Homo sapiens (human): 81792
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Entry
81792 CDS
T01001
Symbol
ADAMTS12, PRO4389
Name
(RefSeq) ADAM metallopeptidase with thrombospondin type 1 motif 12
KO
K08626
a disintegrin and metalloproteinase with thrombospondin motifs 12 [EC:3.4.24.-]
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
81792 (ADAMTS12)
Peptidases and inhibitors [BR:
hsa01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
81792 (ADAMTS12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TSP1_ADAMTS
TSP_1
ADAMTS_spacer1
Reprolysin
ADAMTS_CR_2
Pep_M12B_propep
TSP1_CCN
Reprolysin_5
TSP1_spondin
ADAMTS_CR_3
Reprolysin_3
Reprolysin_2
Reprolysin_4
Peptidase_M10
Motif
Other DBs
NCBI-GeneID:
81792
NCBI-ProteinID:
NP_112217
OMIM:
606184
HGNC:
14605
Ensembl:
ENSG00000151388
UniProt:
P58397
LinkDB
All DBs
Position
5:complement(33523535..33891990)
Genome browser
AA seq
1594 aa
AA seq
DB search
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRV
DASGHFLSYGLHYPITSSRRKRDLDGSEDWVYYRISHEEKDLFFNLTVNQGFLSNSYIME
KRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTGFFQLPHGDFFIEPVK
KHPLVEGGYHPHIVYRRQKVPETKEPTCGLKDSVNISQKQELWREKWERHNLPSRSLSRR
SISKERWVETLVVADTKMIEYHGSENVESYILTIMNMVTGLFHNPSIGNAIHIVVVRLIL
LEEEEQGLKIVHHAEKTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGFNRPCET
LGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGRHPYIMS
RQLQYDPTPLTWSKCSEEYITRFLDRGWGFCLDDIPKKKGLKSKVIAPGVIYDVHHQCQL
QYGPNATFCQEVENVCQTLWCSVKGFCRSKLDAAADGTQCGEKKWCMAGKCITVGKKPES
IPGGWGRWSPWSHCSRTCGAGVQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPCRSEA
PTFRQMQCSEFDTVPYKNELYHWFPIFNPAHPCELYCRPIDGQFSEKMLDAVIDGTPCFE
GGNSRNVCINGICKMVGCDYEIDSNATEDRCGVCLGDGSSCQTVRKMFKQKEGSGYVDIG
LIPKGARDIRVMEIEGAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKLAGTVFQYDRKGDL
EKLMATGPTNESVWIQLLFQVTNPGIKYEYTIQKDGLDNDVEQQMYFWQYGHWTECSVTC
GTGIRRQTAHCIKKGRGMVKATFCDPETQPNGRQKKCHEKACPPRWWAGEWEACSATCGP
HGEKKRTVLCIQTMVSDEQALPPTDCQHLLKPKTLLSCNRDILCPSDWTVGNWSECSVSC
GGGVRIRSVTCAKNHDEPCDVTRKPNSRALCGLQQCPSSRRVLKPNKGTISNGKNPPTLK
PVPPPTSRPRMLTTPTGPESMSTSTPAISSPSPTTASKEGDLGGKQWQDSSTQPELSSRY
LISTGSTSQPILTSQSLSIQPSEENVSSSDTGPTSEGGLVATTTSGSGLSSSRNPITWPV
TPFYNTLTKGPEMEIHSGSGEEREQPEDKDESNPVIWTKIRVPGNDAPVESTEMPLAPPL
TPDLSRESWWPPFSTVMEGLLPSQRPTTSETGTPRVEGMVTEKPANTLLPLGGDHQPEPS
GKTANRNHLKLPNNMNQTKSSEPVLTEEDATSLITEGFLLNASNYKQLTNGHGSAHWIVG
NWSECSTTCGLGAYWRRVECSTQMDSDCAAIQRPDPAKRCHLRPCAGWKVGNWSKCSRNC
SGGFKIREIQCVDSRDHRNLRPFHCQFLAGIPPPLSMSCNPEPCEAWQVEPWSQCSRSCG
GGVQERGVFCPGGLCDWTKRPTSTMSCNEHLCCHWATGNWDLCSTSCGGGFQKRTVQCVP
