcaggtgacaaaagtg
ctggaggacttcgtggatggagaccacgtcatcctgcaaaagtacgtggcatgcctagaa
gaacttcgtgaagctctggagatctcccccttcttcaagacccacgaggtggtaggcagc
tccctcctcttcgtgcacgaccacaccggcctggccaaggtctggatgatagacttcggc
aagacggtggccttgcccgaccaccagacgctcagccacaggctgccctgggctgagggc
aaccgtgaggacggctacctctggggcctggacaacatgatctgcctcctgcaggggctg
gcacagagctga
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