SEGNKTEDQDQCLCDHKPRPPEFKKCNQQACKKSADLLCTKDKLSASFCQTLKAMKKCSV
PTVRAECCFSCPQTHITHTQRQRRQRLLQKSKEL
NT seq
4785 nt
NT seq
+upstream
nt +downstream
nt
atgccatgtgcccagaggagctggcttgcaaacctttccgtggtggctcagctccttaac
tttggggcgctttgctatgggagacagcctcagccaggcccggttcgcttcccggacagg
aggcaagagcattttatcaagggcctgccagaataccacgtggtgggtccagtccgagta
gatgccagtgggcattttttgtcatatggcttgcactatcccatcacgagcagcaggagg
aagagagatttggatggctcagaggactgggtgtactacagaatttctcacgaggagaag
gacctgttttttaacttgacggtcaatcaaggatttctttccaatagctacatcatggag
aagagatatgggaacctctcccatgttaagatgatggcttcctctgcccccctctgccat
ctcagtggcacggttctacagcagggcaccagagttgggacggcagccctcagtgcctgc
catggactgactggatttttccaactaccacatggagactttttcattgaacccgtgaag
aagcatccactggttgagggagggtaccacccgcacatcgtttacaggaggcagaaagtt
ccagaaaccaaggagccaacctgtggattaaaggacagtgttaacatctcccagaagcaa
gagctatggcgggagaagtgggagaggcacaacttgccaagcagaagcctctctcggcgt
tccatcagcaaggagagatgggtggagacactggtggtggccgacacaaagatgattgaa
taccatgggagtgagaatgtggagtcctacatcctcaccatcatgaacatggtcactggg
ttgttccataacccaagcattggcaatgcaattcacattgttgtggttcggctcattcta
ctcgaagaagaagagcaaggactgaaaatagttcaccatgcagaaaagacactgtctagc
ttctgcaagtggcagaagagtatcaatcccaagagtgacctcaatcctgttcatcacgac
gtggctgtccttctcaccagaaaggacatctgtgctggtttcaatcgcccctgcgagacc
ctgggcctgtctcacctttcaggaatgtgtcagcctcaccgcagttgtaacatcaatgaa
gattcgggactccctctggctttcacaattgcccatgagctaggacacagcttcggcatc
cagcatgatgggaaagaaaatgactgtgagcctgtgggcagacatccgtacatcatgtcc
cgccagctccagtacgatcccactccgctgacatggtccaagtgcagcgaggagtacatc
acccgcttcttggaccgaggctgggggttctgtcttgatgacatacctaaaaagaaaggc
ttgaagtccaaggtcattgcccccggagtgatctatgatgttcaccaccagtgccagcta
caatatggacccaatgctaccttctgccaggaagtagaaaacgtctgccagacactgtgg
tgctccgtgaagggcttttgtcgctctaagctggacgctgctgcagatggaactcaatgt
ggtgagaagaagtggtgtatggcaggcaagtgcatcacagtggggaagaaaccagagagc
attcctggaggctggggccgctggtcaccctggtcccactgttccaggacctgtggggct
ggagtccagagcgcagagaggctctgcaacaaccccgagccaaagtttggagggaaatat
tgcactggagaaagaaaacgctatcgcttgtgcaacgtccacccctgtcgctcagaggca
ccaacatttcggcagatgcagtgcagtgaatttgacactgttccctacaagaatgaactc
taccactggtttcccatttttaacccagcacatccttgtgagctctactgccgacccata
gatggccagttttctgagaaaatgctggatgctgtcattgatggtaccccttgctttgaa
ggcggcaacagcagaaatgtctgtattaatggcatatgtaagatggttggctgtgactat
gagatcgattccaatgccaccgaggatcgctgcggtgtgtgcctgggagatggctcttcc
tgccagactgtgagaaagatgtttaagcagaaggaaggatctggttatgttgacattggg
ctcattccaaaaggagcaagggacataagagtgatggaaattgagggagctggaaacttc
ctggccatcaggagtgaagatcctgaaaaatattacctgaatggagggtttattatccag
tggaacgggaactataagctggcagggactgtctttcagtatgacaggaaaggagacctg
gaaaagctgatggccacaggtcccaccaatgagtctgtgtggatccagcttctattccag
gtgactaaccctggcatcaagtatgagtacacaatccagaaagatggccttgacaatgat
gttgagcagcagatgtacttctggcagtacggccactggacagagtgcagtgtgacctgc
gggacaggtatccgccgccaaactgcccattgcataaagaagggccgcgggatggtgaaa
gctacattctgtgacccagaaacacagcccaatgggagacagaagaagtgccatgaaaag
gcttgtccacccaggtggtgggcaggggagtgggaagcatgctcggcgacatgcgggccc
cacggggagaagaagcgaaccgtgctgtgcatccagaccatggtctctgacgagcaggct
ctcccgcccacagactgccagcacctgctgaagcccaagaccctcctttcctgcaacaga
gacatcctgtgcccctcggactggacagtgggcaactggagtgagtgttctgtttcctgt
ggtggtggagtgcggattcgcagtgtcacatgtgccaagaaccatgatgaaccttgcgat
gtgacaaggaaacccaacagccgagctctgtgtggcctccagcaatgcccttctagccgg
agagttctgaaaccaaacaaaggcactatttccaatggaaaaaacccaccaacactaaag
cccgtccctccacctacatccaggcccagaatgctgaccacacccacagggcctgagtct
atgagcacaagcactccagcaatcagcagccctagtcctaccacagcctccaaagaagga
gacctgggtgggaaacagtggcaagatagctcaacccaacctgagctgagctctcgctat
ctcatttccactggaagcacttcccagcccatcctcacttcccaatccttgagcattcag
ccaagtgaggaaaatgtttccagttcagatactggtcctacctcggagggaggccttgta
gctacaacaacaagtggttctggcttgtcatcttcccgcaaccctatcacttggcctgtg
actccattttacaataccttgaccaaaggtccagaaatggagattcacagtggctcaggg
gaagaaagagaacagcctgaggacaaagatgaaagcaatcctgtaatatggaccaagatc
agagtacctggaaatgacgctccagtggaaagtacagaaatgccacttgcacctccacta
acaccagatctcagcagggagtcctggtggccacccttcagcacagtaatggaaggactg
ctccccagccaaaggcccactacttccgaaactgggacacccagagttgaggggatggtt
actgaaaagccagccaacactctgctccctctgggaggagaccaccagccagaaccctca
ggaaagacggcaaaccgtaaccacctgaaacttccaaacaacatgaaccaaacaaaaagt
tctgaaccagtcctgactgaggaggatgcaacaagtctgattactgagggctttttgcta
aatgcctccaattacaagcagctcacaaacggccacggctctgcacactggatcgtcgga
aactggagcgagtgctccaccacatgtggcctgggggcctactggagaagggtggagtgc
agcacccagatggattctgactgtgcggccatccagagacctgaccctgcaaaaagatgc
cacctccgtccctgtgctggctggaaagtgggaaactggagcaagtgctccagaaactgc
agtgggggcttcaagatacgcgagattcagtgcgtggacagccgggaccaccggaacctg
aggccatttcactgccagttcctggccggcattcctcccccattgagcatgagctgtaac
ccggagccctgtgaggcgtggcaggtggagccttggagccagtgctccaggtcctgtgga
ggtggagttcaggagagaggagtgttctgtccaggaggcctctgtgattggacaaaaaga
cccacatccaccatgtcttgcaatgagcacctgtgctgtcactgggccactgggaactgg
gacctgtgttccacttcctgtggaggtggctttcagaagaggactgtccaatgtgtgccc
tcagagggcaataaaactgaagaccaagaccaatgtctatgtgatcacaaacccagacct
ccagaattcaaaaaatgcaaccagcaggcctgcaagaaaagtgccgatttactttgcact
aaggacaaactgtcagccagtttctgccagacactgaaagccatgaagaaatgttctgtg
cccaccgtgagggctgagtgctgcttctcgtgtccccagacacacatcacacacacccaa
aggcaaagaaggcaacggttgctccaaaagtcaaaagaactctaa
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